LOCUS NM_021732 1422 bp mRNA linear PRI 24-JUN-2018
DEFINITION Homo sapiens arginine vasopressin induced 1 (AVPI1), mRNA.
ACCESSION NM_021732
VERSION NM_021732.2
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1422)
AUTHORS Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N,
Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani
K, Hao T, Cusick ME, Hill DE, Roth FP, Braun P and Vidal M.
TITLE Next-generation sequencing to generate interactome datasets
JOURNAL Nat. Methods 8 (6), 478-480 (2011)
PUBMED 21516116
REFERENCE 2 (bases 1 to 1422)
AUTHORS Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe
JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A,
Wavrant-De Vrieze F, Kaleem M, Hollingworth P, Jehu L, Foy C,
Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J,
White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L,
Morris JC, Thal L, Owen M, Williams J and Goate A.
TITLE A scan of chromosome 10 identifies a novel locus showing strong
association with late-onset Alzheimer disease
JOURNAL Am. J. Hum. Genet. 78 (1), 78-88 (2006)
PUBMED 16385451
REMARK GeneRIF: Observational study of gene-disease association. (HuGE
Navigator)
REFERENCE 3 (bases 1 to 1422)
AUTHORS Wan D, Gong Y, Qin W, Zhang P, Li J, Wei L, Zhou X, Li H, Qiu X,
Zhong F, He L, Yu J, Yao G, Jiang H, Qian L, Yu Y, Shu H, Chen X,
Xu H, Guo M, Pan Z, Chen Y, Ge C, Yang S and Gu J.
TITLE Large-scale cDNA transfection screening for genes related to cancer
development and progression
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (44), 15724-15729 (2004)
PUBMED 15498874
REMARK Erratum:[Proc Natl Acad Sci U S A. 2004 Dec 14:101(50):17565]
REFERENCE 4 (bases 1 to 1422)
AUTHORS Thomas CP, Loftus RW and Liu KZ.
TITLE AVP-induced VIT32 gene expression in collecting duct cells occurs
via trans-activation of a CRE in the 5'-flanking region of the
VIT32 gene
JOURNAL Am. J. Physiol. Renal Physiol. 287 (3), F460-F468 (2004)
PUBMED 15140762
REFERENCE 5 (bases 1 to 1422)
AUTHORS Deloukas P, Earthrowl ME, Grafham DV, Rubenfield M, French L,
Steward CA, Sims SK, Jones MC, Searle S, Scott C, Howe K, Hunt SE,
Andrews TD, Gilbert JG, Swarbreck D, Ashurst JL, Taylor A, Battles
J, Bird CP, Ainscough R, Almeida JP, Ashwell RI, Ambrose KD,
Babbage AK, Bagguley CL, Bailey J, Banerjee R, Bates K, Beasley H,
Bray-Allen S, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J,
Cahill P, Camire D, Carter NP, Chapman JC, Clark SY, Clarke G, Clee
CM, Clegg S, Corby N, Coulson A, Dhami P, Dutta I, Dunn M, Faulkner
L, Frankish A, Frankland JA, Garner P, Garnett J, Gribble S,
Griffiths C, Grocock R, Gustafson E, Hammond S, Harley JL, Hart E,
Heath PD, Ho TP, Hopkins B, Horne J, Howden PJ, Huckle E, Hynds C,
Johnson C, Johnson D, Kana A, Kay M, Kimberley AM, Kershaw JK,
Kokkinaki M, Laird GK, Lawlor S, Lee HM, Leongamornlert DA, Laird
G, Lloyd C, Lloyd DM, Loveland J, Lovell J, McLaren S, McLay KE,
McMurray A, Mashreghi-Mohammadi M, Matthews L, Milne S, Nickerson
T, Nguyen M, Overton-Larty E, Palmer SA, Pearce AV, Peck AI, Pelan
S, Phillimore B, Porter K, Rice CM, Rogosin A, Ross MT, Sarafidou
T, Sehra HK, Shownkeen R, Skuce CD, Smith M, Standring L, Sycamore
N, Tester J, Thorpe A, Torcasso W, Tracey A, Tromans A, Tsolas J,
Wall M, Walsh J, Wang H, Weinstock K, West AP, Willey DL, Whitehead
SL, Wilming L, Wray PW, Young L, Chen Y, Lovering RC, Moschonas NK,
Siebert R, Fechtel K, Bentley D, Durbin R, Hubbard T,
Doucette-Stamm L, Beck S, Smith DR and Rogers J.
TITLE The DNA sequence and comparative analysis of human chromosome 10
JOURNAL Nature 429 (6990), 375-381 (2004)
PUBMED 15164054
REFERENCE 6 (bases 1 to 1422)
AUTHORS Nicod M, Michlig S, Flahaut M, Salinas M, Fowler Jaeger N,
Horisberger JD, Rossier BC and Firsov D.
TITLE A novel vasopressin-induced transcript promotes MAP kinase
activation and ENaC downregulation
JOURNAL EMBO J. 21 (19), 5109-5117 (2002)
PUBMED 12356727
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AF131791.1.
[WARNING] On Nov 23, 2018 this sequence was replaced by
NM_021732.3.
On Jun 12, 2008 this sequence version replaced NM_021732.1.
##Evidence-Data-START##
Transcript exon combination :: AF131791.1, SRR1660805.300589.1
[ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMN03267753 [ECO:0000348]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-1422 AF131791.1 1-1422
FEATURES Location/Qualifiers
source 1..1422
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="10"
/map="10q24.2"
gene 1..1422
/gene="AVPI1"
/gene_synonym="PP5395; VIP32; VIT32"
/note="arginine vasopressin induced 1"
/db_xref="GeneID:60370"
/db_xref="HGNC:HGNC:30898"
exon 1..505
/gene="AVPI1"
/gene_synonym="PP5395; VIP32; VIT32"
/inference="alignment:Splign:2.1.0"
misc_feature 504..506
/gene="AVPI1"
/gene_synonym="PP5395; VIP32; VIT32"
/note="upstream in-frame stop codon"
exon 506..802
/gene="AVPI1"
/gene_synonym="PP5395; VIP32; VIT32"
/inference="alignment:Splign:2.1.0"
CDS 516..959
/gene="AVPI1"
/gene_synonym="PP5395; VIP32; VIT32"
/note="vasopressin-induced transcript; AVP-induced protein
1"
/codon_start=1
/product="arginine vasopressin-induced protein 1"
/protein_id="NP_068378.2"
/db_xref="CCDS:CCDS7470.1"
/db_xref="GeneID:60370"
/db_xref="HGNC:HGNC:30898"
/translation="MGTPASVVSEPPPWQAPIEARGRKQASANIFQDAELLQIQALFQ
RSGDQLAEERAQIIWECAGDHRVAEALKRLRRKRPPRQKPLGHSLHHCSRLRILEPHS
ALANPQSATETASSEQYLHSRKKSARIRRNWRKSGPTSYLHQIRH"
exon 803..1404
/gene="AVPI1"
/gene_synonym="PP5395; VIP32; VIT32"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 ggctcgcctg ggagctcata cctggctagg gccgaggatt ggctgttccg gggctaggga
61 gcgctttctc ccgggaaccg cggctgtgac ccaagtggcc cggaccagtt tggggctgcg
121 tgcggcctgc ctcaagcaac caggtacgta ggtcggcggc ccagctcggc gctgcggtgg
181 gagccggagg gcgacagtca gagccggggt gccagcggga cgcgaccgcc agatccactt
241 aggaccccgt cgttctgcga agcggccacg tctgagtccc ggggcctcct cgtgctgcag
301 atgtcgcctt aggacctcgg ccaggatacc ctctgccatg ctcttgtgct gcccgtgatc
361 accgactggc ccttgtaagc accttcgcag caggaagccc agagctgcgc ctgccctttc
421 tgaaggctgt ggaagaggtt ggagtgggcg catcttagct tgccccatcc ccatttgagg
481 tctgtcggag ctgcccttca gtgtgagcat ccacaatggg taccccagcc tcggtggtca
541 gtgagccacc cccttggcag gccccgattg aggcccgggg ccgcaagcag gcctcggcca
601 acatcttcca ggacgccgag ctgctgcaga tccaagccct gtttcaacgc agcggggacc
661 agctggccga ggaacgggca cagatcatct gggaatgtgc aggggaccac cgtgtggctg
721 aggccctcaa gaggctgcgc aggaagaggc ccccaaggca gaaacccctg ggccactcgc
781 tacaccactg cagccgcctc agaatcctgg agccccactc tgcactggcc aacccacaga
841 gtgccacaga gacagcctcc agtgagcagt atctgcactc taggaagaaa agtgccagga
901 tccgccggaa ctggaggaag tcaggcccca caagctacct ccaccagatc agacactgat
961 ccagggaaag agccaggaat ggcagtgtct tccctcttgc caaaaggcct ggggaggtga
1021 aggaagagag actttaggca agcagcccaa aggggtaaat gaaagcaaga ggctgctgcc
1081 actgacctgc tccattcaga acaagactgg atgcttctgt tgagctctcc attatgtggg
1141 acccattcct caccaaaatg aggagagaca gtgactgttc ctgccacagt ccttcccagt
1201 ctaacactat tcctgggctg catgatattc ccctgggagc aaagtgacag gcacttagat
1261 gcagcatttc accactcatg ctactaatca tctacctgct actactgtaa accatggttc
1321 cagcagcctg ttccacaccc ccacaccatc aggatagcac agggaaactg tagtttaagt
1381 ggcaaataaa aacatttgca tcaaaaaaaa aaaaaaaaaa aa
//