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Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced receptor activation at 100 uM relative to UDP
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at rat P2Y6 receptor assessed as IP accumulation by SPA
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at rat P2Y6 receptor
Assay data:1 Tested
Agonist activity at P2Y6 receptor in Wistar rat microglia assessed as increase in intracellular calcium concentration by ratiometric fura-2 fluorescence method
Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM after 300 secs by ratiometric fura-2 fluorescence method in presence of U73122
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM after 600 secs by ratiometric fura-2 fluorescence method in presence of thapsigargin
Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM after 600 secs by ratiometric fura-2 fluorescence method in presence of xestospongin C
Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM by ratiometric fura-2 fluorescence method in presence of reactive blue 2
Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM in presence of suramin by ratiometric fura-2 fluorescence method
Activity at P2Y6 receptor in Wistar rat microglia assessed as inhibition of intracellular calcium concentration at 100 uM by ratiometric fura-2 fluorescence method in presence of MRS2578
Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia assessed as formation of lamellipodia-like membrane ruffles at 100 uM after 5 mins
Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia assessed as formation of lamellipodia-like membrane ruffles at 10 uM after 5 mins
Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia at 100 uM by chemotaxis assay
Assay data:1 Active, 2 Tested
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization at 100 uM by NOVOstar plate reader
Assay data:13 Tested
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization by NOVOstar plate reader
Purinergic P2Y Eurofins Panlabs panel
SummaryRelated BioAssays by Target
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation spectrofluorimetric analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by dual-excitation spectrofluorimetric analysis
Assay data:3 Active, 3 Tested
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellular calcium concentration by dual-excitation spectrofluorimetric analysis
Assay data:3 Tested
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay
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