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NCBI Reference Sequence: NM_178920.4
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LOCUS NM_178920 2775 bp mRNA linear ROD 04-JUN-2024 DEFINITION Mus musculus mal, T cell differentiation protein 2 (Mal2), mRNA. ACCESSION NM_178920 VERSION NM_178920.4 KEYWORDS RefSeq; RefSeq Select. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 2775) AUTHORS Zhu,M., Jia,L., Li,F. and Jia,J. TITLE Identification of KIAA0513 and Other Hub Genes Associated With Alzheimer Disease Using Weighted Gene Coexpression Network Analysis JOURNAL Front Genet 11, 981 (2020) PUBMED 33005179 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 2775) AUTHORS Reginensi,A., Hoshi,M., Boualia,S.K., Bouchard,M., Jain,S. and McNeill,H. TITLE Yap and Taz are required for Ret-dependent urinary tract morphogenesis JOURNAL Development 142 (15), 2696-2703 (2015) PUBMED 26243870 REFERENCE 3 (bases 1 to 2775) AUTHORS Bello-Morales,R., de Marco,M.C., Aranda,J.F., Matesanz,F., Alcina,A. and Lopez-Guerrero,J.A. TITLE Characterization of the MAL2-positive compartment in oligodendrocytes JOURNAL Exp Cell Res 315 (19), 3453-3465 (2009) PUBMED 19683524 REMARK GeneRIF: after differentiation, murine oligodendrocyte precursor and human oligodendroglioma derived cell lines up-regulate the expression of MAL2 and accumulate it in an intracellular compartment, exhibiting a peri-centrosomal localization. COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC115924.11. On Oct 27, 2009 this sequence version replaced NM_178920.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK035986.1, BC113154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-272 AC115924.11 124301-124572 273-443 AC115924.11 141249-141419 444-599 AC115924.11 151346-151501 600-2775 AC115924.11 153606-155781 FEATURES Location/Qualifiers source 1..2775 /organism="Mus musculus" /mol_type="mRNA" /strain="C57BL/6" /db_xref="taxon:10090" /chromosome="15" /map="15 21.37 cM" gene 1..2775 /gene="Mal2" /note="mal, T cell differentiation protein 2" /db_xref="GeneID:105853" /db_xref="MGI:MGI:2146021" exon 1..272 /gene="Mal2" /inference="alignment:Splign:2.1.0" misc_feature 24..26 /gene="Mal2" /note="upstream in-frame stop codon" CDS 144..671 /gene="Mal2" /codon_start=1 /product="protein MAL2" /protein_id="NP_849251.1" /db_xref="CCDS:CCDS27470.1" /db_xref="GeneID:105853" /db_xref="MGI:MGI:2146021" /translation="MSAGGAVPPPPNPAVSFPAPRVTLPAGPDILRTYSGAFVCLEIV LGGLVWILVASSNVPLPLLQGWVMFVSVTAFFFSLLFLGLFLSGMVTQIDANWNFLDF VYHFIVFVFYFGAFLLEAAATSLHDLQCNTTMTVKPLLNDNQYNINVAATVFAFMTTA CYGCSLGLALRRWRP" misc_feature 243..305 /gene="Mal2" /note="propagated from UniProtKB/Swiss-Prot (Q8BI08.1); transmembrane region" misc_feature 339..401 /gene="Mal2" /note="propagated from UniProtKB/Swiss-Prot (Q8BI08.1); transmembrane region" misc_feature 447..509 /gene="Mal2" /note="propagated from UniProtKB/Swiss-Prot (Q8BI08.1); transmembrane region" misc_feature 534..536 /gene="Mal2" /note="N-linked (GlcNAc...) asparagine. /evidence=ECO:0000250; propagated from UniProtKB/Swiss-Prot (Q8BI08.1); glycosylation site" misc_feature 588..650 /gene="Mal2" /note="propagated from UniProtKB/Swiss-Prot (Q8BI08.1); transmembrane region" exon 273..443 /gene="Mal2" /inference="alignment:Splign:2.1.0" exon 444..599 /gene="Mal2" /inference="alignment:Splign:2.1.0" exon 600..2775 /gene="Mal2" /inference="alignment:Splign:2.1.0" regulatory 2751..2756 /regulatory_class="polyA_signal_sequence" /gene="Mal2" /note="hexamer: AATAAA" polyA_site 2771 /gene="Mal2" /note="major polyA site" ORIGIN 1 accctttccg cgagcagcac gcctgaaccc cacggatcgg atcggcggcg gcggcggcgg 61 cggcggccaa gcccgggagg cggcggcggg acgcgggagg cggtggcggc ggtggcggtg 121 cgcggagacg tagcagcggc agcatgtcgg ccggcggagc agtcccgccg cccccgaacc 181 ctgccgtgtc cttcccggcg ccccgggtca ccctgcccgc tggccccgac atcctaagga 241 cgtactccgg agctttcgtc tgtctggaga ttgtgcttgg aggacttgtc tggattttgg 301 ttgcttcctc caatgttcct ctacctctgc tccaaggatg ggtcatgttt gtgtcggtga 361 cagctttctt cttttcgctt ctcttcctgg gcttgttcct ctctggtatg gtgactcaga 421 ttgatgccaa ctggaacttc ctggattttg tctaccattt catagtcttt gtcttctact 481 tcggagcgtt tttactggaa gcagcggcca cctccctgca tgaccttcag tgcaacacaa 541 ccatgactgt gaagccacta ctcaacgaca accagtataa catcaacgtg gccgccacag 601 tttttgcctt catgacaaca gcttgttatg gttgcagttt gggtctggct ttgcgaagat 661 ggcgaccgta acactccttg gaaactgaca gttgtgtgct ggtttcattt gtctacttta 721 tatgtctgat cacttgggta ccatttgtcc caatataaca ttccaaacat tgttagctta 781 gtacagagag gacctcagtg caagctgtgg tttgttacat gggtgggatt ttcattttgt 841 tctgatgtta gagaagtatc ctttcctttt tcatctctcg tttcttttta aatgcatttc 901 cattgtatat tcttaaaata cacaggcact gttcacaaaa caatagtatt cctttttttt 961 ttttttggtt gagtcacccg aaccttaata atagtaaata actaaaacaa tacatctcat 1021 gcaggcttct catctaattc tatctttagt ataaaacagg aaatgataca catgtttttt 1081 ttacaaaaag gccaggtagc acatatgtag gctttaatag gccatatagc ctctgtggca 1141 attgttccat cctatgataa cataaaagca gctacagatg atgtgtaaat aaatgtctgt 1201 atcctaataa agcttatttc aaaaagggag caaaactgga tgtggtctac agaccataat 1261 tttatcaact actgccataa aaaccttagg tgttctgtgt tctattgaac taatcatgaa 1321 acctcattag acaagccaca taacatattt tgtttcatta tgcatcaatc acattgcctt 1381 tgtttaatag tcaaatatta cccttggaag gtcatataat ttctcaagct aaccccagca 1441 gagccttgga tgaagagcaa aataaggtag gaaataaact ccaaactaat gatttcctaa 1501 tagctcagca aggcactcac acgagagtac ttaagacatg atccccagag gcaattaatc 1561 actactggat ctagtatctt gctactgatg tctttctttt ggtttattta tgccatagac 1621 tgtggttgtt tggcctatgc atgaatatat aaatatttat gtatgtaaag cttttccaaa 1681 tagctctctg aagagttgaa tttttaactt cttattgttt ttgcattgct ttctgagctg 1741 aatttgagta acagattaac tataacataa agctatagat tcttacatgc tttgataata 1801 gcccagatat ctatgttgtt tttacattgg tgtcagacag gcaaaggaca tttaacacaa 1861 gagctaaaac aaaaactgga tctggctgaa tagaacagaa aacaatccta gtccacctgt 1921 atgtgtcgca ggcttggcaa cagatcatga gtgaccacag ttcccaccgc attctcatac 1981 aggccaattc cctattgttt tagtagggct gcctttggaa atggaggctt gggaattgct 2041 ctcgagctga cccatcacct aagagtgcca tgtatggttg gagtattgga ctccctggaa 2101 catagtgaaa aacatgaatg aatagcatca atgcccagtg ttcaagtgct gtttatctaa 2161 tactccccca gaagaagaac caacggggac ctcagtttgt aatacagctg aagacgagat 2221 gtatttctat atgtaggttg aagaaatcag tcttatggct ttccactcat gtcttagctc 2281 ttctaaaatg ccagacttcc ctcctgtttt tccagctcca gaccacacac tgaaaaacct 2341 gtattatgaa ttatatacta tgaagtcaca aatgtgccat aaagatacat tgtacgtgga 2401 atcactaaaa tgtagtccac tagaatttag ttgagatttt tgttttcccc caggtgtacc 2461 aagccatgct cagtgtggta ttaactcaaa tgaattcatt cagatgtatt ggtggtactt 2521 ttgtaaatgt atggcttcta ggttagcaaa aagaaaactc aaagctgact aactgtgaat 2581 acttaggtct gtagattcat tgcattctag atgttgtgag ctgagcgatg aagcacttga 2641 acaaagacga aggtgtttaa gaatctctct acgtatctta gctgtaaaaa tgaaaaagtg 2701 ttggctggtc ttaaaatctg ataaatttat tttataagtg ttatgactct aataaagtat 2761 tcatttgata acctt //
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