Homo sapiens rhomboid 5 homolog 2 (RHBDF2), transcript variant 1, mRNA

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Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals. [Mol Cell. 2024]
Cryo-EM reveals that iRhom2 restrains ADAM17 protease activity to control the release of growth factor and inflammatory signals.
Lu F, Zhao H, Dai Y, Wang Y, Lee CH, Freeman M. Mol Cell. 2024 Jun 6; 84(11):2152-2165.e5. Epub 2024 May 22.
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I. [Cell Mol Life Sci. 2024]
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I.
Calligaris M, Spanò DP, Bonelli S, Müller SA, Carcione C, D'apolito D, Amico G, Miele M, Di Bella M, Zito G, et al. Cell Mol Life Sci. 2024 Apr 4; 81(1):163. Epub 2024 Apr 4.
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway. [Mol Cell. 2024]
Cleavage of the pseudoprotease iRhom2 by the signal peptidase complex reveals an ER-to-nucleus signaling pathway.
Dulloo I, Tellier M, Levet C, Chikh A, Zhang B, Blaydon DC, Webb CM, Kelsell DP, Freeman M. Mol Cell. 2024 Jan 18; 84(2):277-292.e9. Epub 2024 Jan 5.

RefSeq alternative splicing
See 40 reference mRNA sequence splice variants for the RHBDF2 gene.
RefSeq protein product
See the reference protein sequence for inactive rhomboid protein 2 isoform 1 (NP_078875.4).

Protein
Protein sequence from Nucleotide coding region
PubMed
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Taxonomy
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Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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OMIM
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PubMed (RefSeq)
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SNP
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GEO Profiles
GEO Profile records associated with Nucleotide record

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Nucleotide