LOCUS NM_105102 2614 bp mRNA linear PLN 20-OCT-2022
DEFINITION Arabidopsis thaliana regulatory protein (NPR1) (NPR1), mRNA.
ACCESSION NM_105102
VERSION NM_105102.3
DBLINK BioProject: PRJNA116
BioSample: SAMN03081427
KEYWORDS RefSeq.
SOURCE Arabidopsis thaliana (thale cress)
ORGANISM Arabidopsis thaliana
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae;
Camelineae; Arabidopsis.
REFERENCE 1 (bases 1 to 2614)
AUTHORS Theologis,A., Ecker,J.R., Palm,C.J., Federspiel,N.A., Kaul,S.,
White,O., Alonso,J., Altafi,H., Araujo,R., Bowman,C.L.,
Brooks,S.Y., Buehler,E., Chan,A., Chao,Q., Chen,H., Cheuk,R.F.,
Chin,C.W., Chung,M.K., Conn,L., Conway,A.B., Conway,A.R.,
Creasy,T.H., Dewar,K., Dunn,P., Etgu,P., Feldblyum,T.V., Feng,J.,
Fong,B., Fujii,C.Y., Gill,J.E., Goldsmith,A.D., Haas,B.,
Hansen,N.F., Hughes,B., Huizar,L., Hunter,J.L., Jenkins,J.,
Johnson-Hopson,C., Khan,S., Khaykin,E., Kim,C.J., Koo,H.L.,
Kremenetskaia,I., Kurtz,D.B., Kwan,A., Lam,B., Langin-Hooper,S.,
Lee,A., Lee,J.M., Lenz,C.A., Li,J.H., Li,Y., Lin,X., Liu,S.X.,
Liu,Z.A., Luros,J.S., Maiti,R., Marziali,A., Militscher,J.,
Miranda,M., Nguyen,M., Nierman,W.C., Osborne,B.I., Pai,G.,
Peterson,J., Pham,P.K., Rizzo,M., Rooney,T., Rowley,D., Sakano,H.,
Salzberg,S.L., Schwartz,J.R., Shinn,P., Southwick,A.M., Sun,H.,
Tallon,L.J., Tambunga,G., Toriumi,M.J., Town,C.D., Utterback,T.,
Van Aken,S., Vaysberg,M., Vysotskaia,V.S., Walker,M., Wu,D., Yu,G.,
Fraser,C.M., Venter,J.C. and Davis,R.W.
TITLE Sequence and analysis of chromosome 1 of the plant Arabidopsis
thaliana
JOURNAL Nature 408 (6814), 816-820 (2000)
PUBMED 11130712
REFERENCE 2 (bases 1 to 2614)
CONSRTM NCBI Genome Project
TITLE Direct Submission
JOURNAL Submitted (19-OCT-2022) National Center for Biotechnology
Information, NIH, Bethesda, MD 20894, USA
REFERENCE 3 (bases 1 to 2614)
AUTHORS Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
Vaughn,M. and Town,C.D.
TITLE Direct Submission
JOURNAL Submitted (18-JUL-2017) Plant Genomics, J. Craig Venter Institute,
9704 Medical Center Dr, Rockville, MD 20850, USA
REMARK Protein update by submitter
REFERENCE 4 (bases 1 to 2614)
AUTHORS Krishnakumar,V., Cheng,C.-Y., Chan,A.P., Schobel,S., Kim,M.,
Ferlanti,E.S., Belyaeva,I., Rosen,B.D., Micklem,G., Miller,J.R.,
Vaughn,M. and Town,C.D.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2016) Plant Genomics, J. Craig Venter Institute,
9704 Medical Center Dr, Rockville, MD 20850, USA
REMARK Protein update by submitter
REFERENCE 5 (bases 1 to 2614)
AUTHORS Swarbreck,D., Lamesch,P., Wilks,C. and Huala,E.
CONSRTM TAIR
TITLE Direct Submission
JOURNAL Submitted (18-FEB-2011) Department of Plant Biology, Carnegie
Institution, 260 Panama Street, Stanford, CA, USA
COMMENT REVIEWED REFSEQ: This record has been curated by TAIR and Araport.
This record is derived from an annotated genomic sequence
(NC_003070).
On Sep 12, 2016 this sequence version replaced NM_105102.2.
FEATURES Location/Qualifiers
source 1..2614
/organism="Arabidopsis thaliana"
/mol_type="mRNA"
/db_xref="taxon:3702"
/chromosome="1"
/ecotype="Columbia"
gene 1..2614
/gene="NPR1"
/locus_tag="AT1G64280"
/gene_synonym="ARABIDOPSIS NONEXPRESSER OF PR GENES 1;
ATNPR1; F15H21.6; F15H21_6; NIM1; NON-INDUCIBLE IMMUNITY
1; NONEXPRESSER OF PR GENES 1; REGULATORY PROTEIN NPR1;
SAI1; SALICYLIC ACID INSENSITIVE 1"
/note="This gene is a key regulator of the salicylic acid
(SA)-mediated systemic acquired resistance (SAR) pathway.
It is similar to the transcription factor inhibitor I
kappa B, and contains ankyrin repeats. It confers
resistance to the pathogens Pseudomonas syringae and
Peronospora parasitica in a dosage-dependent fashion.
Although transgenic Arabidopsis plants overexpressing NPR1
acquire enhanced sensitivity to SA and (benzothiadiazole)
BTH, they display no obvious detrimental morphological
changes and do not have elevated pathogenesis-related gene
expression until activated by inducers or pathogens."
/db_xref="Araport:AT1G64280"
/db_xref="GeneID:842733"
/db_xref="TAIR:AT1G64280"
CDS 252..2033
/gene="NPR1"
/locus_tag="AT1G64280"
/gene_synonym="ARABIDOPSIS NONEXPRESSER OF PR GENES 1;
ATNPR1; F15H21.6; F15H21_6; NIM1; NON-INDUCIBLE IMMUNITY
1; NONEXPRESSER OF PR GENES 1; REGULATORY PROTEIN NPR1;
SAI1; SALICYLIC ACID INSENSITIVE 1"
/inference="Similar to RNA sequence,
EST:INSD:EL201365.1,INSD:BP666956.1,INSD:BP598549.1,
INSD:BP622100.1,INSD:BP571537.1,INSD:BP577700.1,
INSD:EH838194.1,INSD:BP571734.1,INSD:EL137225.1,
INSD:AV557971.1,INSD:AV792794.1,INSD:AI997958.1,
INSD:EL235963.1,INSD:AV803934.1,INSD:AV796340.1,
INSD:AV538866.1,INSD:BU636357.1,INSD:EL154260.1,
INSD:EL154331.1,INSD:BP580253.1,INSD:DR750055.1,
INSD:EG528533.1,INSD:BP581315.1,INSD:BP856785.1,
INSD:T22612.1,INSD:AV551266.1,INSD:BP570007.1,
INSD:DR377801.1,INSD:BP566856.1,INSD:BX839797.1,
INSD:BP581392.1,INSD:DR750054.1,INSD:BP868377.1,
INSD:EL286142.1,INSD:BP797190.1,INSD:BP779221.1,
INSD:DR290816.1,INSD:AA395706.1,INSD:DR290817.1,
INSD:BP644819.1,INSD:EG528500.1,INSD:EL054377.1,
INSD:BP824743.1,INSD:BP669451.1,INSD:AV825882.1,
INSD:BP666819.1"
/inference="similar to RNA sequence,
mRNA:INSD:AY088183.1,INSD:AY050455.1,INSD:BX817021.1,
INSD:BX813873.1,INSD:AY093992.1,INSD:BX815924.1,
INSD:U76707.1"
/note="NONEXPRESSER OF PR GENES 1 (NPR1); CONTAINS
InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), NPR1/NIM1
like, C-terminal (InterPro:IPR021094), BTB/POZ fold
(InterPro:IPR011333), Ankyrin repeat-containing domain
(InterPro:IPR020683), BTB/POZ-like (InterPro:IPR000210),
Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis
thaliana protein match is: Ankyrin repeat family protein /
BTB/POZ domain-containing protein (TAIR:AT4G26120.1); Has
5193 Blast hits to 3365 proteins in 257 species: Archae -
2; Bacteria - 309; Metazoa - 2278; Fungi - 110; Plants -
802; Viruses - 16; Other Eukaryotes - 1676 (source: NCBI
BLink)."
/codon_start=1
/product="regulatory protein (NPR1)"
/protein_id="NP_176610.1"
/db_xref="Araport:AT1G64280"
/db_xref="GeneID:842733"
/db_xref="TAIR:AT1G64280"
/translation="MDTTIDGFADSYEISSTSFVATDNTDSSIVYLAAEQVLTGPDVS
ALQLLSNSFESVFDSPDDFYSDAKLVLSDGREVSFHRCVLSARSSFFKSALAAAKKEK
DSNNTAAVKLELKEIAKDYEVGFDSVVTVLAYVYSSRVRPPPKGVSECADENCCHVAC
RPAVDFMLEVLYLAFIFKIPELITLYQRHLLDVVDKVVIEDTLVILKLANICGKACMK
LLDRCKEIIVKSNVDMVSLEKSLPEELVKEIIDRRKELGLEVPKVKKHVSNVHKALDS
DDIELVKLLLKEDHTNLDDACALHFAVAYCNVKTATDLLKLDLADVNHRNPRGYTVLH
VAAMRKEPQLILSLLEKGASASEATLEGRTALMIAKQATMAVECNNIPEQCKHSLKGR
LCVEILEQEDKREQIPRDVPPSFAVAADELKMTLLDLENRVALAQRLFPTEAQAAMEI
AEMKGTCEFIVTSLEPDRLTGTKRTSPGVKIAPFRILEEHQSRLKALSKTVELGKRFF
PRCSAVLDQIMNCEDLTQLACGEDDTAEKRLQKKQRYMEIQETLKKAFSEDNLELGNS
SLTDSTSSTSKSTGGKRSNRKLSHRRR"
ORIGIN
1 cttcctgtta tatcttttta aaaaagatct ctgacaaaga ttcctttcct ggaaatttac
61 cggttttggt gaaatgtaaa ccgtgggacg aggatgcttc ttcatatctc accaccactc
121 tcgttgactt gacttggctc tgctcgtcaa tggttatctt cgatctttaa ccaaatccag
181 ttgataaggt ctcttcgttg attagcagag atctctttaa tttgtgaatt tcaattcatc
241 ggaacctgtt gatggacacc accattgatg gattcgccga ttcttatgaa atcagcagca
301 ctagtttcgt cgctaccgat aacaccgact cctctattgt ttatctggcc gccgaacaag
361 tactcaccgg acctgatgta tctgctctgc aattgctctc caacagcttc gaatccgtct
421 ttgactcgcc ggatgatttc tacagcgacg ctaagcttgt tctctccgac ggccgggaag
481 tttctttcca ccggtgcgtt ttgtcagcga gaagctcttt cttcaagagc gctttagccg
541 ccgctaagaa ggagaaagac tccaacaaca ccgccgccgt gaagctcgag cttaaggaga
601 ttgccaagga ttacgaagtc ggtttcgatt cggttgtgac tgttttggct tatgtttaca
661 gcagcagagt gagaccgccg cctaaaggag tttctgaatg cgcagacgag aattgctgcc
721 acgtggcttg ccggccggcg gtggatttca tgttggaggt tctctatttg gctttcatct
781 tcaagatccc tgaattaatt actctctatc agaggcactt attggacgtt gtagacaaag
841 ttgttataga ggacacattg gttatactca agcttgctaa tatatgtggt aaagcttgta
901 tgaagctatt ggatagatgt aaagagatta ttgtcaagtc taatgtagat atggttagtc
961 ttgaaaagtc attgccggaa gagcttgtta aagagataat tgatagacgt aaagagcttg
1021 gtttggaggt acctaaagta aagaaacatg tctcgaatgt acataaggca cttgactcgg
1081 atgatattga gttagtcaag ttgcttttga aagaggatca caccaatcta gatgatgcgt
1141 gtgctcttca tttcgctgtt gcatattgca atgtgaagac cgcaacagat cttttaaaac
1201 ttgatcttgc cgatgtcaac cataggaatc cgaggggata tacggtgctt catgttgctg
1261 cgatgcggaa ggagccacaa ttgatactat ctctattgga aaaaggtgca agtgcatcag
1321 aagcaacttt ggaaggtaga accgcactca tgatcgcaaa acaagccact atggcggttg
1381 aatgtaataa tatcccggag caatgcaagc attctctcaa aggccgacta tgtgtagaaa
1441 tactagagca agaagacaaa cgagaacaaa ttcctagaga tgttcctccc tcttttgcag
1501 tggcggccga tgaattgaag atgacgctgc tcgatcttga aaatagagtt gcacttgctc
1561 aacgtctttt tccaacggaa gcacaagctg caatggagat cgccgaaatg aagggaacat
1621 gtgagttcat agtgactagc ctcgagcctg accgtctcac tggtacgaag agaacatcac
1681 cgggtgtaaa gatagcacct ttcagaatcc tagaagagca tcaaagtaga ctaaaagcgc
1741 tttctaaaac cgtggaactc gggaaacgat tcttcccgcg ctgttcggca gtgctcgacc
1801 agattatgaa ctgtgaggac ttgactcaac tggcttgcgg agaagacgac actgctgaga
1861 aacgactaca aaagaagcaa aggtacatgg aaatacaaga gacactaaag aaggccttta
1921 gtgaggacaa tttggaatta ggaaattcgt ccctgacaga ttcgacttct tccacatcga
1981 aatcaaccgg tggaaagagg tctaaccgta aactctctca tcgtcgtcgg tgagactctt
2041 gcctcttagt gtaatttttg ctgtaccata taattctgtt ttcatgatga ctgtaactgt
2101 ttatgtctat cgttggcgtc atatagtttc gctcttcgtt ttgcatcctg tgtattattg
2161 ctgcaggtgt gcttcaaaca aatgttgtaa caatttgaac caatggtata cagatttgta
2221 atatatattt atgtacatca acaataaccc atgatggtgt tacagagttg ctagaatcaa
2281 agtgtgaaat aatgtcaaat tgttcatctg ttggatattt tccaccaaga accaaaagaa
2341 tattcaagtt ccctgaactt ctggcaacat tcatgttata tgtatcttcc taattcttcc
2401 tttaaccttt tgtaactcga attacacagc aagttagttt caggtctaga gataagagaa
2461 cactgagtgg gcgtgtaagg tgcattctcc tagtcagctc cattgcatcc aacatttgtg
2521 aatgacacaa gttaacaatc ctttgcacca tttctgggtg catacatgga aacttcttcg
2581 attgaaactt cccacatgtg caggtgcgtt cgct
//