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Induction of katanin p60 subunit-mediated JNK signaling pathway activation in human NCI-H1975 cells assessed as increase in c-Jun phosphorylation at S63 residues at 300 nM after 9 hrs by phospho-kinase antibody array method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
Summary
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Induction of katanin p60 subunit-mediated JNK signaling pathway activation in human NCI-H1975 cells assessed as increase in JNK phosphorylation at T183/Y185 and T221/Y223 residues at 300 nM after 9 hrs by phospho-kinase antibody array method
Binding affinity to katanin p60 in human NCI-H1975 cells using biotin labelled compound incubated for 16 hrs by streptavidin based immunoprecipitation method
Assay data:2 Active, 3 Tested
Induction of katanin p60 subunit-mediated JNK signaling pathway activation assessed as increase in phosphorylation level at T183/Y185 residues in human NCI-H1975 cells at 300 nM after 6 to 12 hrs by immunoblot analysis
Induction of katanin p60 subunit-mediated JNK signaling pathway activation assessed as increase in c-Jun phosphorylation level at S63 residues in human NCI-H1975 cells at 300 nM after 6 to 12 hrs by immunoblot analysis
Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells at 300 nM after 12 hrs by DAPI staining based confocal laser microscopy
Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in soluble form at 300 nM after 1 hr by immunoblot analysis (Rvb = 37%)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in polymer form at 300 nM after 1 hr by immunoblot analysis (Rvb = 63%)
Induction of katanin p60 subunit-mediated microtubule fragmentation in human NCI-H1975 cells assessed as alpha-tubulin level in soluble form at 600 nM after 1 hr by immunoblot analysis (Rvb = 37%)
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