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PREDICTED: Homo sapiens phospholipase C beta 2 (PLCB2), transcript variant X27, mRNA

NCBI Reference Sequence: XM_054378214.1

FASTA Graphics 

LOCUS       XM_054378214            1074 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens phospholipase C beta 2 (PLCB2), transcript
            variant X27, mRNA.
ACCESSION   XM_054378214
VERSION     XM_054378214.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060939) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..1074
                     /gene="PLCB2"
                     /gene_synonym="PLC-beta-2"
                     /note="phospholipase C beta 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 11
                     ESTs, 33 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     30 samples with support for all annotated introns"
                     /db_xref="GeneID:5330"
                     /db_xref="HGNC:HGNC:9055"
                     /db_xref="MIM:604114"
     CDS             264..911
                     /gene="PLCB2"
                     /gene_synonym="PLC-beta-2"
                     /codon_start=1
                     /product="1-phosphatidylinositol 4,5-bisphosphate
                     phosphodiesterase beta-2 isoform X26"
                     /protein_id="XP_054234189.1"
                     /db_xref="GeneID:5330"
                     /db_xref="HGNC:HGNC:9055"
                     /db_xref="MIM:604114"
                     /translation="MSLLNPVLLPPKVKAYLSQGERFIKWDDETTVASPVILRVDPKG
                     YYLYWTYQSKEMEFLDITSIRDTRFGKFAKMPKSQKLRDVFNMDFPDNSFLLKTLTVV
                     SGPDMVDLTFHNFVSYKENVGKAWAEDVLALVKHPLTANASRSTFLDKILVKLKMQLN
                     SEGKIPVKNFFQMFPADRKRVEAALSACHLPKGKFRSCPSQWNSHCTKSGSEQTS"
ORIGIN      
        1 agaagcagtg accacaggcc cccatggcag gcagggcggg tgggaggagg gtgatttaca
       61 aggcagatgg gcctctggct acagctcagt cctgcactca gccagggcca ccccaggggc
      121 tataagagca actagatttc tggagcagct cggggatggg tgccatttga gcccagcttg
      181 gctccccctc ctggctggcc tccttcctgc ccttctgcct gcctgtgtct gctgagattc
      241 tgcaaagagg aacgcttggc accatgtctc tgctcaaccc tgtcctgctg ccccccaagg
      301 tgaaggccta tctgagccaa ggggagcgct tcatcaaatg ggatgatgaa actacagttg
      361 cctctccagt tatcctccgt gtggatccta agggctacta cttatactgg acgtatcaaa
      421 gtaaggagat ggagtttctg gatatcacca gcatccggga tactcgcttt gggaagtttg
      481 ccaagatgcc caagagccag aagctccggg acgtcttcaa catggacttt cctgataaca
      541 gtttcctgct gaagacactc acggtggtgt ccggcccgga catggtggac ctcaccttcc
      601 acaacttcgt ctcctacaag gagaacgtgg gcaaggcctg ggctgaggac gtactggccc
      661 tagtcaaaca tccgctgacg gccaacgcct cccgcagcac cttcctggac aagatccttg
      721 tgaagctcaa gatgcagctc aactctgaag ggaagattcc ggtgaagaac tttttccaga
      781 tgtttcctgc tgaccgcaag cgggtggaag ctgctctcag tgcctgccac ctccccaaag
      841 gcaaattccg atcctgcccc agccaatgga atagccactg tacaaaatca gggtcagagc
      901 aaaccagcta agcatgctct ctgctcagca accagggcct tgagaagtgg atgcttgggt
      961 gtccttgaag ttcttctgtc tgccttgagc ccgccttctg accaggtccc cttgaccagg
     1021 gctgggccga gtttgtggtt cttagctctg agaaggtgag ggcaggggca ataa
//
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Reference sequence information

  • RefSeq alternative splicing
    See 56 reference mRNA sequence splice variants for the PLCB2 gene.
  • RefSeq protein product
    See the reference protein sequence for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X26 (XP_054234189.1).

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