LOCUS NM_213030 3485 bp mRNA linear VRT 16-SEP-2024
DEFINITION Danio rerio tubulin, alpha 2 (tuba2), mRNA.
ACCESSION NM_213030
VERSION NM_213030.1
KEYWORDS RefSeq.
SOURCE Danio rerio (zebrafish)
ORGANISM Danio rerio
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE 1 (bases 1 to 3485)
AUTHORS Venditti,M., Pedalino,C., Rosello,M., Fasano,G., Serafini,M.,
Revenu,C., Del Bene,F., Tartaglia,M. and Lauri,A.
TITLE A minimally invasive fin scratching protocol for fast genotyping
and early selection of zebrafish embryos
JOURNAL Sci Rep 12 (1), 22597 (2022)
PUBMED 36585409
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 3485)
AUTHORS Itoh,T., Inoue,S., Sun,X., Kusuda,R., Hibi,M. and Shimizu,T.
TITLE Cfdp1 controls the cell cycle and neural differentiation in the
zebrafish cerebellum and retina
JOURNAL Dev Dyn 250 (11), 1618-1633 (2021)
PUBMED 33987914
REFERENCE 3 (bases 1 to 3485)
AUTHORS Spreafico,M., Cafora,M., Bragato,C., Capitanio,D., Marasca,F.,
Bodega,B., De Palma,C., Mora,M., Gelfi,C., Marozzi,A. and
Pistocchi,A.
TITLE Targeting HDAC8 to ameliorate skeletal muscle differentiation in
Duchenne muscular dystrophy
JOURNAL Pharmacol Res 170, 105750 (2021)
PUBMED 34214631
REFERENCE 4 (bases 1 to 3485)
AUTHORS Saddala,M.S., Lennikov,A., Bouras,A. and Huang,H.
TITLE RNA-Seq reveals differential expression profiles and functional
annotation of genes involved in retinal degeneration in Pde6c
mutant Danio rerio
JOURNAL BMC Genomics 21 (1), 132 (2020)
PUBMED 32033529
REMARK Publication Status: Online-Only
REFERENCE 5 (bases 1 to 3485)
AUTHORS Fei,Z., Bae,K., Parent,S.E., Wan,H., Goodwin,K., Theisen,U.,
Tanentzapf,G. and Bruce,A.E.E.
TITLE A cargo model of yolk syncytial nuclear migration during zebrafish
epiboly
JOURNAL Development 146 (1) (2019)
PUBMED 30509968
REMARK Publication Status: Online-Only
REFERENCE 6 (bases 1 to 3485)
AUTHORS Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
TITLE RFX transcription factors are essential for hearing in mice
JOURNAL Nat Commun 6, 8549 (2015)
PUBMED 26469318
REMARK Publication Status: Online-Only
REFERENCE 7 (bases 1 to 3485)
AUTHORS Huang,Q. and Huang,H.Q.
TITLE Alterations of protein profile in zebrafish liver cells exposed to
methyl parathion: a membrane proteomics approach
JOURNAL Chemosphere 87 (1), 68-76 (2012)
PUBMED 22182705
REFERENCE 8 (bases 1 to 3485)
AUTHORS Asakawa,K. and Kawakami,K.
TITLE A transgenic zebrafish for monitoring in vivo microtubule
structures
JOURNAL Dev Dyn 239 (10), 2695-2699 (2010)
PUBMED 20737511
REFERENCE 9 (bases 1 to 3485)
AUTHORS Singh,S.K., Sundaram,C.S., Shanbhag,S. and Idris,M.M.
TITLE Proteomic profile of zebrafish brain based on two-dimensional gel
electrophoresis matrix-assisted laser desorption/ionization MS/MS
analysis
JOURNAL Zebrafish 7 (2), 169-177 (2010)
PUBMED 20528263
REFERENCE 10 (bases 1 to 3485)
AUTHORS Greiling,T.M., Houck,S.A. and Clark,J.I.
TITLE The zebrafish lens proteome during development and aging
JOURNAL Mol Vis 15, 2313-2325 (2009)
PUBMED 19936306
REMARK Publication Status: Online-Only
COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final
NCBI review. The reference sequence was derived from BC060904.1.
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: CK709103.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA4476799 [ECO:0000348]
##Evidence-Data-END##
FEATURES Location/Qualifiers
source 1..3485
/organism="Danio rerio"
/mol_type="mRNA"
/strain="wild type"
/db_xref="taxon:7955"
/chromosome="11"
/map="11"
gene 1..3485
/gene="tuba2"
/gene_synonym="zgc:73108"
/note="tubulin, alpha 2"
/db_xref="GeneID:406303"
/db_xref="ZFIN:ZDB-GENE-040426-1970"
exon 1..77
/gene="tuba2"
/gene_synonym="zgc:73108"
/inference="alignment:Splign:2.1.0"
misc_feature 36..38
/gene="tuba2"
/gene_synonym="zgc:73108"
/note="upstream in-frame stop codon"
CDS 75..1430
/gene="tuba2"
/gene_synonym="zgc:73108"
/codon_start=1
/product="tubulin, alpha 2"
/protein_id="NP_998195.1"
/db_xref="GeneID:406303"
/db_xref="ZFIN:ZDB-GENE-040426-1970"
/translation="MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGG
GDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYSQLFHPEQLITGKEDAANN
YARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVD
YGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLD
IDRPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVI
SAEKACHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNVAIAA
IKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLARVQRAVCMLSNTTAIAEAWARLD
HKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEE
Y"
exon 78..300
/gene="tuba2"
/gene_synonym="zgc:73108"
/inference="alignment:Splign:2.1.0"
exon 301..449
/gene="tuba2"
/gene_synonym="zgc:73108"
/inference="alignment:Splign:2.1.0"
exon 450..3470
/gene="tuba2"
/gene_synonym="zgc:73108"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 ctcatagcga cgtctcatcc tccatcttct ctgaatagtg catctgcaca cctacatctg
61 tgcaaaaccg caaaatgcgt gagtgtatct ccatccatgt gggtcaagct ggtgtccaga
121 tcggcaatgc ctgctgggaa ctttactgtc ttgagcatgg gatccagccg gatggacaga
181 tgcccagcga taagacggtt ggcggaggag acgattcctt caacactttc ttcagcgaga
241 ccggagcggg caaacatgtg ccaagagctg tgttcgtcga tctggagccc actgtgattg
301 atgaggttcg cactggaact tacagccaac ttttccaccc tgagcagctg atcactggaa
361 aggaggatgc agcaaacaac tatgcccgcg gccattacac tatcggaaaa gaaatcatcg
421 atctcgttct tgacaggatt cgcaaactgg ccgaccagtg cactggactc caaggcttct
481 tggttttcca cagctttgga ggaggaaccg gttccggctt cacctcttta ctgatggagc
541 gcctctctgt cgactatggc aagaaatcca agctggagtt ctccatctat ccggctccgc
601 aggtgtctac agcagtggtg gagccctaca actccatcct caccacccac accaccctgg
661 agcactcgga ctgtgctttc atggtggaca acgaggccat ctacgacatc tgccgcagaa
721 acctggacat cgaccgccca acatacacca acctcaacag gctaataagc caaatcgtgt
781 cttcaatcac agcttccttg agattcgatg gcgcgctcaa tgttgacctc acagagttcc
841 agaccaactt ggtgccatat ccacgtattc atttcccact ggcgacgtat gctccagtga
901 tttctgctga gaaagcatgc cacgagcagc tttcagtgtc tgagatcact aatgcatgct
961 ttgagccggc taatcagatg gtgaaatgtg acccgcgcca tggtaaatac atggcctgct
1021 gtcttctgta ccgcggagat gtcgtaccca aagatgtaaa tgttgctatc gccgcaatca
1081 agaccaagcg cagtattcaa tttgtggact ggtgtccgac tggtttcaag gttggcatca
1141 attatcagcc tcccactgtt gtcccgggtg gagatttggc aagagttcag cgtgccgtct
1201 gcatgttgag caacaccact gctattgccg aagcctgggc taggcttgat cacaagtttg
1261 acctgatgta tgctaaacgt gcctttgtgc actggtacgt aggtgaagga atggaggagg
1321 gcgagttctc ggaggccaga gaggacatgg ctgctttgga gaaagattac gaggaagtcg
1381 gtgtagattc agtggaagga gaaggagaag aggaaggtga ggagtattag atttggtcca
1441 cttctctgtg gaataaacag ggttcccacg cttcttgaag gtctcattga aattaaaaag
1501 aacgtttttt ttagatgtta gtaacagtat tgttaatttt agggatattt ataggctagt
1561 gcgctccaaa atttgtgatt ataaaaaaac aatataaaca ggtaaaactt ggtgtttgtc
1621 actttcaccc aaatggatta aggatttatt ctgacatcgc ctcatgcttc agttccttaa
1681 atcttctgac caataaaatg ctcttaagaa tctgacatgc cccaccccct tcttctcatt
1741 tgcttttcat ttgatgcact tgagcttaaa cactctcact ggcagagctg tgataaaaca
1801 aaatgctatt ggctgttttt aaaaaaaatc agaggagcta cttttggtta agattgtcaa
1861 acatcgaata aaaaattcaa agcacttcac gggaccttta aaagtgcttg attttcagac
1921 acatggattc aaggcgtgga aagaccttaa aaacaaacac aggtccttaa caagtgcttg
1981 aattaatttt atttcgaaaa attttactta attgtcaaaa gcagaatgaa agaaactgag
2041 aaatttttaa tcctaaattt aacacttgta caataacact gacaaataat gcacatttga
2101 actgtatttc acagtatcga attgaacaaa tttgatcaaa tttctttaaa cacgactgtt
2161 taaaacggta aaaatgtttg gaaattacct aattaattaa ttgagtttta atgtaaatat
2221 taagtgtaag tgaaatgtta agtacaccac agactactgg tgctacatat gctggccata
2281 tctgtcaaca ttgggataaa aatacgggat ccgtaatgct tcaaatccaa atgatagaat
2341 acatagcaaa cattagaaaa ctaaaaataa aataaaaggt ttagcctatt aaaatcaata
2401 tttacaaata ttgattaaag ttactctagt tatttagtat tgagcagcga atgtctcatt
2461 ttgatcactg tcactttaag aatccacaga tctataatga aagcatgtga ttacatttgt
2521 aatcaaaact catttaactc attgtttaaa aacagccaaa taccagtgtc cactttcact
2581 ccttttcaaa tcgcatgtac agtagctgat ctgggaacag tgtctttatt attagggagc
2641 gcgtctgtca gtcagcacta gacaccgtta ttgattcaga ggttgcatat gaagggcaat
2701 ggtcaacgca gagctttaat ggaaataaag taaatgcagc taatttagta ttaatttcaa
2761 cgtgctttca agccaatata aagagaaagt ataattctct ttaacagctc ttgccattaa
2821 atcccatttg agacctcctc tctgatgcta ctttaggttt tcatatatag aaaaaataaa
2881 aatatgggga aatgtgcggg atataatggt aaaatagagg agaatcccag caaaaatgga
2941 gggggttgac aggtatgcag gggtatgaat tattaaaggt gcttgattta aaattaagaa
3001 gtccttgaaa gactttaaat ctgctgttca tgaaagcgtg ggaaccctaa ataaaaacaa
3061 atagctggta gcctcttgac agattgcttc gctagctgaa gaaaatgcca agtgatgtaa
3121 tggttgtgtt tgtccctgat caacatatag caaaagcggt aacactttag tttgagtaac
3181 aattcacact attaattact ggcttagtac ctgcttatta ataagatatt aactgttata
3241 aagtgtgatc ttatttaacc cctaatccca gccaatacct aaatccaact actaacatac
3301 taactattaa taagcagcta attagtagtt tattgagctg taagtcttag ttaatggttt
3361 gttaatagcg tgaattgtac attcaaataa agtgaccgca aaagctaatt gtgaatatta
3421 ctgtgcctat tttggtgtaa agtactcaat aaaatgaacc agtaaataaa aaaaaaaaaa
3481 aaaaa
//