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PREDICTED: Xenopus laevis E3 ubiquitin-protein ligase HUWE1-like (LOC108699996), transcript variant X7, mRNA

NCBI Reference Sequence: XM_041574913.1

FASTA Graphics 

LOCUS       XM_041574913           14436 bp    mRNA    linear   VRT 14-MAY-2021
DEFINITION  PREDICTED: Xenopus laevis E3 ubiquitin-protein ligase HUWE1-like
            (LOC108699996), transcript variant X7, mRNA.
ACCESSION   XM_041574913
VERSION     XM_041574913.1
DBLINK      BioProject: PRJNA338693
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_054386.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Xenopus laevis Annotation Release
                                           101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.6
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14436
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /strain="J_2021"
                     /db_xref="taxon:8355"
                     /chromosome="8S"
                     /sex="female"
                     /tissue_type="Erythrocytes"
                     /dev_stage="adult"
                     /collection_date="06-Jul-2016"
                     /collected_by="Jessica Lyons"
     gene            1..14436
                     /gene="LOC108699996"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 4 ESTs, 4 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 41 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:108699996"
     CDS             355..13482
                     /gene="LOC108699996"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase HUWE1-like isoform
                     X5"
                     /protein_id="XP_041430847.1"
                     /db_xref="GeneID:108699996"
                     /translation="MKVDRTKLKKTPTEAPADCRSLIDKLKVCSDEQLLLELQQIKTW
                     NIGKCELYHWVDLLDRFDGILADAGQTVENMSWMLVCDRPEREQLKALLLAVLNFTAL
                     LIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITRLASDKRTPLL
                     SRLQHLAESWGGKENGFGLAECCKDMHMLKYPPSATTLHFEFYAELGSEVKVEKRTSS
                     NTLHYIHIEQLDKISESPSEIMESLTKMYSIPKDKQMLLFTHIRLAHGFSNHKKRLQA
                     VQARLHAISILVYSNALQESANSILYNGLIEELVDVLQIADKQLMEIKAASLRTLTSI
                     VHLERTPKLSSIIDCTGTASYHGFLPVLVRNCIQAMIDPTMEPYPHQFATALFSFLYH
                     LASYDAGGEALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQSH
                     SGLSIFIYRLEHEVDLCRKECPFVIKPKIQRPANVQEGEEMETDMEVSDVAMESCPGP
                     STSSDHRPSLSTSSSSSSIVVPRTGVQCIPQRAALLKSMLNFLKKAIQDPAFSDGIRH
                     VMDGTLPTSLKHIISNAEYYGPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHA
                     LLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRR
                     RSSDPLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPSI
                     QKADGTATAPPPRTNHAAEEASSEDEEEEEVQAMQSFSTNQQSEVEPSQHVVGTEERI
                     PIPLMDYILNVMKFVESILSNNTTDDHCQEFVSQKGLLPLVTILGLPNLPIDFPTSAA
                     CQAVAGVCKSILTLSHEPKVLQEGLLQLDSILSSLDPLHRPIEAPGGSVLLRELACAG
                     NVTDATLSAQATPLLHALTAAHAYIMMFVHTCRVGQSEIRAISVNQWGSQLGLNVLNK
                     LSQLYCSLVWESTVLLSLCTPNSLPPGCEFGQADMQKLAPKEEKAATILPQGTKRPEN
                     EVEGTVASEEATGLLEGIGLDGDTLAPMETDEPNTSDAKVKPKITPAMAARIKQIKPL
                     LSASSRLGRALAELFGLLVKLCVGSPVRQRRSHHAASTTTAPTPAARSTASALTKLLT
                     KGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPYHLMLQKFLCSGGHNALFE
                     TFNWALSMGGRVSVSEGLEHIDLPDGTGEFLDAWLMLVEKMVNSTTVLESPHSLPNTK
                     LPGGQNHPQFSALRFLVVTQKAAFTCIKHLWNRKPLKVYGGRMAESMLAILCHILRGE
                     PVIRERLSKEPEGSREEEGQQDESGARREPQVNQQHLQQLMDMGFTREHALEALLNTS
                     TMEQATEYLLTHPPPLIGGGVVRDLSMSEEDQMLRAIAMSLGQDIPMEQRAELPEETA
                     RRKEEEERKAREKQEEEEAKCLEKFHDAEPLEQDELQGFTDTMLPGCFHLLDELPDTV
                     YRVCDLIMTAVKRNGADYRDMILKQVVNQVWEAADVLIKAALPLTTSDTKTVSEWISQ
                     MATLPQASNLATRILLLTLLFEELKLPCARVVETSGILNVLIKLLEVVQPCLQAAKEQ
                     KDVQTPKWITPVLLLIDFYEKTSISSKRRMQLNRYLQSNGNNWRWFDDRSGRWCSYSA
                     SNNNTIDAAWKAGETCVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPKLLK
                     GGKIGNGQELEKTLEESKEVEAKQKDDKVPDPIPVPEISSTEKEAPTDEPKVGDIVIQ
                     GLTEEMVTVLIRSCVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKSTRMILS
                     LTQSSGFNGFTPLVTLLFRHIIEDPFTLQHTMEKVVRSAATSGAGSTTSGVVSGSLGS
                     REINYILRVLGPAACRNPDIFTEVANSCIRIALPAPRGSGTASDDEFENLRIKGPNAV
                     QLVKTTPVKPSTLPVIPDTIKEVIYDMLNALAAYHAPEEVSEKSEQKSVGMNLEVSQI
                     LQDMGDEVFQQYRDLTRQGSDFDGQNSFALNARVFTADSTATETPPSGTPQGETALTP
                     EENREGIKKDKEGDRSSEDGKQKAKGSKPLLPTSSILRLLAELVRSYVGIASLIATYN
                     YTAGQSELIKEDCSVLAFVLDHLLPHTQNAEDKDTPALARLFLASLAAAGSGTDAQVA
                     LVNEVKAALGRALAMAESTEKHARLQAVMCIISTIMESCPSTSSFYSTATTKTQHNGM
                     NNIIRLFLKKGLVSDLARVPHSLDLSSPNMANTVNAALKPLETLSRIVNQPSSLFGSK
                     GTSGKNKSETDAHGTAQDPNSNQPDTGETGTEVQEEDPDASHAEVADGDIMDGETETD
                     AVVIAGQPEVLSTQEMQVETELEDLIDELLERDGAAGNRVGEDESQEDVLMDEAPNNL
                     SQVSTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQEEEEEEEDEDDQDDEE
                     GEEGDEDDDDDCSEMELDEDYPDMNASPLVRFERFDREDDLIIEFDNMFSSATDIPPS
                     PGNIPATHPLMVRHADHGSLTLGSGASTTRLAQGIGRSQRTLRQLTANTGHTIHVHYP
                     GNRQPNPPLILQRLLGPSAAADILQLSSSLPLQSRGRARLLVGNDDVHIIARSDDEML
                     DDFFHDQSTATSQAGTLSSIPTALTRWTEECKVLDAESMHDCVSVVKVPIINHLESLR
                     DEELEERREKRRKQLAEEDAKMTEKSKEEKETKEQNSQGANSKQNTPFELSLADQDGS
                     GHPENFPTAPSSAEGTPTSPEIVRLDPTLRAHPPEATLAQLPQGLPADSGTEDAGLQL
                     MSSHQEDSGPGHPSTEGDATQMELSPAPTITSLSPERAEDSDALTAVSSQLEGSPMDT
                     SSLASGPLEDGVGEIPGIVNPEQPLVVGSSIAVGQQPVEPPTTGEAQPVVSQHSDESS
                     PIAPSSELPSLRESAVTLLATDSSGILEEPLPSTSSEDEDPLAGINLPEGVDPSFLAA
                     LPEDIRREVLQNQLGIRPPSRPPPTAAPVIPPPVVANAGVTEVSPEFLAALPPAIQEE
                     VLAQQRAEQQRRELTQSITSDTPMDPVTFIQTLPSDLRRSVLEDMEESVLAVMPPDIA
                     AEAQALRREQETRQRQLMHERLFGHSSTSALSAILRSPAFTSRLSSNRGVQYTRLAVQ
                     RGNTFQMGSSSTHTRPTGSNVDSLLRLRGRLLLDHEALSCLLVLLFVDEPKLNTSRLH
                     RVLRNLCYHAQTRNWVIRSLLSILQRSSESELCIESPKTSIGGPDKRGSAKTIASHDN
                     RPLELLHKMESKNSNQLSWLSVSMDAALGCRTNIFQIQRSLGRKHTEKHAACGSTVHI
                     HPQAAPVVCRHVLDTLIQLAKVFPSHFTQQRTKECIVENSDNRERSIKLTCSPCLAPS
                     ISVGASNISTDFWDLLVKLDNMNVSRKGKTSIKSVPVSSGSEGESNQGSLEASPLGQL
                     MNMLSHSVIHRSSLLTEKLLRLLSLISIALPDNKASEMTGNPSNSITPAPAPATAPAP
                     APVPAVTVPTVVSTSIVTTVTTKSGKSPAKLNEVSIAPDNMAASGLTEKQLQLSVEVL
                     TSHSCSEEGLEDAANVLLQLSRGDPGTRDTVLKLLLSGAHHLGFTLCKQIGTLLAELR
                     EYNLEQQRRAQCEVLSPDGMPEEQPHSTKAKGKMQSSVRSLPTPPLRSRFDIAENVVI
                     VASQKRPLGGRELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAKQTSRL
                     GTASLASASSIQAAVQQLEAEADAIIQMVREGQRARRQLQTATAEGSARREEQPMDVD
                     QPSPAPQETQSAASEVSQAVEKKEEERLPELPLLSDQLSLDELWDMLGECLKELEESH
                     DQHAVLVLQPAVEAFFLVHATERESKPPVRDTRESQLSHIKDEPPPLSPAPLTPATPS
                     SLDPFFSREPSSMHISSSLPPDTQKFLRFAETHRTVLNQILRQSTTHLADGPFAVLVD
                     YIRVLDFDVKRKYFRQELERLDEGLRKEDMAVHVRRDHVFEDSYRELHRKSPEEMKNR
                     LYIVFEGEEGQDAGGLLREWYMIISREMFNPMYALFRTSPGDRVTYTINPSSHCNPNH
                     LSYFKFVGRIVAKAVYDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLL
                     ENDVSTLGYDLTFSTEVQEFGVCEVRDLKPNGANILVTEENKKEYVHLVCQMKMTGAI
                     RKQLAAFLEGFYEIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQ
                     IQWFWRALRSFDQADRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRL
                     PSAHTCFNQLDLPAYESYEKLRHMLLLAIQECSEGFGLA"
ORIGIN      
        1 ggaaggctgg ccagggacgc atcgagaaga caaggggagg ggccagctgg tgtcatcgcg
       61 agacttggtg ccgcggatct agcgcttagg agtcctggag tcagtgaggg tagctttggt
      121 ggggaaatag ctgttttaag atggcggaga cagccggagc tcggggttaa actcaccgac
      181 cgagaagttg ccaagactcc atcttctgag tttttgcctt gcgaattggg aggctaacct
      241 tgtatattct gagctacact tgaggccttt cgactgtctt tcaatgcact tctcctcatc
      301 ccctacgtac cttgctagtt ccagctagtg gaaggaaatc agtctgtttt gactatgaaa
      361 gtggacagaa cgaagttgaa aaagacgcca acagaggcgc ctgcagattg caggtctctg
      421 atagacaaac tgaaagtctg cagtgatgaa cagcttttgc tggagctaca gcaaatcaaa
      481 acatggaaca ttggaaagtg cgagctttat cactgggtag acttattaga tcgcttcgat
      541 ggcattctgg cagatgctgg acaaacggta gagaacatgt cctggatgct ggtgtgcgac
      601 agacccgaga gggaacagct aaaggctctt ttgctagcag tgttaaactt cactgctttg
      661 cttatcgaat acagcttttc acggcacttg tacagttcca tcgagcacct tacaactctg
      721 cttgcatctt ctgacatgca agttgttctg gctgtgctaa atcttctcta cgtctttagt
      781 aagaggtcca attacatcac acgactggcc tctgacaaga gaacgccttt attgtctagg
      841 cttcagcacc ttgcagagag ctggggaggc aaagagaatg gctttggact tgctgaatgt
      901 tgtaaagata tgcacatgtt gaaataccca cctagcgcca caactttgca ctttgagttt
      961 tatgcagaac ttgggtccga ggtgaaagtt gaaaaaagga catccagtaa cacactacat
     1021 tatatacaca ttgaacaact agataagatt tctgaaagtc cctctgagat aatggaatct
     1081 ctcaccaaaa tgtacagcat tcccaaggat aaacagatgc ttttgtttac acacatacgg
     1141 ctagcacatg gcttttctaa tcacaagaag cgactacaag cagtgcaggc tagactgcat
     1201 gccatctcaa tactagtata ttctaatgcc ttgcaagagt ctgcaaacag catcctctac
     1261 aatggattga tagaggagtt agtggatgta ctgcaaatag cagacaagca actcatggaa
     1321 attaaagctg catcactaag gactttgaca tctattgtac acttagaaag aacaccaaag
     1381 ctgagcagta ttattgactg cactggaact gcctcttacc atggattttt accagtctta
     1441 gtccgaaact gcattcaagc tatgatagac ccaaccatgg agccataccc tcatcagttt
     1501 gcaacagctc ttttttcctt cttgtatcac ctagccagtt atgatgctgg tggagaagct
     1561 cttgtttcct gtggaatgat ggaagcactc cttaaggtga tcaagttcct tggcgatgaa
     1621 caggaccaga ttacgtttgt gactcgagct gtgagggtcg ttgatcttat tacaaactta
     1681 gatatggcag ctttccagtc ccacagtggg ttgtccattt ttatttacag actagagcat
     1741 gaagttgacc tatgcagaaa agagtgccct tttgttatca agccaaaaat acagcgtccc
     1801 gccaatgttc aggaagggga ggagatggag acagatatgg aagtatcaga tgtagctatg
     1861 gagagctgtc ctggtccttc tacttccagc gatcatcgtc cttctctgag cacaagtagt
     1921 agctcgagta gtatagtggt cccacgaaca ggtgtgcagt gcattcctca aagggcagct
     1981 ctattaaaat caatgcttaa tttcttgaaa aaagcaatcc aagacccagc tttctcagat
     2041 ggcatccgcc atgttatgga tggaactctt cctacatcgc tgaaacacat aatcagtaat
     2101 gccgaatact atggcccttc tttgttcctg cttgctactg aagtggtgac agtatttgtt
     2161 ttccaagagc catcactgct gtcttctctc caggacaatg gtttaacaga tgtgatgctt
     2221 catgctctcc ttataaaaga tgttcctgct acccgagaag ttcttggatc ccttcctaat
     2281 gtcttcagtg ctctctgttt aaatgcccga ggtctacagt cttttgtgca atgccaaccc
     2341 tttgagcgac tattcaaagt gttgctctct cctgattacc ttcctgctat gaggagacga
     2401 aggagctcag accctctagg cgatacagcc tctaacctgg gcagtgctgt tgatgaactg
     2461 atgaggcacc agcccacatt aaaaacagac gctacaactg ccatcattaa gctcttagaa
     2521 gagatatgta accttggtag ggacccaaaa tacatctgtc agaagccatc tattcagaag
     2581 gctgacggca cagctactgc tcctccacca cgtaccaacc atgcagcaga ggaggcttca
     2641 agtgaggatg aagaggagga ggaggttcaa gcaatgcaga gtttcagcac aaatcaacaa
     2701 agtgaagttg agcccagcca gcatgttgtt ggcacagagg agaggattcc tattcctcta
     2761 atggattata ttctcaatgt gatgaagttt gtggaatcaa ttctaagtaa caacacaact
     2821 gatgatcact gccaggaatt tgtcagtcag aagggtctcc ttccacttgt caccatcctt
     2881 gggcttccca acctacctat tgacttccct acctctgctg cctgccaagc tgtggcaggc
     2941 gtctgcaaat ccattttgac actctctcat gagccaaaag ttctccaaga aggacttctt
     3001 cagctggatt caatcctctc ttctcttgat ccacttcatc ggcccattga ggctccaggt
     3061 ggctcagtac tgctgcggga gttggcatgt gctgggaatg tgacagatgc tactctttcg
     3121 gcccaagcaa ctccattact gcacgctctc actgcagccc atgcctatat catgatgttt
     3181 gtgcatacgt gcagggttgg acagagtgaa attcgtgcca tctctgtgaa ccaatggggc
     3241 tcacaactgg gtcttaatgt tttgaacaag ttgagccaac tctactgctc ccttgtatgg
     3301 gaaagtactg ttttgctgtc actttgtact cctaacagct tgcctcctgg gtgtgagttt
     3361 ggccaagcag acatgcagaa attagcccca aaagaggaaa aggcagccac tattttaccc
     3421 caaggaacaa aaaggcctga aaatgaggtt gaaggcacag ttgccagtga ggaagctact
     3481 ggcctgcttg aaggaattgg gctggatgga gatacattag ctccaatgga aactgatgaa
     3541 cccaacactt ctgatgcaaa ggtcaaacca aaaattaccc cagctatggc agccagaatc
     3601 aagcaaataa aaccattact atcagcttct tctaggttgg gccgagcttt ggcagaactg
     3661 tttggattgc ttgtcaaact gtgtgtaggt tctcctgttc ggcaaaggag gagtcaccat
     3721 gctgccagca ctaccacagc ccctacacca gctgctcgct ccacagcgtc tgccctcacc
     3781 aaactgctca caaaagggct ttcttggcag cctcctcctt acacccctac ccctaggttc
     3841 agattgacct tttttatctg ttccgttggg ttcacatccc ccatgctgtt tgatgaaagg
     3901 aaatatccat atcacctcat gctgcagaaa tttctctgct ctggtgggca caatgcactc
     3961 tttgagactt ttaactgggc actttcaatg ggtggaagag tttctgtttc tgagggcctg
     4021 gaacacattg atcttcctga tggtactgga gaatttttag atgcttggct catgttagtg
     4081 gaaaagatgg tgaattctac cacagtgctg gaatcgcctc attctcttcc caatacaaag
     4141 ttacccggag ggcagaatca cccacagttc agtgcattac gcttccttgt ggttacacaa
     4201 aaggcagctt ttacctgtat caaacacctc tggaatcgaa aacctttgaa agtgtatggc
     4261 ggacgtatgg cagaatcaat gcttgcaatc ctgtgtcata ttctccgtgg tgagccagta
     4321 attcgtgaac gtttgagcaa agagccagag ggtagccgtg aagaagaggg tcagcaggat
     4381 gaaagtggag caagaaggga gcctcaagta aaccagcagc atcttcagca gctgatggat
     4441 atggggttca cacgggaaca tgctttagag gctctgctta acactagtac tatggagcag
     4501 gccactgaat acctcctcac ccaccctcca cctcttattg gcgggggtgt tgtacgggac
     4561 ttaagtatgt cagaggaaga tcagatgctg agagccattg ccatgtcgct gggacaagat
     4621 atccctatgg aacagagggc agaactgccc gaggaaactg ctcggcggaa agaagaggag
     4681 gagcgcaagg cacgagaaaa acaagaggaa gaggaggcga aatgcctgga aaagtttcat
     4741 gatgcagagc ccctggaaca ggatgagctt caaggcttca cagacaccat gctccctggc
     4801 tgcttccact tgctcgatga gttgccagac acagtctata gagtgtgtga tcttataatg
     4861 actgccgtaa agcgcaatgg ggcagactat cgagacatga ttctaaagca agtggttaac
     4921 caggtatggg aagctgctga tgttcttatt aaagctgctc tgccgctgac cacaagtgac
     4981 acaaaaactg tttcagagtg gatcagccaa atggccacac ttcctcaagc ttctaacttg
     5041 gccactcgca tccttttgct caccttgctg tttgaggagc taaaactgcc atgcgctcga
     5101 gttgttgaaa caagtggaat acttaatgtg ctaattaagc tgctcgaagt ggttcagcca
     5161 tgtttgcagg cagccaagga gcaaaaggat gttcagaccc caaagtggat tacaccggtc
     5221 ctccttttaa tagatttcta tgagaagacc tccatttcct ccaaaagaag aatgcaactg
     5281 aataggtacc ttcagtcaaa tggaaacaac tggcggtggt ttgatgatcg ttctggccgg
     5341 tggtgcagct acagtgctag taacaacaac acaattgatg cagcctggaa agcaggagag
     5401 acttgtgtgc gattcacagc tggccgtcga agatatactg tgcaatttac cacaatggtt
     5461 caggtaaatg aagagactgg caacagaaga cctgttatgc tgactctgtt gcgtgttccg
     5521 aaactgttaa agggtggaaa aattggaaat ggacaggagc tagaaaagac acttgaggag
     5581 tcaaaggaag tggaggcaaa gcagaaagat gataaagtgc ctgatcctat tccagttcca
     5641 gaaatctctt ccactgaaaa agaggcccca actgatgagc ccaaagtggg agacatagta
     5701 atccagggtc tgactgaaga gatggtgact gtcctaatac gttcctgtgt gagcatgctt
     5761 ggtgttccag ttgatccaga tactctacat gcaaccttgc gtctctgtct gcgtctcaca
     5821 cgtgaccaca aatatgccat gatgtttgca gagctgaaga gcactcgaat gatccttagc
     5881 ttaactcaaa gctcaggatt caatggcttt actccccttg taacgctcct ctttaggcac
     5941 atcatagagg atccattcac cctccagcac accatggaaa aggttgtacg gtctgcagca
     6001 actagtggtg cagggagcac cacctctggg gttgtgtctg gaagcctagg ttctcgtgag
     6061 atcaactaca tactcagagt actgggccca gcagcctgtc gaaaccctga cattttcact
     6121 gaagtggcaa acagttgcat tcgtattgct ctccctgcac ctcgtggatc tggaactgcc
     6181 tctgatgatg agtttgagaa ccttcggatc aaaggtccca acgcagtaca gttagttaaa
     6241 accacccctg taaagccttc caccttgcca gtcatccctg atacaattaa ggaagtcatc
     6301 tatgacatgc tgaatgcact ggcagcttac catgctcctg aggaagtatc tgaaaagtca
     6361 gagcaaaaat ctgttggcat gaacctggaa gtcagtcaga tcctacaaga catgggtgat
     6421 gaagttttcc agcaatatcg ggatttaacc agacaaggaa gtgactttga tggtcagaac
     6481 agtttcgccc tcaatgcgcg tgtctttacc gctgacagta cagccaccga aacacctccg
     6541 tctggaacac ctcaaggtga aacggcctta acacctgaag aaaacagaga agggataaag
     6601 aaggataaag aaggagaccg tagttcagaa gatggaaagc aaaaagcaaa gggtagcaag
     6661 cccttgttgc ctacctcttc catccttcgg ttacttgcgg aacttgtcag gtcctatgtt
     6721 gggatagcct cgctaattgc cacttacaat tacacggcag gacaatctga actaattaaa
     6781 gaggattgta gtgtattggc atttgtgcta gatcacctcc taccccacac acagaatgca
     6841 gaggacaagg acacgccagc cttggcccgc ctcttcttag ccagccttgc tgcagcaggt
     6901 agtggcactg atgcccaggt tgcacttgtg aatgaagtaa aggcagctct tggcagagca
     6961 ctagcaatgg ctgagagcac agagaagcat gctagattgc aggctgtaat gtgcataatc
     7021 agtaccatta tggagtcatg tccatccacc tccagtttct acagcactgc aaccaccaaa
     7081 acccagcaca atggcatgaa caatattatc agactctttc tgaagaaggg gttggttagt
     7141 gacttggctc gggttcctca cagccttgat ttatccagtc caaatatggc aaacacagtg
     7201 aatgcagcac tgaagccact cgagacactg tctcgtattg tcaatcagcc cagcagccta
     7261 tttggaagca aaggaacttc aggaaagaat aaatctgaga cagatgccca tggaacagcc
     7321 caggatccaa atagtaacca gccagataca ggtgaaacag gaacagaagt gcaggaagag
     7381 gacccagatg cttctcatgc tgaagtagct gatggagaca tcatggatgg agagacagag
     7441 acagatgctg tggttattgc tggccaacct gaggtccttt ctacacaaga gatgcaggtg
     7501 gagactgagc ttgaagacct gattgatgaa cttcttgaaa gggatggtgc tgcaggtaac
     7561 agagttgggg aagatgaatc acaggaagat gtgctgatgg atgaggctcc taacaacctc
     7621 agccaagttt ctactcttca ggctaaccga gaagattcta tgaacatcct agacccagag
     7681 gatgaggaag agcataccca agaagaggac agtagtggca gcaatgaaga cgaagatgac
     7741 agccaggaag aagaggagga agaggaagat gaggacgatc aggatgatga ggaaggcgaa
     7801 gaaggggatg aggatgatga tgatgactgt tcagagatgg aactggatga ggattatcca
     7861 gacatgaatg cttcacctct tgtacgcttt gagcgttttg accgggaaga tgatttaatc
     7921 attgagtttg ataatatgtt ttccagtgca actgacatcc ctccatcgcc tggtaacata
     7981 cctgccacac accctctgat ggtgcgacat gctgatcatg gttctctaac tcttggcagt
     8041 ggtgcttcca ctactcgcct ggcacagggc atcgggcgca gtcaaagaac actcagacag
     8101 ctcacagcca acactggtca cacgatacat gttcattatc ctggcaatag gcagccaaat
     8161 ccacctttaa tcctccagag gttgctgggg ccctcagccg ctgctgacat cttacaacta
     8221 agcagcagtc ttcctctgca aagtcgtggc cgagcacgtc tacttgttgg caatgatgat
     8281 gtccacatca tagcccgctc tgatgacgag atgcttgatg actttttcca tgatcagagt
     8341 acagccacaa gtcaggctgg cacactttcc agcattccaa ctgctctgac ccgatggact
     8401 gaggagtgta aggttctgga tgctgagagt atgcatgact gtgtatccgt ggtcaaagtc
     8461 ccaatcatta atcatctgga gtctttgcgg gatgaggaac ttgaggaacg cagggaaaaa
     8521 agaagaaaac agctagcaga agaggatgct aagatgaccg agaaatccaa ggaggagaag
     8581 gaaacaaagg agcaaaactc tcagggtgcc aattcaaagc agaatacccc atttgagctg
     8641 agccttgcag atcaagatgg aagtggtcat cctgaaaatt tccccactgc cccttcttct
     8701 gcagagggaa ccccaacaag tcctgaaatt gttcgtttag atcccaccct aagggctcat
     8761 cctcctgagg ctactttggc tcagctgcct caaggtcttc ctgctgattc aggcacagag
     8821 gatgctgggc tacaactcat gtcatctcac caagaggact ctggaccagg acatcctagc
     8881 acagaggggg atgccacgca aatggagctc tcgccagcac ccactataac ctctttgtca
     8941 ccagagcgag cagaggattc agatgccttg acagctgtta gtagccaact agagggctcc
     9001 cccatggaca ctagcagtct tgcctctggg cccttagagg atggagtagg ggagattcct
     9061 ggaattgtca atccggagca gcctcttgtg gttggcagca gcattgcagt tggacagcag
     9121 ccagtggaac caccaaccac aggtgaagcc caaccagtag tttctcaaca cagtgatgag
     9181 agctcaccca ttgccccttc ctctgagttg ccttccttaa gagagagtgc ggtgaccttg
     9241 ttagctacag attctagtgg tatcctagaa gaacctttgc cttcaacaag tagtgaagac
     9301 gaagacccat tagcaggtat aaatcttcca gagggtgtgg atccttcttt ccttgcagct
     9361 cttcctgaag atatccgcag agaggtgctg caaaatcagt tgggcataag gccaccatcc
     9421 cgacctccac caactgctgc cccggtcatt ccccctcctg ttgttgctaa tgcaggtgtc
     9481 acggaggtca gccctgaatt cctggctgct ttgccaccag ccattcagga agaggtccta
     9541 gcacagcagc gagcagaaca gcagagacgg gagcttactc agagcatcac gtctgatacc
     9601 ccaatggatc cggtgacttt tattcagacg ctaccttctg atctacgacg tagtgtatta
     9661 gaagacatgg aggaaagtgt tttagctgtg atgccacctg atattgctgc agaggcacag
     9721 gcactgcggc gagagcaaga aactcgtcag aggcagctaa tgcatgagcg attgtttgga
     9781 catagcagca cttctgcgct ctctgctatc ctcagaagtc ctgcttttac gagtcgtttg
     9841 agtagtaaca gaggtgttca gtatacaagg ttggctgtgc agagagggaa cactttccaa
     9901 atgggaagca gcagtacaca taccaggcca actgggagta atgttgacag cctgctacgg
     9961 ttacgaggcc gtctattgct tgatcatgaa gccctctcct gtctgcttgt cctactgttt
    10021 gttgatgaac cgaagctaaa cactagtcgt ttgcaccgtg tactacgcaa cctttgctac
    10081 catgcacaaa cacggaactg ggtcattagg agcttgttgt ctatattgca gcgcagcagt
    10141 gaaagtgagc tttgtattga gagcccaaag acttctattg gaggccctga taaaaggggt
    10201 agtgcaaaaa ccattgcaag tcatgacaac cgccctttag aattgctgca taagatggaa
    10261 tcaaaaaatt ccaaccagct ctcctggcta tctgtatcca tggatgctgc tcttggctgt
    10321 cgtacaaaca tcttccaaat ccaaaggtca ctaggacgca aacacacaga aaagcatgca
    10381 gcctgtggtt ctactgtcca cattcatccc caagcagccc ctgtagtgtg taggcatgtt
    10441 ctggacacac tcatacagtt ggcaaaggtt tttcccagtc atttcacaca gcagcggacc
    10501 aaagagtgta ttgtggaaaa cagtgacaac agggagcgga gtataaagct tacttgtagt
    10561 ccatgtcttg caccttccat tagtgtcggg gcaagcaaca tctccacaga tttctgggac
    10621 ttactagtca agctagacaa catgaacgtg agccggaagg ggaaaacttc cataaaatct
    10681 gtgccagtga gctctgggtc tgaaggcgag agcaatcagg gcagcctgga ggcctcccca
    10741 ttaggacagc tcatgaatat gctctctcat tctgttattc atcgcagttc gctgcttact
    10801 gaaaagctgc tgagacttct ttcccttatc tctattgctc tccctgataa taaggcttct
    10861 gagatgacag gcaatccgag caattctatc accccagcac ctgcacctgc aactgcacca
    10921 gcccctgcac ctgtacctgc tgtaacagtt ccgactgttg tgagcacaag catagtgaca
    10981 actgttacta caaaaagtgg aaagtctcct gcaaaattaa atgaggtcag cattgcacca
    11041 gataacatgg cagcttctgg tctcactgag aaacagctgc agttgtctgt tgaggtgctg
    11101 acatcacact cctgttcaga ggaaggactg gaagatgccg ccaatgttct actgcagctc
    11161 tccagaggcg accctggtac acgggacact gtattgaaac ttctgcttag cggagcacat
    11221 cacttggggt ttaccctctg caaacagata ggtactctat tagcagagct ccgggaatat
    11281 aacctagagc agcagcgacg tgcacaatgt gaagttcttt ctccagatgg tatgcctgag
    11341 gagcaacccc acagcacaaa ggcaaagggc aaaatgcaga gcagtgtcag gtctctcccc
    11401 actccacctc tgcgatccag gtttgacatt gcagagaatg tagtgattgt ggcttcccaa
    11461 aagcgtccac tgggaggaag agagttgcag cttccctcaa tgtctatgct aacgtcaaag
    11521 acttccacac aaaaattctt ccttcgagtg ctgcaagtta tcatccagct tagagatgac
    11581 actcgtagag ccaacaagaa ggccaagcag accagcagat taggcactgc cagtctggct
    11641 tcggctagca gcatccaggc agctgtgcag cagctggagg ctgaggctga tgccattata
    11701 caaatggtac gtgagggtca aagggcgcgg agacagctgc aaactgcaac ggcagagggt
    11761 tctgctcgca gggaagagca acctatggat gttgaccagc cttcacctgc tccacaggag
    11821 actcagtcag ctgcttctga agtttctcag gctgttgaga agaaagagga ggagaggctg
    11881 ccagagttac cactgttaag tgatcagctg agtttagatg agctgtggga catgctggga
    11941 gagtgcctga aggaacttga ggaatctcat gaccagcatg ctgtattagt gttacagcca
    12001 gctgtagaag cctttttcct tgttcatgca acagagcggg agagcaagcc tcctgtgcgg
    12061 gatactcggg aaagccagtt atctcacatt aaggatgaac cgcctccact ttctcctgca
    12121 cccctcactc cagccacacc ttcttccttg gatcctttct tctctcgtga accttcatct
    12181 atgcacattt cctctagttt gcctcctgac actcagaagt ttttacggtt tgctgagact
    12241 catcgaactg tactaaatca aatccttcgc cagtccacca cacacctagc tgatgggccc
    12301 tttgctgttc ttgtagacta tatcagagtc cttgactttg atgtcaaacg caaatatttc
    12361 cgacaggagt tggagcgcct ggatgaaggg ctacgtaaag aagatatggc agtgcatgta
    12421 cggcgtgatc acgtgtttga ggactcctac cgggagctgc accgcaaatc ccctgaagaa
    12481 atgaagaata gattatacat agtgtttgag ggagaagaag ggcaggatgc aggtgggctg
    12541 cttcgtgagt ggtacatgat tatctccagg gagatgttca atccaatgta tgctctcttc
    12601 cgcacttccc ctggtgaccg ggtcacctac actattaatc cttcctccca ctgtaaccct
    12661 aaccacctca gttacttcaa gttcgttggt cggatagtgg ccaaagctgt gtatgacaac
    12721 cggctactgg agtgctactt cactaggtcc ttctataagc atatactggg caagtctgtc
    12781 agatacactg acatggagag tgaagattat cacttctatc aaggtctggt atacttgctt
    12841 gaaaatgatg tctccacact gggatacgat ctgactttca gcactgaggt tcaagaattt
    12901 ggtgtttgtg aagtccgcga ccttaaacca aatggtgcaa acattctggt aacagaagaa
    12961 aacaaaaagg agtatgttca tcttgtgtgc cagatgaaaa tgacaggtgc aatacgcaag
    13021 caattggctg ccttccttga gggattttat gagataatcc ccaaacgtct catctccatc
    13081 tttactgagc aggaattgga actgcttatc tctggcctcc ccactataga tattgatgac
    13141 ctaaaatcaa acactgagta tcacaagtac cagtctaact ctatccagat tcagtggttc
    13201 tggagagcgt tgcgctcatt tgatcaggct gaccgggcaa agttccttca gtttgttact
    13261 gggacttcaa aggttccact acagggtttt gctgcgctag aaggaatgaa tggcatccaa
    13321 aaattccaaa ttcacagaga tgacagatct acagacaggc tgccttctgc acacacatgc
    13381 ttcaaccagt tggaccttcc agcttatgag agttacgaga agctacgtca catgctgctg
    13441 ttagccattc aggagtgctc tgagggcttt ggccttgcct agagatggcc tgctgttttc
    13501 tactgttgga ctgatctggg agaaaaagca aaacaaagcc atgcatctgt ctcgctcacc
    13561 ctactggctt ctacaagagg gacttgcctt ctaaagctgc cgtctgtctc cgttcccttc
    13621 cgacggcgaa ctggttgtgc cgagacttga caacactgat ctgagggatg taggcaatgg
    13681 gaggagcagg ggggaaatta tatataagta tataaatata tttttttctg ttttgctttt
    13741 cttcattttt gcttatgggt gagttacgat gcgctgactt tacccatgaa agctcaaagt
    13801 gcaggaggga gagaatcaaa tgttgaagaa acttgtgtca gaaagcagag attcattgga
    13861 gaactgaaac aacagagcac tctttatgaa acagccacta ttcccaacgc atttttgttt
    13921 ttccagtttc aaatacagtt ctgaggtgtt tacctgtaaa taaaccactg aaccgaaaat
    13981 acccaatcaa tacagttttt cttttttttt cttttttttt ttgccctgtt tggcagtttg
    14041 gctgtgatgg taaaatgcac cgggagggtt aaagctacag ttgggcaata caagtggtat
    14101 atgcagaata cctaatgact tgcagaaatt actttgcagt tgtgttttcc catgtcttat
    14161 cagagaggtt gcattgtttg ggtgttcatt ttttatgcaa atgggaaata tatgtgcatt
    14221 gaaatgtaaa gcaaaatgta caaaaaatca ctttagccaa gttttttctt gttttttgtt
    14281 tttttacccc cctcccccca atccttatat ttatttagac ccccttaaac attttccccc
    14341 ccttctaaat gatttcaggt ttgaattgct aggattttct gttttggaag tttttggaat
    14401 ttctcttaaa aactgaaata aaaaagaaaa agctaa
//
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