U.S. flag

An official website of the United States government

Danio rerio GDP-mannose pyrophosphorylase Ab (gmppab), mRNA

NCBI Reference Sequence: NM_200497.1

FASTA Graphics 

LOCUS       NM_200497               2013 bp    mRNA    linear   VRT 20-OCT-2024
DEFINITION  Danio rerio GDP-mannose pyrophosphorylase Ab (gmppab), mRNA.
ACCESSION   NM_200497 XM_697197
VERSION     NM_200497.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2013)
  AUTHORS   Zheng,L., Liu,Z., Wang,Y., Yang,F., Wang,J., Huang,W., Qin,J.,
            Tian,M., Cai,X., Liu,X., Mo,X., Gao,N. and Jia,D.
  TITLE     Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells
            maintain GDP-mannose homeostasis
  JOURNAL   Nat Struct Mol Biol 28 (5), 1-12 (2021)
   PUBMED   33986552
REFERENCE   2  (bases 1 to 2013)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2013)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC055506.1.
            
            On Jul 6, 2005 this sequence version replaced XM_697197.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC055506.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505372
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2013
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="AB"
                     /db_xref="taxon:7955"
                     /chromosome="6"
                     /map="6"
     gene            1..2013
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /note="GDP-mannose pyrophosphorylase Ab"
                     /db_xref="GeneID:393469"
                     /db_xref="ZFIN:ZDB-GENE-040426-1550"
     exon            1..272
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    227..229
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /note="upstream in-frame stop codon"
     CDS             233..1501
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /EC_number="2.7.7.13"
                     /note="GDP-mannose pyrophosphorylase A-B;
                     GTP-mannose-1-phosphate guanylyltransferase apha-B;
                     GTP-mannose-1-phosphate guanylyltransferase alpha-b;
                     mannose-1-phosphate guanyltransferase alpha-B"
                     /codon_start=1
                     /product="mannose-1-phosphate guanylyltransferase
                     regulatory subunit alpha-B"
                     /protein_id="NP_956791.1"
                     /db_xref="GeneID:393469"
                     /db_xref="ZFIN:ZDB-GENE-040426-1550"
                     /translation="MLKAIILIGGPQKGTRFRPLSFEVPKPLFPVAGVPMLQHHIEAC
                     AQVPDMKEIMLIGFYQPNDELNRFIYSAQQEFKIPIRYLQEFAALGTGGGIYHFRDQI
                     LSGGPAAFFLMNADVCSEFPLLEMLQFHRQHGENHCGVLLGTTANRTQSLNYGCIVEN
                     HETNEVLHFVEKPSTFVSDIINCGIYLFTPDIFAHIGKVFQRNQQEKIQEELTHGRQM
                     PEVVRLEQDIFTALAGQKKLFVYKTQHFWSQIKSAGSAIYASRLYLKQYHQTHPERLA
                     TNQGGTPKITGDVYIHPTANIDPSAVLGPNVSIGKGVTIGGGVRVRESIILHGAVLQD
                     HCCVLNSIVGWDSTVGKWARVEGTPSDPNPNDPYAKIDSETLFRDGGLTPSITILGCN
                     VNIPSEVIIRNSIVLPHKDLNRSFKNQIIL"
     misc_feature    236..991
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7SXP8.1);
                     Region: Substrate-binding domain.
                     /evidence=ECO:0000250|UniProtKB:Q96IJ6"
     misc_feature    1055..1498
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7SXP8.1);
                     Region: Hexapeptide repeat domain.
                     /evidence=ECO:0000250|UniProtKB:Q96IJ6"
     misc_feature    1304..1390
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /note="propagated from UniProtKB/Swiss-Prot (Q7SXP8.1);
                     Region: C-loop. /evidence=ECO:0000250|UniProtKB:Q96IJ6"
     exon            273..370
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            371..474
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            475..667
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            668..727
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            728..858
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            859..993
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1091
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            1092..1138
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1231
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            1232..1400
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1993
                     /gene="gmppab"
                     /gene_synonym="gmppa; zgc:66135"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actcacttcc gcgttactgt actgaatgga ttttatgaaa ctggtctgtt aaggttaaat
       61 tgtactagtt tgggctcgct gttgcgattt tcggaaaagt tagaagaagt gttttataga
      121 ctaaacaaaa tgtttaacta gttattttat aaacagacgt gataacaaaa actggacgtg
      181 aaataatccg cgaattaaat ttcaattcaa gtgactacat cataactgaa agatgttaaa
      241 agcgattatc ctaattgggg gtcctcaaaa aggtaccagg ttccgccccc tgtcatttga
      301 ggtgcccaaa cctcttttcc ctgtagcagg agttccaatg ctgcaacatc acattgaagc
      361 ctgtgcccaa gttcctgata tgaaggagat catgctaata ggcttttatc agcccaacga
      421 tgagctgaac cgcttcattt attctgctca gcaggagttt aaaatcccaa tcaggtacct
      481 gcaggagttt gctgctctgg gtacaggtgg tgggatctat cactttcgtg accaaatcct
      541 gtccgggggc ccggctgctt ttttcctcat gaatgcagat gtatgctcag agttcccctt
      601 gctagaaatg ctccagttcc accgtcagca tggtgaaaat cattgtggag tcctacttgg
      661 aactacagca aatcgaacac aatctctgaa ctacggctgc attgtggaaa accatgagac
      721 aaatgaggtg ctccattttg tagagaaacc cagtactttt gtaagcgaca tcatcaactg
      781 tggcatctat ttgttcaccc cagatatttt tgcccatatt gggaaagttt tccagaggaa
      841 ccaacaagag aagatccagg aagagctcac tcatggcagg cagatgccag aggtggttcg
      901 gctggaacag gacattttta cagccctagc aggacagaaa aaactctttg tctataaaac
      961 acagcacttc tggagtcaga taaagtctgc agggtcagca atatatgcta gtcgcttgta
     1021 cctcaaacag tatcatcaga ctcatccgga gagactggcc acaaaccaag gtggaacccc
     1081 caaaataaca ggagatgttt atatccatcc tactgcaaac attgatcctt ctgctgtgtt
     1141 aggtcctaat gtttccattg gcaaaggggt gacaattgga ggaggtgtaa gagtgaggga
     1201 gtccatcatt ttacatggag ccgtgttaca ggaccactgt tgtgtgttga acagtattgt
     1261 tggctgggac agcacagtgg ggaagtgggc aagagtggaa ggaactccaa gtgaccctaa
     1321 tcccaatgac ccgtatgcca agatagacag tgagactctg ttcagggacg gaggtctgac
     1381 cccatccatc accatccttg gctgcaatgt gaatattcca tcagaggtca tcattcgaaa
     1441 ctctatcgtc ttgcctcata aagatctcaa caggagcttc aaaaaccaga tcattctcta
     1501 aaagacactt ttctcttttc ttgggaataa atattgcaca atgggggatg tagaaagtat
     1561 atagtattgt ttatagttta tttttatgta atgtttaggt acttggagaa aatgtgtcta
     1621 catatggaag cagattgtat tacagtagta tagtgtaaat tatatggttg aacaactggg
     1681 gattttcctg ataaatttca ggattggata ttttgtattt aatgactctg ctgatacacc
     1741 agccttacac gcactgacac aacattagat ttgagtgtta atggttttat tcttaataac
     1801 aaatgacaca tattatacct gtattgcctt ttccacaaaa tgatgagaga ttaggtcatt
     1861 tttgtttgtc tttctttaga aaatgacaaa tttgaaggga catagtgttt ttttgggcag
     1921 aaacaaaact tttgttgttg ttgattatcg ctttattctg ttacaacagt ttattaaaat
     1981 aatcttaaca caaaaaaaaa aaaaaaaaaa aaa
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown

Customize view

Reference sequence information

  • RefSeq protein product
    See the reference protein sequence for mannose-1-phosphate guanylyltransferase regulatory subunit alpha-B (NP_956791.1).

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.