LOCUS NM_022473 10890 bp mRNA linear PRI 06-AUG-2019
DEFINITION Homo sapiens zinc finger protein 106 (ZNF106), transcript variant
1, mRNA.
ACCESSION NM_022473
VERSION NM_022473.2
KEYWORDS RefSeq; RefSeq Select.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 10890)
AUTHORS Contreras-Martos S, Piai A, Kosol S, Varadi M, Bekesi A, Lebrun P,
Volkov AN, Gevaert K, Pierattelli R, Felli IC and Tompa P.
TITLE Linking functions: an additional role for an intrinsically
disordered linker domain in the transcriptional coactivator CBP
JOURNAL Sci Rep 7 (1), 4676 (2017)
PUBMED 28680062
REMARK GeneRIF: Study identified ZFP106 as a novel substrate for
CBP-mediated acetylation, and showed that the fully disordered
isolated ID3 in CREBBP transiently interacts with an IDR of ZFP106
in a fashion that both IDR regions are maintained.
Publication Status: Online-Only
REFERENCE 2 (bases 1 to 10890)
AUTHORS Grasberger H, Ye H, Mashima H and Bell GI.
TITLE Dual promoter structure of ZFP106: regulation by myogenin and
nuclear respiratory factor-1
JOURNAL Gene 344, 143-159 (2005)
PUBMED 15656981
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
AK091929.1, AF205632.1 and AI658947.1.
[WARNING] On Apr 21, 2020 this sequence was replaced by
NM_022473.3.
On Sep 27, 2013 this sequence version replaced NM_022473.1.
##Evidence-Data-START##
Transcript exon combination :: AF205632.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support
SAMEA1965299, SAMEA1966682
[ECO:0000350]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on conservation, expression
##RefSeq-Attributes-END##
COMPLETENESS: complete on the 3' end.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-35 AK091929.1 1-35
36-10495 AF205632.1 9-10468
10496-10890 AI658947.1 1-395 c
FEATURES Location/Qualifiers
source 1..10890
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="15"
/map="15q15.1"
gene 1..10890
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/note="zinc finger protein 106"
/db_xref="GeneID:64397"
/db_xref="HGNC:HGNC:12886"
exon 1..610
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
misc_feature 294..296
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/note="upstream in-frame stop codon"
CDS 363..6014
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/note="isoform 1 is encoded by transcript variant 1;
SH3-domain binding protein 3; zinc finger protein 474"
/codon_start=1
/product="zinc finger protein 106 isoform 1"
/protein_id="NP_071918.1"
/db_xref="CCDS:CCDS32208.1"
/db_xref="GeneID:64397"
/db_xref="HGNC:HGNC:12886"
/translation="MPVGRIECPSSPSFPRDISHECRVCGVTEVGLSAYAKHISGQLH
KDNVDAQEREDDGKGEEEEEDYFDKELIQLIKQRKEQSRQDEPSNSNQEINSDDRRPQ
WRREDRIPYQDRESYSQPAWHHRGPPQRDWKWEKDGFNNTRKNSFPHSLRNGGGPRGR
SGWHKGVAGGSSTWFHNHSNSGGGWLSNSGAVDWNHNGTGRNSSWLSEGTGGFSSWHM
NNSNGNWKSSVRSTNNWNYSGPGDKFQPGRNRNSNCQMEDMTMLWNKKSNKSNKYSHD
RYNWQRQENDKLGTVATYRGPSEGFTSDKFPSEGLLDFNFEQLESQTTKQADTATSKV
SGKNGSAAREKPRRWTPYPSQKTLDLQSGLKDITGNKSEMIEKPLFDFSLITTGIQEP
QTDETRNSPTQKTQKEIHTGSLNHKASSDSAASFEVVRQCPTAEKPEQEHTPNKMPSL
KSPLLPCPATKSLSQKQDPKNISKNTKTNFFSPGEHSNPSNKPTVEDNHGPYISKLRS
SCPHVLKGNKSTFGSQKQSGDNLNDTLRKAKEVLQCHESLQNPLLSTSKSTRNYAKAS
RNVEESEKGSLKIEFQVHALEDESDGETSDTEKHGTKIGTLGSATTELLSGSTRTADE
KEEDDRILKTSRELSTSPCNPIVRQKESELQMTSAASPHPGLLLDLKTSLEDAQVDDS
IKSHVSYETEGFESASLDAELQKSDISQPSGPLLPELSKLGFPASLQRDLTRHISLKS
KTGVHLPEPNLNSARRIRNISGHRKSETEKESGLKPTLRQILNASRRNVNWEQVIQQV
TKKKQELGKGLPRFGIEMVPLVQNEQEALDLDGEPDLSSLEGFQWEGVSISSSPGLAR
KRSLSESSVIMDRAPSVYSFFSEEGTGKENEPQQMVSPSNSLRAGQSQKATMHLKQEV
TPRAASLRTGERAENVATQRRHSAQLSSDHIIPLMHLAKDLNSQERSIPPSENQNSQE
SNGEGNCLSSSASSALAISSLADAATDSSCTSGAEQNDGQSIRKKRRATGDGSSPELP
SLERKNKRRKIKGKKERSQVDQLLNISLREEELSKSLQCMDNNLLQARAALQTAYVEV
QRLLMLKQQITMEMSALRTHRIQILQGLQETYEPSEHPDQVPCSLTRERRNSRSQTSI
DAALLPTPFFPLFLEPPSSHVSPSPTGASLQITTSPTFQTHGSVPAPDSSVQIKQEPM
SPEQDENVNAVPPSSACNVSKELLEANREISDSCPVYPVITARLSLPESTESFHEPSQ
ELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLSFASET
PLEKEPHSPADQPEQQAESTLTSAETRGSKKKKKLRKKKSLRAAHVPENSDTEQDVLT
VKPVRKVKAGKLIKGGKVTTSTWEDSRTGREQESVRDEPDSDSSLEVLEIPNPQLEVV
AIDSSESGEEKPDSPSKKDIWNSTEQNPLETSRSGCDEVSSTSEIGTRYKDGIPVSVA
ETQTVISSIKGSKNSSEISSEPGDDDEPTEGSFEGHQAAVNAIQIFGNLLYTCSADKT
VRVYNLVSRKCIGVFEGHTSKVNCLLVTQTSGKNAALYTGSSDHTIRCYNVKSRECVE
QLQLEDRVLCLHSRWRILYAGLANGTVVTFNIKNNKRLEIFECHGPRAVSCLATAQEG
ARKLLVVGSYDCTISVRDARNGLLLRTLEGHSKTILCMKVVNDLVFSGSSDQSVHAHN
IHTGELVRIYKGHNHAVTVVNILGKVMVTACLDKFVRVYELQSHDRLQVYGGHKDMIM
CMTIHKSMIYTGCYDGSIQAVRLNLMQNYRCWWHGCSLIFGVVDHLKQHLLTDHTNPN
FQTLKCRWKNCDAFFTARKGSKQDAAGHIERHAEDDSKIDS"
misc_feature 1626..1628
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 2130..2132
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:19690332};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 2283..2285
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 2343..2345
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 2937..2939
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 2943..2945
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:19690332, ECO:0000244|PubMed:20068231,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 2952..2954
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 3039..3041
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:20068231,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 3171..3173
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 3423..3425
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 3435..3437
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:19690332, ECO:0000244|PubMed:20068231,
ECO:0000244|PubMed:21406692, ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 3438..3440
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:19690332, ECO:0000244|PubMed:20068231,
ECO:0000244|PubMed:21406692, ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 3453..3455
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:21406692}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 4107..4109
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 4197..4199
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:20068231, ECO:0000244|PubMed:21406692,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 4203..4205
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000250|UniProtKB:O88466};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 4212..4214
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:21406692};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 4266..4268
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:21406692,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 4344..4346
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:18669648,
ECO:0000244|PubMed:20068231, ECO:0000244|PubMed:21406692,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 4470..4472
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:19690332,
ECO:0000244|PubMed:20068231, ECO:0000244|PubMed:21406692,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 4476..4478
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphothreonine. {ECO:0000244|PubMed:19690332,
ECO:0000244|PubMed:23186163}; propagated from
UniProtKB/Swiss-Prot (Q9H2Y7.1); phosphorylation site"
misc_feature 4764..4766
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="Phosphoserine. {ECO:0000244|PubMed:23186163};
propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
phosphorylation site"
misc_feature 4947..5066
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
Region: WD 1"
misc_feature 5070..5195
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
Region: WD 2"
misc_feature 5322..5447
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
Region: WD 3"
misc_feature 5454..5573
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
Region: WD 4"
misc_feature 5574..5687
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
Region: WD 5"
misc_feature 5694..5807
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/experiment="experimental evidence, no additional details
recorded"
/note="propagated from UniProtKB/Swiss-Prot (Q9H2Y7.1);
Region: WD 6"
exon 611..2794
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 2795..3428
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 3429..3498
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 3499..3653
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 3654..3714
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 3715..4056
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 4057..4837
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 4838..4893
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 4894..5039
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5040..5174
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5175..5291
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5292..5483
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5484..5546
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5547..5666
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5667..5738
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5739..5810
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5811..5957
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
exon 5958..10881
/gene="ZNF106"
/gene_synonym="SH3BP3; ZFP106; ZNF474"
/inference="alignment:Splign:2.1.0"
ORIGIN
1 aaagattaaa tgtaagcgct gtcaccaggc cttctgagtg cagctggcac catgggtgtg
61 ctccagagca acttctgctt gctctgagcc ccctgccctg cctccccttt caccatgttt
121 cctctgacaa gattttaagt acagcaattc aagaagattt ctcctcctaa acgacattta
181 tctgaagtct attgcctctt gattgctgga aaagaatctt aaaatcattt caaaagtaac
241 ttataaacaa acttattaaa agtgatgaaa ggagcattga aattaattag cactaatttt
301 tcactgtgcc aaagtgtgca gtgtccttca gaggaaacaa taacagatct ggtgagtgtg
361 ccatgccagt ggggagaatt gaatgtccct catctccctc tttccctagg gacattagtc
421 atgagtgccg agtgtgcggg gtcacagaag tgggtctttc tgcatatgca aagcacattt
481 ctggccagtt gcacaaagat aacgttgatg cccaggaaag agaagatgat ggaaaaggag
541 aggaagagga agaagattat tttgacaagg aactcattca gttaataaaa caaaggaaag
601 aacaaagtcg acaagatgaa ccttccaata gcaaccaaga aataaactct gatgacagac
661 gaccccaatg gagacgagaa gaccgaattc cttaccaaga cagagagagt tacagtcagc
721 ctgcatggca tcatcgtgga cctccacagc gggattggaa atgggaaaaa gatggcttta
781 ataatactag gaaaaacagc tttccacatt ctttgaggaa tggtggtgga ccaagaggac
841 gttccgggtg gcataagggt gttgcaggag gctcctcgac ttggtttcac aaccatagta
901 attctggagg tggttggctt tcaaatagtg gagcagtaga ttggaatcat aatggtacag
961 gaaggaattc cagttggctt tctgaaggaa caggtggctt ttccagttgg catatgaaca
1021 acagtaacgg aaactggaaa tccagtgtac gtagtacaaa taattggaat tacagtggcc
1081 ctggagacaa atttcaacca ggcagaaaca gaaattctaa ctgtcaaatg gaagacatga
1141 ctatgctatg gaacaagaaa tctaataagt caaacaaata cagtcacgac agatataatt
1201 ggcagcggca agaaaatgac aaacttggta cagttgccac atatagaggt ccttctgaag
1261 gatttacaag tgataaattt ccttcagaag gcttactcga cttcaatttt gagcagctgg
1321 aaagccaaac cactaaacaa gcagacactg ctacttccaa agttagtgga aagaatggca
1381 gtgcggcaag ggaaaagcct cgtcgctgga cgccttaccc ttctcagaag actctggatt
1441 tacagtcggg attgaaagac atcactggta acaagtcaga aatgatagag aaacctctct
1501 ttgattttag cttgataact acaggaatac aggagcccca aactgatgaa acacgtaatt
1561 ccccaacaca gaaaacacaa aaagaaatac atactggatc tcttaatcac aaggcctctt
1621 ctgattccgc tgcttccttc gaggtggtga gacagtgccc cactgcagaa aaacctgaac
1681 aagagcatac accaaataaa atgccatcat tgaaatcccc actccttcca tgtccagcca
1741 ctaaatcatt gtctcaaaag caagatccaa agaatatctc aaaaaacacc aaaacaaatt
1801 ttttttcccc tggagaacac tcaaatccct cgaacaagcc cactgtggaa gataaccatg
1861 gtccttacat atccaaactg cgtagttcat gtcctcatgt tttaaaaggg aataaaagta
1921 catttggctc tcaaaagcaa tctggtgata atttaaatga tactttacga aaggccaaag
1981 aggtgctaca gtgtcatgag tcattgcaaa atccacttct tagcacttct aaaagtacca
2041 ggaactatgc aaaagcaagt agaaatgtag aagaatctga aaaagggtct ttgaaaattg
2101 agtttcaagt gcacgcacta gaagatgaaa gtgatggaga gacatctgac acggaaaagc
2161 atggaacaaa aattggaacc ctaggttctg caactacaga attgttatct ggcagcactc
2221 gaactgctga tgagaaagag gaggatgacc gcatcctgaa gacttctaga gagctatcca
2281 cttccccatg taatcccata gttcgccaga aagaatctga attacaaatg acatctgcag
2341 ccagtccaca ccctggctta ttgctagact tgaaaacctc tctagaagat gcacaggttg
2401 atgactctat taaatctcat gtatcttatg aaacagaagg ctttgagagt gctagcttgg
2461 atgcagagct tcaaaaaagt gacatcagtc agccctcggg ccctctcctg cctgaactaa
2521 gtaagcttgg ctttcctgcc tcacttcaga gggatctaac ccggcacatt agtttgaaga
2581 gcaaaactgg agtacacctt cctgagccaa acctcaatag tgcccgccgc attcgcaata
2641 ttagcggtca ccgaaagagt gagacagaga aggagtctgg gctcaagcca accctacggc
2701 agattctaaa tgcatctcgg agaaatgtca actgggaaca ggtcattcag caagtaacca
2761 agaaaaagca agagctgggc aaaggcttac ccaggtttgg catagaaatg gtaccccttg
2821 ttcaaaatga acaagaagcc ttagatttgg atggggaacc tgatctgtcc agtctagaag
2881 gattccagtg ggaaggtgtt tccatttcct cgtcccctgg cttggcaaga aagcgaagcc
2941 tttctgagag cagcgtgatc atggacagag ctccttctgt gtatagcttc ttcagtgagg
3001 aaggtacagg caaagaaaat gagccccagc agatggtttc acctagtaac tcattgaggg
3061 ctggacagag ccagaaagca accatgcacc tcaaacaaga agtgacacct cgggctgcct
3121 ccctccgaac aggtgaaagg gctgaaaatg ttgctaccca aaggcgacat agtgcacaat
3181 tatcctctga ccatataata cctttgatgc atttggcaaa agacttgaac agccaggaga
3241 ggtctatacc accgtcagag aatcagaatt cccaggagag taatggagag ggaaactgtc
3301 tgtcatcaag cgcatcctca gcccttgcga tctccagttt agcggatgca gccacagata
3361 gtagctgtac ctctggtgct gaacaaaatg atggccaaag tattagaaag aaacgaagag
3421 ccactggaga tggatcttct cctgaactcc caagtcttga gagaaaaaat aaaagaagga
3481 aaattaaagg aaaaaaagaa cgttctcagg ttgaccagct gctgaatatt tctttaaggg
3541 aggaagaact tagtaagtca ttgcagtgca tggataacaa tcttctgcaa gcccgtgcag
3601 cccttcagac agcttatgtg gaagttcaga ggctacttat gctcaagcag cagataacta
3661 tggagatgag tgcactgagg acccatagaa tacagattct acagggatta caagaaacat
3721 atgaaccttc tgagcaccca gaccaggttc cctgtagcct cacacgagaa cgaaggaaca
3781 gtagatctca aacatccatt gatgccgcac tgctgcccac tccctttttc ccactttttc
3841 tggagcctcc atcttcccat gtgtctccat cacccaccgg agcctctctt caaataacca
3901 cgtctcctac tttccaaacc catggcagtg tccctgctcc agactcatca gttcagatta
3961 aacaagagcc catgtctcct gaacaagatg agaatgtgaa tgctgtgcca ccaagctctg
4021 cctgcaatgt gtccaaggaa ttactggaag ctaatagaga gatcagtgac agttgtccag
4081 tttatccagt catcactgct agattgtcct taccagagtc aacagaaagt ttccatgagc
4141 ctagccaaga actgaagttt tctgtggagc aaagaaatac cagaaacaga gaaaactctc
4201 cctcttccca atcagctggt ctttctagca taaataaaga aggggaagag ccaaccaaag
4261 gcaatagtgg gtctgaagcc tgtaccagtt cttttctaag attgtctttt gcttcagaaa
4321 cccctttgga gaaggaaccc cactctccag ctgaccagcc tgaacaacag gcagaatcca
4381 ctttgacatc agctgagact aggggaagca agaaaaagaa gaaactccgg aagaagaaaa
4441 gtctacgggc tgcccatgtt cctgagaata gtgacactga acaggatgtt ttgactgtta
4501 aacctgtaag gaaagtaaaa gctggaaagt taattaaagg ggggaaagta acaacctcca
4561 cttgggaaga cagcaggact ggtcgggagc aggagagtgt cagagatgag ccagatagtg
4621 actcgtctct ggaagtccta gaaattccta atcctcagtt agaagtagta gccattgatt
4681 cttcagaatc aggagaagag aaaccagaca gcccatctaa aaaggatatt tggaactcta
4741 cagagcaaaa cccactagaa acgtctcgtt ctgggtgtga tgaagttagc tctaccagtg
4801 aaattggcac tcgctataaa gatggcatcc ctgtaagtgt ggcagaaact cagactgtga
4861 tctcctccat aaaaggatca aagaattctt cagaaatatc ttcagagcca ggagatgatg
4921 atgaacccac agaaggaagc tttgagggac accaagctgc cgtaaatgca attcagatat
4981 ttgggaactt gctatatacc tgttcagcag ataaaactgt tcgggtttat aatctggtga
5041 gtcggaaatg tattggtgtc tttgagggtc atacctccaa agttaactgc ctcctggtta
5101 ctcagacctc cgggaagaat gctgcccttt acaccgggtc cagtgaccat accatccgct
5161 gctataatgt taagagccga gagtgtgtgg agcagttaca gctggaagac cgggtcctct
5221 gcctccacag tagatggcga atcctctatg cgggactggc aaatggcact gtggtcacct
5281 tcaacataaa gaacaacaaa cgacttgaga tctttgaatg ccatggccct cgggcagtca
5341 gctgtcttgc tacagctcag gaaggtgccc gaaaactgct ggtcgtgggg tcttatgact
5401 gcacaattag tgtacgcgat gcccggaatg gactgctcct cagaactctg gagggccata
5461 gcaaaaccat tctttgcatg aaggtggtga atgatctcgt gttcagtggc tccagtgatc
5521 agtcagtcca tgctcacaac attcacactg gtgagctcgt gcggatctat aaaggtcaca
5581 atcatgcagt gactgtggtg aatatcctag gaaaagtgat ggtgactgct tgcctggata
5641 aatttgttcg tgtctatgaa ttacagtctc atgatcgatt acaagtttat ggaggacaca
5701 aagacatgat tatgtgtatg accatccata aaagcatgat ttacactggc tgttatgatg
5761 gcagtattca ggccgtgagg cttaatctga tgcagaatta ccgctgttgg tggcatggtt
5821 gctctctgat atttggcgtt gtagatcatt taaaacaaca cttgctgacc gaccacacta
5881 atcccaactt ccagactctg aaatgtcgct ggaagaactg cgatgctttt ttcactgcta
5941 ggaaaggatc caaacaggat gctgcaggac atattgaacg acatgctgaa gatgacagca
6001 aaattgattc atgaagtttt ttgcctccca cgttgggaag tcattagttg aactattttc
6061 acattggccc cccacacagg ccactctctt ccctttcttg gtgaagtaag gaaggagaaa
6121 gtggttacta gccaggcata cccctagcat aagtctgggc agctctatgg gatgataaat
6181 tacactttta agttcttgct ggaggtttta aatagattta gacaaatgtt aaggaaccat
6241 acttctctgg gacagcatgg catatagtga tatatgctat ttgcgttctc cagatgttta
6301 ttgaagatac agatcctaat tggttaccca gtttgaccct aatcatatgt atattttatt
6361 gatttcagtt tgcaattttt aatttatgtt cttatgatgg tttaaaccta tagtcaggct
6421 tttaagtaca agtttgttta agtgccagac tttgaggatc agttttaatt tctccatttg
6481 taatagctgg gtatttaaac tggaagcaaa tagttttctt tcttaacaat tatgtgcagt
6541 gtgtgtcact gttttcttgc tttatagata gagctggctt taagtgctaa aggacacagt
6601 agatttttga caaacagtgg ctgctctgct gactatcttt taggaattca ggaagcaaat
6661 cacatagtga caagtcctta cagacaccac ttctagtaaa tctctgtaaa tgtggataga
6721 aagctcagtg tgaggcagtg cgtagaccta acgtctacct ttacatctgc tgttgaacct
6781 gggcactacc tgttacagat cctgtcaggc tgttgaactg gaggtgtacc tttatcttcc
6841 tttctagtgt ctgaccctgc aagcctaatg ttggtttgaa cccttttggt ttgttcagtt
6901 gccagcctcc atctctccca ctgtatggcc gtgcctagac cgatggcagc catcgaatat
6961 tcctctgggc tcacggggtg ttttccaccc ccctgcagca actaagatgg tgggggagag
7021 ggggttagaa taaagcatct gaatacagtt ttcaggacct caagcagact tcctagagac
7081 ttgtttctga gacagttctt tgccttcact tccctgctag ctgggaaaga agagtggagc
7141 agagactctg cctggccact gagaacagcc aaattcacaa accctcagtg gggctttgtt
7201 tttggatttt ctccggactc atcagtaaac ctgtagaagt gtcgctttcc agccttttgt
7261 ttctggatcc tcaaaactca gaacgtggcc gggcgtggtg gctcacgcct gtaatcccag
7321 cactttggga ggctgaggca ggcagatcac ctgaggctag gagttgcaga ccagcctggc
7381 caacatggca aaaccccgtc tctactaaaa atacaaaaag ccgggcgtgg tgggcgcctg
7441 taatcccagc tgctcaggag gctgaggcag gagaatcgct tgaacccggg aggcagagat
7501 tgcagtaagc tgagatcgtg ccactgcact ccagcctggt gacagagtga gactccgtct
7561 caaaaaaaaa aaaaaaaact cagcttcttc agagagataa aattggggga ggagcccagg
7621 gccacatacc aagctttggg acatggtgcc tcatgctctc tgggattgca gaccatccag
7681 gtctgtcttc gcccctgtta gtgcacatat atccactcac atgtcttccc tcaggctatc
7741 gggcaggggg acttcaccag ggggtttatg gataggcttc aagagggtct gtgagccccc
7801 agaaattgtg tgtgagactg agtatgtgtt cttttttcca ggaaaggctc cagtggttct
7861 tacttgatcc aaaaaatgtc aagaattaat ctaggaggcc gggcctggtg gctcacacct
7921 gtaatcccag ctctttggga ggccgaggcg ggtggatcac tcaaggtcag gcatttgaga
7981 ccagcctggc caacatagtg aaaccccgtc tctattaaaa atacaaaaat tagctgggtg
8041 tggtggtatg tgcctgtagt ctcagctact caggaggctg agacaggaga atcacttgaa
8101 ccctggaggt agaagttgca gtgagccaag atcatactac tgcactccag cctgggcgac
8161 aagagtgaaa ctccacctca aaaaaaaaaa aaaaagagtt aatctaggag ataatgaatg
8221 gcctagtact agataatata tggccccaca agctcttgac ttctgtcctt ggggaaagcc
8281 attttgttaa ccacactagt gagatttaca tgatgcttaa tggagaacag agaagatctt
8341 gttgcaaaag gtgtattaaa tatttgtgct gtttctgtat gagattgaga agcttttccc
8401 acctctcacc cctatttcct ataaggatat ccagagaagc caaactgttc tgtgggtttg
8461 ggaatggtca tttcccggga aaatgcatct ggatcgatga ctaaacctgg cccttttctc
8521 tgggctgtag tgaagccgca ttttcacgct ggctggcagt gtgctgagag cctcgaatgc
8581 tctgcggcgt agtgcccttc tgccctgcct gacgatgtat cgaaaagatg agagtgaagg
8641 agactttgtg cagcaggaaa cgggtaggtg aggtgttggg cagttgtggg aacttctgag
8701 agtattacag agtggtagaa tcggtaagaa ctctgatttg gacttcgctt tggtggaact
8761 gtgtgcctat acctgcctgt gtgtgtgcaa gtgtgcaggt tcctttgtat gtatgtgtac
8821 gtgtgggaac ctgtgtttgt catatttttc ttcatttcac aaaggctttt tttgaagcag
8881 tggcagtatg cctttgtttc aagaacacat gaaattcttt taacaccaga ttagtgtgtt
8941 accccaaatg aacggttcta gccctctatt aagaaataaa gggaccataa gcattttggc
9001 tgcttatggc tgtgtgttac tacttacaag agtcttgaaa attatacaga actttgcctt
9061 ctttttttaa tgtcttccac aatgttgtga ctgattataa ccctgtttcc cctcagagaa
9121 gagctatggc tcagggatct gtgttgactc tggcatttag tggctttgtg aaggaaagaa
9181 accattaaat gacctgacaa aaactgactc atgtctttaa agtagttgaa gccactttta
9241 gaatgttact ctcggttgct tttgtctaat tctaatggct taaagccaag aaaaccatag
9301 tataaatctt tttgtgtacc tatgctagtg tttaaatggc agttcgttgt gataaagtat
9361 cagtcacttc aagttttctg tgaaagtttt taattaggtt aaaaataatt ttggcatacg
9421 tctctactca gtttataaag cagttccaca ccatgcaaac aaaactctaa cagcaaaggt
9481 tatcttgacc tgatgttact tgaatctgag agaaagtcat tacttactac tgcactcctg
9541 cttttgtggg aaaaattttc ttcttcccca gaagagttaa cagttgagtg ttcagctcct
9601 gacttacctt taatttagag gcaatattat tactgtttaa gtgattattt gcttaacaca
9661 ggttttattt tgtctttttg ctggtagatt atacaaggga caactttagt gatgaggcat
9721 gtggatgatt tggtgggagt aggtatatac ttagtggaat ggtttatttt atggaagaga
9781 attcattgga ggtgagattg aagtatattg tgaagtggga tttgaacagc acatatgctc
9841 tggtttgctc aaataactgc agtttatgct tacatctaaa ttttgtttct gttacctaaa
9901 cgggagcttc tagaattacg aaggccatac ctgccacatt tataaaataa tggttttatc
9961 cctgccccca aatcatcagg ttcctcgggt ttaagagaag tggtctaata gacaggaata
10021 gaagttgtgg tggaggtgat ttgggataga ctaggtttcc ttatgcaagt ggatatgagc
10081 tcctcataga aaccagacct actgtattag acagtaacct ctaacctcac ctccaagccc
10141 aagtatatgg ccctgctggg ttacctggtg actacatttc ccagattcac tctaaattca
10201 aggtagtgac ccaaataaat tgggaaagga gggggtcaag gaggaaaagc tgttgaaaat
10261 ctttctccta tttaagagaa atatatgccc tagagctgct ccagcaccct tggtttctga
10321 tttttttaat attgaatatg gattagaaga atgaaatcag atgacacctg actgcaaaaa
10381 tgtttataag caaatagcct tcttacattt tggtataaag ctgtgaactt cgtaactttg
10441 taaagcaaga tataaagcaa atacaagagg aaaataaagt acttttacta attgacggtt
10501 tactttcgtt accttgtctg catattcacg gccagccctt tccacgttgg cttagcgagg
10561 aagaaggaaa ctgggtggaa aacacaggat gcctatagat atgccgcagg ccatggtcca
10621 gagaagttta gcaaacaaac agctgcgttc agggttttgt ccacggtcat gcgacaggtc
10681 agttagtgag cagaggagct aggatagctc aatctccact ccattattca ggtaaccggc
10741 ccctcccgtt gtacatgacc catttattct tgatgtcttt tacagcaaca actattcctc
10801 tgccttcctt ttatgtcttg gaaagtatct gagccattct tatgctcaag aaatagcaat
10861 aggcatgatt acaaaattca aaaaaaaaaa
//