The histone demethylase JMJD2C constitutes a novel NFE2 target gene that is required for the survival of JAK2(V617F) mutated cells.
Staehle AM, Peeken JC, Vladimirov G, Hoeness ME, Bojtine Kovacs S, Karantzelis N, Gruender A, Koellerer C, Jutzi JS, Pahl HL, et al. Leukemia. 2023 Apr; 37(4):919-923. Epub 2023 Jan 28.