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PREDICTED: Homo sapiens TBC1 domain containing kinase (TBCK), transcript variant X6, mRNA

NCBI Reference Sequence: XM_054351275.1

FASTA Graphics 

LOCUS       XM_054351275            3988 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens TBC1 domain containing kinase (TBCK),
            transcript variant X6, mRNA.
ACCESSION   XM_054351275
VERSION     XM_054351275.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060928) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3988
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..3988
                     /gene="TBCK"
                     /gene_synonym="FERRY1; Fy-1; HSPC302; IHPRF3; TBCKL"
                     /note="TBC1 domain containing kinase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 17
                     ESTs, 158 long SRA reads, and 87% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     14 samples with support for all annotated introns"
                     /db_xref="GeneID:93627"
                     /db_xref="HGNC:HGNC:28261"
                     /db_xref="MIM:616899"
     CDS             366..2939
                     /gene="TBCK"
                     /gene_synonym="FERRY1; Fy-1; HSPC302; IHPRF3; TBCKL"
                     /codon_start=1
                     /product="TBC domain-containing protein kinase-like
                     protein isoform X2"
                     /protein_id="XP_054207250.1"
                     /db_xref="GeneID:93627"
                     /db_xref="HGNC:HGNC:28261"
                     /db_xref="MIM:616899"
                     /translation="MFPLKDAEMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQI
                     LKTITHPRLCQYVDISRGKHERLVVVAEHCERSLEDLLRERKPVSCSTVLCIAFEVLQ
                     GLQYMNKHGIVHRALSPHNILLDRKGHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPE
                     VIAQGIFKTTDHMPSKKPLPSGPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLT
                     LDCVDDTLIVLAEEHGCLDIIKELPETVIDLLNKCLTFHPSKRPTPDELMKDKVFSEV
                     SPLYTPFTKPASLFSSSLRCADLTLPEDISQLCKDINNDYLAERSIEEVYYLWCLAGG
                     DLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTVTLSLCQLRNRL
                     KDVGGEAFYPLLEDDQSNLPHSNSNNELSAAAMLPLIIREKDTEYQLNRIILFDRLLK
                     AYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPTDRQIEVD
                     IPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFNNEALA
                     YACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDLYAI
                     PWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILLF
                     SDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGRSSAPYFSAECPDP
                     PKTDLSRESIPLNDLKSEVSPRISAEDLIDLCELTVTGHFKTPSKKTKSSKPKLLVVD
                     IRNSEDFIRGHISGSINIPFSAAFTAEGELTQGPYTAMLQNFKGKVIVIVGHVAKHTA
                     E"
     polyA_site      3988
                     /gene="TBCK"
                     /gene_synonym="FERRY1; Fy-1; HSPC302; IHPRF3; TBCKL"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 ttgggtcgcg gtggctgtga gggcggaaga aaaggccagg ctgaggggag ggtagagggt
       61 gaaaagctcg gatctgtgtt tggggaaggc caggcttgcg ctcctcgccg ggttccgcga
      121 aggttaacct tggctgactt ggctcgcgag caaagggcag cgtctgagct cccggcgttc
      181 caggagtggc ctcttttgta ggagcacctg aaatgcagcg tctggtgcac taagccgtag
      241 cggcagcagc agccacagcg acagcgctgg ggccctgtgt agaagctcca tcccccttgt
      301 ctttgtgctt gcctgcgtcc ccagactcag aggcagatta tcttagaaga cctaggactc
      361 caaaaatgtt tcccctgaag gacgctgaaa tgggagcctt taccttcttt gcctcggctc
      421 tgccacatga tgtttgtgga agcaatggac ttcctctcac accaaattcc atcaaaattt
      481 tagggcgctt tcaaatcctt aaaaccatca cccatcccag actctgccag tatgtggata
      541 tttctagggg aaagcatgaa cgactagtgg tcgtggctga acattgtgaa cgtagtctgg
      601 aagacttgct tcgagaaagg aaacctgtga gctgttcaac ggttttgtgt atagcatttg
      661 aggttcttca gggcttgcag tatatgaaca aacatggtat agtacacagg gcattgtctc
      721 ctcataatat cctgttggac cgaaagggac atattaaatt ggctaaattt ggactttatc
      781 acatgacagc tcatggtgat gatgttgatt tcccaatagg gtatccctcg tacttggccc
      841 ctgaggtaat tgcacaggga attttcaaaa ccactgatca catgccaagt aaaaaaccat
      901 tgccttctgg ccccaaatca gatgtatggt ctcttggaat cattttattt gagctttgtg
      961 tgggaagaaa attatttcag agcttggata tttctgaaag actaaaattt ttgcttactt
     1021 tggattgtgt agatgacact ttaatagttc tggctgaaga gcatggttgt ttggacatta
     1081 taaaggagct tcctgaaact gtgatagatc ttttgaataa gtgccttacc ttccatcctt
     1141 ctaagaggcc aaccccagat gaattaatga aggacaaagt attcagtgag gtatcacctt
     1201 tatatacccc ctttaccaaa cctgccagtc tgttttcatc ttctctgaga tgtgctgatt
     1261 taactctgcc tgaggatatc agtcagttgt gtaaagatat aaataatgat tacctggcag
     1321 aaagatctat tgaagaagtg tattaccttt ggtgtttggc tggaggtgac ttggagaaag
     1381 agcttgtcaa caaggaaatc attcgatcca aaccacctat ctgcacactc cccaattttc
     1441 tctttgagga tggtgaaagc tttggacaag gtcgagatag aagctcgctt ttagatgata
     1501 ccactgtgac attgtcgtta tgccagctaa gaaatagatt gaaagatgtt ggtggagaag
     1561 cattttaccc attacttgaa gatgaccagt ctaatttacc tcattcaaac agcaataatg
     1621 agttgtctgc agctgccatg ctccctttaa tcatcagaga gaaggataca gagtaccaac
     1681 taaatagaat tattctcttc gacaggctgc taaaggctta tccatataaa aaaaaccaaa
     1741 tctggaaaga agcaagagtt gacattcctc ctcttatgag aggtttaacc tgggctgctc
     1801 ttctgggagt tgagggagct attcatgcca agtacgatgc aattgataaa gacactccaa
     1861 ttcctacaga tagacaaatt gaagtggata ttcctcgctg tcatcagtac gatgaactgt
     1921 tatcatcacc agaaggtcat gcaaaattta ggcgtgtatt aaaagcctgg gtagtgtctc
     1981 atcctgatct tgtgtattgg caaggtcttg actcactttg tgctccattc ctatatctaa
     2041 acttcaataa tgaagccttg gcttatgcat gtatgtctgc ttttattccc aaatacctgt
     2101 ataacttctt cttaaaagac aactcacatg taatacaaga gtatctgact gtcttctctc
     2161 agatgattgc atttcatgat ccagagctga gtaatcatct caatgagatt ggtttcattc
     2221 cagatctcta tgccatccct tggtttctta ccatgtttac tcatgtattt ccactacaca
     2281 aaattttcca cctctgggat accttactac ttgggaattc ctctttccca ttctgtattg
     2341 gagtagcaat tcttcagcag ctgcgggacc ggcttttggc taatggcttt aatgagtgta
     2401 ttcttctctt ctccgattta ccagaaattg acattgaacg ctgtgtgaga gaatctatca
     2461 acctgttttg ttggactcct aaaagtgcta cttacagaca gcatgctcaa cctccaaagc
     2521 catcttctga cagcagtgga ggcagaagtt cggcacctta tttctctgct gagtgtccag
     2581 atcctccaaa gacagatctg tcaagagaat ccatcccatt aaatgacctg aagtcagaag
     2641 tatcaccacg gatttcagca gaggacctga ttgacttgtg tgagctcaca gtgacaggcc
     2701 acttcaaaac acccagcaag aaaacaaagt ccagtaaacc aaagctcctg gtggttgaca
     2761 tccggaatag tgaagacttt attcgtggtc acatttcagg aagcatcaac attccattca
     2821 gtgctgcctt cactgcagaa ggggagctta cccagggccc ttacactgct atgctccaga
     2881 acttcaaagg gaaggtcatt gtcatcgtgg ggcatgtggc aaaacacaca gctgagtaaa
     2941 tcttgctact gctcattctt tgggtccaca ctgcctttat gagctgtaac actcaccacg
     3001 aaggtctgca gcttcactcc tgaacccatc aagaccacga acccaccggg aggaacgaac
     3061 aactccagat gtgccgcctt aagagctgta acactcactg caaaggtctg cagcttcact
     3121 catgagccag cgagaccacg aacccaccag aaggaagaaa ctccaaacac atccgaatat
     3181 cagaaggaac aaactctgga cgcgctgcct ttaagaactg taacactcac cacaagggtc
     3241 cgtggctgca ttcttgaagt cagtgagacc aagaacccac cagttccgga cacagtggga
     3301 ggtgtttggt catgggggca gatccttcgt gaatggcttg atgtcctctc catggtaata
     3361 agtgagttct cactctgtta gttcacatga gagctcgttg tttaaaagtc tggctcttcc
     3421 tcctttctct tgttcctgct catgccatgt gacatgctgg ctccctgtta ccttccacca
     3481 tgattgtaag ctttgtgagg tttcatcaga gatagatgtc agcaccatgc tttctgtaaa
     3541 acctgcaaaa ctgtgagcca gttaaccatc tttttttaat agattgccca gtctcaggta
     3601 cttctttata gcaacacaag aacaaactaa cacagataat tggtaccagg agtggggtgt
     3661 tgctgttaaa tacctgaaaa tgtggaaaca gctttggaac tgggtaatag gcagaggttg
     3721 aaagagtttg gaaggctcag aagaagacag gaaaatgagt aaaagtttga aacttcttag
     3781 agactgatta aatagttata accaaaatgc tgatagctgt atggacaata aagtccaggc
     3841 tgattaagtc ttaggtggaa atgagagagt tattgggacc tggagttaag attacccatg
     3901 ttacaccctg gcaaagaact tgacaacagt gtgttcatgt catagggatc tgagtttaaa
     3961 cttaattatg atgacaagat acctggca
//
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