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Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells at 300 uM by FMP assay
Assay data:7 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of acetylcholine-induced effect after 30 min by FLIPR potential blue assay
Assay data:1 Active, 1 Tested
Agonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells at 300 uM after 30 min by FLIPR potential blue assay
Agonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells at >=100 uM after 30 min by FLIPR potential blue assay
Assay data:5 Active, 5 Tested
Agonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells at >=30 uM after 30 min by FLIPR potential blue assay
Assay data:2 Active, 2 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Inhibition of [3H]nicotine binding to alpha4 nicotinic acetylcholine receptor in Mus musculus (mouse) M10 cells co-expressing beta2 nicotinic acetylcholine receptor subunits
Assay data:8 Active, 1 Activity ≤ 1 nM, 7 Activity ≤ 1 µM, 8 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Activity at alpha6alpha4beta3beta2 nAChR in mouse striatal synaptosomes assessed as alpha-conotoxic MII-resistant DA release relative to control
Assay data:12 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activity at alpha6alpha4beta3beta2 nAChR in mouse striatal synaptosomes assessed as alpha-conotoxic MII-resistant DA release
Assay data:8 Active, 7 Activity ≤ 1 µM, 10 Tested
Binding affinity against Nicotinic acetylcholine receptor using [3H](-)-nicotine radioligand
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.
Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested
Compound was tested for the binding affinity towards nicotinic acetylcholine receptor
Assay data:2 Tested
Compound was tested for the binding affinity towards Nicotinic acetylcholine receptor
Assay data:4 Tested
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