LOCUS NM_206683 5296 bp mRNA linear INV 26-DEC-2023
DEFINITION Drosophila melanogaster discs large 1 (dlg1), transcript variant B,
mRNA.
ACCESSION NM_206683
VERSION NM_206683.4
DBLINK BioProject: PRJNA164
BioSample: SAMN02803731
KEYWORDS RefSeq.
SOURCE Drosophila melanogaster (fruit fly)
ORGANISM Drosophila melanogaster
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE 1 (bases 1 to 5296)
AUTHORS Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
Strelets,V., Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: Impact of
High-Throughput Data
JOURNAL G3 (Bethesda) 5 (8), 1721-1736 (2015)
PUBMED 26109357
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 5296)
AUTHORS Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
Russo,S.M. and Gelbart,W.M.
CONSRTM FlyBase Consortium
TITLE Gene Model Annotations for Drosophila melanogaster: The
Rule-Benders
JOURNAL G3 (Bethesda) 5 (8), 1737-1749 (2015)
PUBMED 26109356
REMARK Publication Status: Online-Only
REFERENCE 3 (bases 1 to 5296)
AUTHORS Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
TITLE The Release 6 reference sequence of the Drosophila melanogaster
genome
JOURNAL Genome Res 25 (3), 445-458 (2015)
PUBMED 25589440
REFERENCE 4 (bases 1 to 5296)
AUTHORS Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
TITLE Sequence finishing and mapping of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1625-1628 (2007)
PUBMED 17569867
REFERENCE 5 (bases 1 to 5296)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
TITLE The Release 5.1 annotation of Drosophila melanogaster
heterochromatin
JOURNAL Science 316 (5831), 1586-1591 (2007)
PUBMED 17569856
REMARK Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE 6 (bases 1 to 5296)
AUTHORS Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
Ashburner,M. and Anxolabehere,D.
TITLE Combined evidence annotation of transposable elements in genome
sequences
JOURNAL PLoS Comput Biol 1 (2), 166-175 (2005)
PUBMED 16110336
REFERENCE 7 (bases 1 to 5296)
AUTHORS Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
Celniker,S.E., Rubin,G.M. and Karpen,G.H.
TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly
JOURNAL Genome Biol 3 (12), RESEARCH0085 (2002)
PUBMED 12537574
REFERENCE 8 (bases 1 to 5296)
AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
Rubin,G.M., Ashburner,M. and Celniker,S.E.
TITLE The transposable elements of the Drosophila melanogaster
euchromatin: a genomics perspective
JOURNAL Genome Biol 3 (12), RESEARCH0084 (2002)
PUBMED 12537573
REFERENCE 9 (bases 1 to 5296)
AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
Rubin,G.M. and Lewis,S.E.
TITLE Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review
JOURNAL Genome Biol 3 (12), RESEARCH0083 (2002)
PUBMED 12537572
REFERENCE 10 (bases 1 to 5296)
AUTHORS Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
Gibbs,R.A. and Rubin,G.M.
TITLE Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence
JOURNAL Genome Biol 3 (12), RESEARCH0079 (2002)
PUBMED 12537568
REFERENCE 11 (bases 1 to 5296)
AUTHORS Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
TITLE The genome sequence of Drosophila melanogaster
JOURNAL Science 287 (5461), 2185-2195 (2000)
PUBMED 10731132
REFERENCE 12 (bases 1 to 5296)
AUTHORS Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
Smith,E., Yu,C. and Rubin,G.
CONSRTM Berkeley Drosophila Genome Project
TITLE Drosophila melanogaster release 4 sequence
JOURNAL Unpublished
REFERENCE 13 (bases 1 to 5296)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (20-DEC-2023) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 14 (bases 1 to 5296)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 15 (bases 1 to 5296)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 16 (bases 1 to 5296)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (20-APR-2020) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 17 (bases 1 to 5296)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (22-APR-2019) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 18 (bases 1 to 5296)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 19 (bases 1 to 5296)
CONSRTM FlyBase
TITLE Direct Submission
JOURNAL Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE 20 (bases 1 to 5296)
AUTHORS Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
Park,S., Svirskas,R. and Karpen,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 21 (bases 1 to 5296)
AUTHORS Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
Svirskas,R. and Rubin,G.
TITLE Direct Submission
JOURNAL Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
64-121, Berkeley, CA 94720, USA
REMARK Direct Submission
REFERENCE 22 (bases 1 to 5296)
AUTHORS Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
CONSRTM Drosophila Heterochromatin Genome Project
TITLE Direct Submission
JOURNAL Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE 23 (bases 1 to 5296)
AUTHORS Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
TITLE Direct Submission
JOURNAL Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
Rockville, MD 20850, USA
COMMENT REVIEWED REFSEQ: This record has been curated by FlyBase. This
record is derived from an annotated genomic sequence (NC_004354).
On Jan 16, 2013 this sequence version replaced NM_206683.3.
##Genome-Annotation-Data-START##
Annotation Provider :: FlyBase
Annotation Status :: Full annotation
Annotation Version :: Release 6.54
URL :: http://flybase.org
##Genome-Annotation-Data-END##
FEATURES Location/Qualifiers
source 1..5296
/organism="Drosophila melanogaster"
/mol_type="mRNA"
/db_xref="taxon:7227"
/chromosome="X"
/genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
gene 1..5296
/gene="dlg1"
/locus_tag="Dmel_CG1725"
/gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258;
anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730;
CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG;
dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA;
dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn;
l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg;
l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456;
l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95;
PSD95; SAP97"
/note="discs large 1"
/map="10B6-10B10"
/db_xref="FLYBASE:FBgn0001624"
/db_xref="GeneID:32083"
CDS 811..3723
/gene="dlg1"
/locus_tag="Dmel_CG1725"
/gene_synonym="11; anon-EST:Posey93; anon-WO03040301.258;
anon-WO03040301.260; anon-WO03040301.268; CG1725; CG1730;
CPD; d. lg.-1; Discs Large; Discs-large; dlg; Dlg; DLG;
dlg-1; dlg-A; Dlg-A; DLG-A; Dlg1; DLG1; dlgA; DlgA;
dlgS97; DlgS97; Dmel\CG1725; Drodlg; l(1)10Bf; l(1)bwn;
l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg;
l(1)dlg-1; l(1)dlg1; l(1)G0276; l(1)G0342; l(1)G0456;
l(1)G19; l(1)l.pr.-2; l(1)L11; l(1)lpr-2; misb; PSD-95;
PSD95; SAP97"
/EC_number="2.7.4.8"
/note="CG1725 gene product from transcript CG1725-RB;
CG1725-PB; dlg1-PB; discslarge; disc large;
lethal(1)discs-large; lethal(2)discs large; disk large;
Disc-Large; disclarge; Discs-large; discs large 1;
lethal(1)benign wing imaginal disc neoplasm; Discs-large
1; lethal(1)discs large"
/codon_start=1
/product="discs large 1, isoform B"
/protein_id="NP_996406.1"
/db_xref="FLYBASE:FBpp0089351"
/db_xref="GeneID:32083"
/db_xref="FLYBASE:FBgn0001624"
/translation="MPVKKQEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSR
LFQALLDIQEFYELTLLDDSKSIQQKTAETLQIATKWEKDGQAVKIADFIKSSNLNRN
CAYEFNNDASSNQTNQSALNQNPIANNVSAQAQAEALSRTFKSELEEILNQRMRIESD
TENAKEPTVEQQQKQQQAQQRSSRSPQQQNPQQQQGSKSRSGSQTVNGDDSWLYEDIQ
LERGNSGLGFSIAGGTDNPHIGTDTSIYITKLISGGAAAADGRLSINDIIVSVNDVSV
VDVPHASAVDALKKAGNVVKLHVKRKRGTATTPAAGSAAGDARDSAASGPKVIEIDLV
KGGKGLGFSIAGGIGNQHIPGDNGIYVTKLMDGGAAQVDGRLSIGDKLIAVRTNGSEK
NLENVTHELAVATLKSITDKVTLIIGKTQHLTTSASGGGGGGLSSGQQLSQSQSQLAT
SQSQSQVHQQQHATPMVNSQSTEPGSRYASTNVLAAVPPGTPRAVSTEDITREPRTIT
IQKGPQGLGFNIVGGEDGQGIYVSFILAGGPADLGSELKRGDQLLSVNNVNLTHATHE
EAAQALKTSGGVVTLLAQYRPEEYNRFEARIQELKQQAALGAGGSGTLLRTTQKRSLY
VRALFDYDPNRDDGLPSRGLPFKHGDILHVTNASDDEWWQARRVLGDNEDEQIGIVPS
KRRWERKMRARDRSVKFQGHAAANNNLDKQSTLDRKKKNFTFSRKFPFMKSRDEKNED
GSDQEPFMLCYTQDDANAEGASEENVLSYEAVQRLSINYTRPVIILGPLKDRINDDLI
SEYPDKFGSCVPHTTRPKREYEVDGRDYHFVSSREQMERDIQNHLFIEAGQYNDNLYG
TSVASVREVAEKGKHCILDVSGNAIKRLQVAQLYPVAVFIKPKSVDSVMEMNRRMTEE
QAKKTYERAIKMEQEFGEYFTGVVQGDTIEEIYSKVKSMIWSQSGPTIWVPSKESL"
ORIGIN
1 gatcccaact agaactagtg ttcccgtgag cagagcagaa aaccgtaata tatattctcc
61 aacgtgctgc cgctacttat ttatattaaa cataaaatgc ccgaaggctg tgccaaacgc
121 atgtcctttt tgccaatggt gaatgcaata tagaatcaaa tcaagtgaac gcgaagtaag
181 caaataaacg atctgagttt ttttttgtgt tggtgttgtt gtgttgtgac gaggaaagta
241 cgacatttcg atgatagtcg cattgcaata taaagtgcaa cataaatgct atagaaccga
301 atgtgaatgt gaggagccat tgagctgtga aatgtgaaaa tcgcaaagaa atcgagagaa
361 aacgcacacg tcaatgtaac cacaaagctg ccccaagaaa acgaaaagta aaatatataa
421 agaaattaaa aaataaacta gcaaactgaa agcgcaaaat taaaaaaaaa acaacaaatc
481 tcgaactttg ttcgaaagcc aaagtatcta acaaaacaat atttgtacat aaaacaccat
541 cgaatagtat atatatatat atacatatat atcagatata tatacagatg tgctggcgaa
601 actaaaagga ggagaactca aggaaaagcc aaagcgattt ttccgcacat ttccactcga
661 aagcgactcc agtaaattct caaaattgcg acccacgctt ttcccagttc ggcggcgttg
721 aaccacaatc aaagctgctg caccaccgcc atttccgctg ccatttccac cagcaccacc
781 ataaatagta gcagaaacac cgctcacaga atgccagtga aaaagcaaga agctcatcgg
841 gctctcgagc tgctcgagga ctaccacgcg agactttcgg agccgcagga tcgggcgctg
901 cgtattgcaa tcgaacgcgt tatacgcata tttaaatctc gcttgtttca agcgctgtta
961 gatatacaag aattctatga attgacatta ttggatgact cgaagagcat acaacaaaag
1021 acagcggaga ccttgcaaat tgcaaccaaa tgggaaaagg atggccaggc agtcaaaata
1081 gctgatttta tcaaatcttc aaacctcaat cgcaattgcg cctatgagtt taacaacgac
1141 gcctcatcca atcaaaccaa ccaatcagca ctcaatcaga atccgatcgc gaataatgtg
1201 agtgcccaag cgcaggccga ggccctcagc agaacattta agagtgaatt ggaagagatc
1261 ttgaatcagc gcatgcgcat cgaatcggac acggaaaatg ccaaggagcc aactgtcgag
1321 cagcagcaaa agcagcagca agcgcagcag cgcagttccc gctccccgca gcagcagaat
1381 ccgcagcagc agcagggatc caaatcgagg agcgggtccc agactgtgaa tggcgatgat
1441 agctggttat acgaggacat tcagctggag cgcggcaact ccggattggg cttttccatt
1501 gccggcggta cggataatcc gcacatcggc accgacacct ccatctacat caccaagctc
1561 atttccggtg gagcagctgc cgccgatgga cgtctgagca tcaacgatat catcgtatcg
1621 gtgaacgatg tgtccgtggt ggatgtgcca catgcctccg ccgtggatgc cctcaagaag
1681 gcgggcaatg ttgttaagct gcatgtgaag cgaaaacgtg gaacggccac caccccggca
1741 gcgggatcgg cggcaggaga tgctcgggat agtgcggcca gcggaccgaa ggtcatcgaa
1801 atcgatctgg tcaagggcgg caagggactg ggcttctcaa ttgccggcgg cattggcaac
1861 cagcacatcc ccggcgacaa tggcatctat gtgaccaagt tgatggacgg cggagcagcg
1921 caggtggacg gacgtctctc catcggagat aagctgattg cagtgcgcac caacgggagc
1981 gagaagaacc tggagaacgt aacgcacgaa ctggcggtgg ccacgttgaa atcgatcacc
2041 gacaaggtga cgctgatcat tggaaagaca cagcatctga ccaccagtgc gtccggcggc
2101 ggaggaggag gcctttcatc cggacaacaa ttgtcgcagt cccaatcgca gttggccacc
2161 agccagagcc aaagtcaggt gcatcagcag cagcatgcga cgccgatggt caattcgcag
2221 tcgacagagc ccgggtcgcg atacgcctct acaaatgtcc tagccgccgt tccaccagga
2281 actccacgcg ctgtcagcac cgaggatata accagagaac cgcgcaccat caccatccag
2341 aagggaccgc agggcctggg cttcaatatc gttggcggcg aggatggcca gggtatctat
2401 gtgtccttca tcctggccgg cggcccagcg gatctcgggt cggagttgaa gcgtggcgac
2461 cagctgctca gcgtgaacaa tgtcaatctc acgcacgcca cccacgaaga ggcagcccag
2521 gcgctcaaga cttctggcgg tgtggtgacc ctgttggcgc agtaccgccc agaggagtac
2581 aatcgcttcg aggcacgcat tcaagagttg aaacaacagg ctgccctcgg tgccggcgga
2641 tcgggaacgc tgctgcgcac cacgcaaaag cgatcgctgt atgtgcgcgc cctgtttgac
2701 tacgatccga atcgggatga tggattgccc tcgcgaggat tgccctttaa gcacggcgat
2761 atcctgcacg tgaccaatgc ctccgacgat gaatggtggc aggcacgacg agttctcggc
2821 gacaacgagg acgagcaaat cggtattgta ccatcgaaaa ggcgttggga gcgcaaaatg
2881 cgagctaggg accgcagcgt taagttccag ggacatgcgg cagctaataa taatctggat
2941 aagcaatcga cattggatcg aaagaaaaag aatttcacat tctcgcgcaa atttccgttt
3001 atgaagagtc gcgatgagaa gaatgaagat ggcagcgacc aagagccctt tatgctttgc
3061 tacacacaag acgatgccaa tgctgaagga gcttccgagg agaacgtgtt gtcctacgag
3121 gccgtacagc gtttgtccat caactacacg cgcccggtga ttattctggg acccctgaag
3181 gatcgcatca acgatgacct tatatcagag tatcccgaca agttcggctc ttgtgtgcca
3241 cacaccaccc gacccaagcg agagtacgag gtggatggta gggactacca ctttgtatcc
3301 tctcgcgagc aaatggaacg ggatattcag aatcatctgt tcatcgaggc gggacagtat
3361 aacgacaatc tgtacggcac atcggtggcc agcgtgcgcg aagtggccga gaagggtaaa
3421 cactgcatcc tggacgtgtc cgggaacgcc atcaagcgac tccaagttgc ccagctgtat
3481 cccgtcgccg tgttcatcaa gcccaagtcg gtggattcag tgatggaaat gaatcgtcgc
3541 atgacggagg agcaggccaa gaagacttac gagcgggcga ttaaaatgga gcaagaattc
3601 ggcgaatact ttacgggcgt tgtccaaggc gataccatcg aggagattta cagcaaagtg
3661 aaatcgatga tttggtccca gtcgggacca accatttggg taccttccaa ggaatctcta
3721 tgaccaacag ccaccacaac ttggacactg ccgcctcgag ttcgatgtcg accagtctcg
3781 agaacaacaa taggagcaac agcagcagca acaaatcagc agccgcagca gaagacgccg
3841 cactgatgat gcatcacagt aacaacagat actaatacaa ctacaacaac aacaagaaca
3901 acaacaacaa cagcaaccac agcagcagcc acagcgacaa caacaaaaac aacaacactg
3961 acaacgacag gaaacggaaa tgaaaacgga tacggaaacg taaccacaga cctgaactaa
4021 ccaatttgac cgcagacaga acaaatttat tacgacgcag ccgcagcagc caacttaatg
4081 tagcaaattg tccaaagcaa tttttttttg gatgcactca ttgatgtacg attagtagtt
4141 taggtgaacg tacatccacc agctagacgg tgacggaaat gagcgaacat cagagcaaag
4201 catttggcat taggcatatg gcatatggca tatgagatga gatatgggtg ttcaaacggt
4261 agcggacaaa ggtgtatagt ttttagttag aacaaagttg gatataaaca aaagaagcga
4321 aatataatat aaaatatgta tatatatata tatcaatata tatatatata tatagatata
4381 tacacccact tatataggtt aagatccgat tataaaaaca tagagaagag cgaaaatgag
4441 ggctttctgg agttcgttaa gcgctagagt gttgtttgtt tatgttgatg tttatatacg
4501 agagccaaga gttatagcga gttagttatg ttgacgataa tgtgtttttt tgatatatat
4561 tgacctatat gaatatgtaa acatgcagac gcaggcacag gcaccccacc catgcacacc
4621 gatgttttgc cggtgatagt gatgttgagg cacaagtgca ttgcattgca tggtggttaa
4681 ctataagtac gacaatgttt agtagctgac tacgaataat gacgacgatg acgggacgca
4741 gatgcagatg cagatgcaga tgcggatgtg aatgcgattg cgaacggttg cggatctagc
4801 ggaaagtcag acaatgacga taacgattta cgattacgat ctaatgataa tgataaatat
4861 atattgatga atattgacgc taataacgat ggagatgatg aaaaacgttg gtgcatttgt
4921 tgttagatgt atgtaatttt tcccactcgc ctttgcctaa aagcaacaca aaattaaaac
4981 aaacaagaac gatatataaa acgtataaac actagtaact agcggaaaag ttgcatatag
5041 aaccacggaa attcattcac acaaccactt actatactat atctgtacca tttagcccat
5101 agtccgcaga agatcgtcga aacaaagtca ttttactata taaacaaaac atccgcataa
5161 taatgtaaac tacgacagaa attgattgga aaaaaggaga aattgaattt gttgtcgcgt
5221 tgatttaaac ctatataatg agtaaaatat tgtatattta acaatctata aaacaaatat
5281 agtatgtaga taatac
//