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Activity at mouse recombinant adenosine A2B receptor expressed in CHO cells assessed per mg of protein
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition against A2B-Adenosine Receptor in mouse NIH 3T3 fibroblast cell membranes
Assay data:2 Tested
Inhibition against A2B-Adenosine Receptor in mouse NIH 3T3 fibroblast cell membranes (functional antagonist activity)
Assay data:4 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Assay data:1 Active, 1 Tested
Activity at mouse A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced intracellular cAMP levels by ELISA
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Activity at mouse A3 receptor expressed in CHO cells assessed as inhibition of NECA-induced intracellular cAMP levels at 10 uM by ELISA
Inhibition of NECA-induced IL6 production in Swiss mouse fibroblasts after 24 hrs by ELISA
Antagonist activity at mouse adenosine A2B receptor expressed in NIH3T3 cells assessed as inhibition of NECA-induced cAMP accumulation
Activation of mouse adenosine A2B receptor
Binding affinity to mouse adenosine A2B receptor
Displacement of [3H]PSB-603 from mouse recombinant adenosine A2B receptor expressed in CHO cells
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Displacement of [3H] DPCPX from mouse adenosine A2B receptor expressed in HEK293 cells at 10 uM incubated for 60 mins by radioligand binding assay
Antagonist activity at mouse adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced increase of intracellular cAMP level after 30 mins by ELISA
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
Mouse A2B receptor (Adenosine receptors)
Assay data:15 Active, 15 Tested
Displacement of [3H]PSB-603 from recombinant mouse adenosine A2B receptor expressed in CHO cell membranes after 75 mins by liquid scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Displacement of [3H]PSB-603 from recombinant mouse A2B adenosine receptor expressed in CHO cell membranes measured after 75 mins in presence of adenosine deaminase by liquid scintillation counting method
Assay data:4 Active, 3 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 4 Tested
Displacement of [3H]PSB-603 from recombinant mouse A2B adenosine receptor expressed in CHO cell membranes measured after 75 mins by liquid scintillation counting method
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
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