Mus musculus coagulation factor XII (Hageman factor) (F12), mRNA

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Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease. [Nat Commun. 2024]
Factor XII signaling via uPAR-integrin β1 axis promotes tubular senescence in diabetic kidney disease.
Elwakiel A, Gupta D, Rana R, Manoharan J, Al-Dabet MM, Ambreen S, Fatima S, Zimmermann S, Mathew A, Li Z, et al. Nat Commun. 2024 Sep 11; 15(1):7963. Epub 2024 Sep 11.
4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model. [Blood. 2024]
4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model.
Ballard-Kordeliski A, Lee RH, O'Shaughnessy EC, Kim PY, Jones SR, Pawlinski R, Flick MJ, Paul DS, Mackman N, Adalsteinsson DA, et al. Blood. 2024 Sep 5; 144(10):1116-1126.
Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation. [Front Pharmacol. 2023]
Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation.
Clermont AC, Murugesan N, Edwards HJ, Lee DK, Bayliss NP, Duckworth EJ, Pethen SJ, Hampton SL, Gailani D, Feener EP. Front Pharmacol. 2023; 14:1287487. Epub 2023 Dec 19.

RefSeq protein product
See the reference protein sequence for coagulation factor XII preproprotein (NP_067464.2).

Protein
Protein sequence from Nucleotide coding region
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Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
coagulation factor XII [Guide to Pharmacology]
coagulation factor XII
Guide to Pharmacology
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
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Nucleotide