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Agonist activity mouse FFA1 by by BRET based beta-arrestin-2 interaction assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at mouse GPR120
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at mouse GPR120 relative to control
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Agonist activity at mouse FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR
Agonist activity at mouse FFA4 receptor expressed in U2OS cells assessed as maximal calcium mobilization after 24 hrs by FLIPR relative to control
Inhibition of mouse FFA4 receptor expressed in U2OS cells
Agonist activity at mouse FFA4 receptor in mouse MIN6 cells assessed as induction of glucose-induced insulin secretion
Agonist activity at mouse FFA4 receptor in mouse MIN6 cells assessed as induction of glucose-induced insulin secretion at 50 uM in presence of 4-methyl-N-(9H-xanthen-9-yl)benzenesulfonamide
Agonist activity at mouse FFA4 receptor in mouse MIN6 cells assessed as induction of glucose-induced insulin secretion by AlphaLISA
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
Agonist activity mouse FFA4 by Gq-dependent calcium mobilization assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Agonist activity mouse FFA1 up to 100 uM by Gq-dependent calcium mobilization assay
Assay data:3 Tested
Agonist activity mouse FFA4 by by BRET based beta-arrestin-2 interaction assay
Invivo agonist activity at GPR120 in C57BL/6 mouse assessed as reduction in glucose AUC levels at 30 mg/kg,po and measured upto 120 mins by OGTT test
Agonist activity at mouse GPR120 expressed in CHOK1 cells measured after 60 mins by IP1-HTRF assay
Assay data:35 Active, 33 Activity ≤ 1 µM, 37 Tested
Agonist activity at mouse GPR120 expressed in CHOK1 cells measured after 60 mins by IP1-HTRF assay relative to basal level
Assay data:35 Tested
Agonist activity at mouse GPR120 expressed in CHOK1 cells assessed as increase in IP1 accumulation after 60 mins by HTRF assay
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Agonist activity at mouse GPR120 expressed in human U2OS cells assessed as beta-arrestin recruitment after 90 mins by luminescence assay
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
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