Mus musculus voltage-gated sodium channel alpha subunit SCN8A (Scn8a) - Nucleotide

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Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy. [JCI Insight. 2024]
Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy.
Miralles RM, Boscia AR, Kittur S, Hanflink JC, Panchal PS, Yorek MS, Deutsch TCJ, Reever CM, Vundela SR, Wengert ER, et al. JCI Insight. 2024 Oct 22; 9(20). Epub 2024 Oct 22.
Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy. [Neurobiol Dis. 2024]
Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy.
Yu W, Hill SF, Zhu L, Demetriou Y, Reger F, Mattis J, Meisler MH. Neurobiol Dis. 2024 Sep; 199:106591. Epub 2024 Jul 3.
Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6. [Sci Rep. 2024]
Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6.
Arratia LM, Bermudes-Contreras JD, Juarez-Monroy JA, Romero-Macías EA, Luna-Rojas JC, López-Hidalgo M, Vega AV, Zamorano-Carrillo A. Sci Rep. 2024 Mar 21; 14(1):6761. Epub 2024 Mar 21.

RefSeq alternative splicing
See 12 reference mRNA sequence splice variants for the Scn8a gene.

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Nucleotide