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Drosophila melanogaster Not1, transcript variant H (Not1), mRNA

NCBI Reference Sequence: NM_001299323.1

FASTA Graphics 

LOCUS       NM_001299323            8191 bp    mRNA    linear   INV 26-DEC-2023
DEFINITION  Drosophila melanogaster Not1, transcript variant H (Not1), mRNA.
ACCESSION   NM_001299323
VERSION     NM_001299323.1
DBLINK      BioProject: PRJNA164
            BioSample: SAMN02803731
KEYWORDS    RefSeq.
SOURCE      Drosophila melanogaster (fruit fly)
  ORGANISM  Drosophila melanogaster
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE   1  (bases 1 to 8191)
  AUTHORS   Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
            Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
            Strelets,V., Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: Impact of
            High-Throughput Data
  JOURNAL   G3 (Bethesda) 5 (8), 1721-1736 (2015)
   PUBMED   26109357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8191)
  AUTHORS   Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
            Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
            Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: The
            Rule-Benders
  JOURNAL   G3 (Bethesda) 5 (8), 1737-1749 (2015)
   PUBMED   26109356
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8191)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
            Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
            Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
            Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
            Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
            Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
  TITLE     The Release 6 reference sequence of the Drosophila melanogaster
            genome
  JOURNAL   Genome Res 25 (3), 445-458 (2015)
   PUBMED   25589440
REFERENCE   4  (bases 1 to 8191)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
            Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
            Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
  TITLE     Sequence finishing and mapping of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1625-1628 (2007)
   PUBMED   17569867
REFERENCE   5  (bases 1 to 8191)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  TITLE     The Release 5.1 annotation of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1586-1591 (2007)
   PUBMED   17569856
  REMARK    Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE   6  (bases 1 to 8191)
  AUTHORS   Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
            Ashburner,M. and Anxolabehere,D.
  TITLE     Combined evidence annotation of transposable elements in genome
            sequences
  JOURNAL   PLoS Comput Biol 1 (2), 166-175 (2005)
   PUBMED   16110336
REFERENCE   7  (bases 1 to 8191)
  AUTHORS   Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
            Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
            Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
            Celniker,S.E., Rubin,G.M. and Karpen,G.H.
  TITLE     Heterochromatic sequences in a Drosophila whole-genome shotgun
            assembly
  JOURNAL   Genome Biol 3 (12), RESEARCH0085 (2002)
   PUBMED   12537574
REFERENCE   8  (bases 1 to 8191)
  AUTHORS   Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
            Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
            Rubin,G.M., Ashburner,M. and Celniker,S.E.
  TITLE     The transposable elements of the Drosophila melanogaster
            euchromatin: a genomics perspective
  JOURNAL   Genome Biol 3 (12), RESEARCH0084 (2002)
   PUBMED   12537573
REFERENCE   9  (bases 1 to 8191)
  AUTHORS   Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
            Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
            Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
            Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
            Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
            Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
            Rubin,G.M. and Lewis,S.E.
  TITLE     Annotation of the Drosophila melanogaster euchromatic genome: a
            systematic review
  JOURNAL   Genome Biol 3 (12), RESEARCH0083 (2002)
   PUBMED   12537572
REFERENCE   10 (bases 1 to 8191)
  AUTHORS   Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
            Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
            Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
            Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
            Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
            Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
            Gibbs,R.A. and Rubin,G.M.
  TITLE     Finishing a whole-genome shotgun: release 3 of the Drosophila
            melanogaster euchromatic genome sequence
  JOURNAL   Genome Biol 3 (12), RESEARCH0079 (2002)
   PUBMED   12537568
REFERENCE   11 (bases 1 to 8191)
  AUTHORS   Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
            Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
            George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
            Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
            Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
            Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
            Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
            Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
            Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
            Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
            Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
            Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
            Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
            Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
            Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
            Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
            Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
            Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
            Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
            Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
            Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
            Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
            Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
            McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
            Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
            Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
            Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
            Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
            Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
            Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
            Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
            Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
            Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
            Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
            Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
            Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
            Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
  TITLE     The genome sequence of Drosophila melanogaster
  JOURNAL   Science 287 (5461), 2185-2195 (2000)
   PUBMED   10731132
REFERENCE   12 (bases 1 to 8191)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
            Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
            Smith,E., Yu,C. and Rubin,G.
  CONSRTM   Berkeley Drosophila Genome Project
  TITLE     Drosophila melanogaster release 4 sequence
  JOURNAL   Unpublished
REFERENCE   13 (bases 1 to 8191)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   14 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   15 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   16 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   17 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2019) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   18 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   19 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   20 (bases 1 to 8191)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2015) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   21 (bases 1 to 8191)
  AUTHORS   Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
            Park,S., Svirskas,R. and Karpen,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
            Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   22 (bases 1 to 8191)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
            Svirskas,R. and Rubin,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
            64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   23 (bases 1 to 8191)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  CONSRTM   Drosophila Heterochromatin Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
            Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
            Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE   24 (bases 1 to 8191)
  AUTHORS   Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
            Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by FlyBase. This
            record is derived from an annotated genomic sequence (NT_033778).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: FlyBase
            Annotation Status   :: Full annotation
            Annotation Version  :: Release 6.54
            URL                 :: http://flybase.org
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8191
                     /organism="Drosophila melanogaster"
                     /mol_type="mRNA"
                     /db_xref="taxon:7227"
                     /chromosome="2R"
                     /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
                     bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
     gene            1..8191
                     /gene="Not1"
                     /locus_tag="Dmel_CG34407"
                     /old_locus_tag="CG1874"
                     /old_locus_tag="CG1884"
                     /old_locus_tag="Dmel_CG1874"
                     /old_locus_tag="Dmel_CG1884"
                     /gene_synonym="anon-EST:Liang-1.29; anon-WO0118547.221;
                     CG1874; CG1884; CG34407; clone 1.29; Dmel\CG34407; NOT;
                     not1; NOT1"
                     /map="45F1-45F4"
                     /db_xref="FLYBASE:FBgn0085436"
                     /db_xref="GeneID:5740252"
     CDS             192..7727
                     /gene="Not1"
                     /locus_tag="Dmel_CG34407"
                     /old_locus_tag="CG1874"
                     /old_locus_tag="CG1884"
                     /old_locus_tag="Dmel_CG1874"
                     /old_locus_tag="Dmel_CG1884"
                     /gene_synonym="anon-EST:Liang-1.29; anon-WO0118547.221;
                     CG1874; CG1884; CG34407; clone 1.29; Dmel\CG34407; NOT;
                     not1; NOT1"
                     /note="CG34407 gene product from transcript CG34407-RH;
                     CG34407-PH; Not1-PH"
                     /codon_start=1
                     /product="Not1, isoform H"
                     /protein_id="NP_001286252.1"
                     /db_xref="FLYBASE:FBpp0308486"
                     /db_xref="GeneID:5740252"
                     /db_xref="FLYBASE:FBgn0085436"
                     /translation="MCPRLRAVAVKALILASKPYAMQLFDSKPYITDSIYDILQFVKE
                     HGLEADRSSLRHLFSVINFSDLVPSVTVQLQAKLLGIQLERQLHSSSFVSNICYAFDQ
                     FFASNQKQSLKPVAVADLVGQVARLTGINKVCECVFALALTHSSYTELKHSARNNLKG
                     SLSELIDSYLGNKGTGPADSGLREISFDLLQYLLCCLSEYVQPQVEAQFLIKLREEFP
                     RQAVPLVLAPFLYGSTTATIAGAGASETDAEAEATTNSNSSSFEADALNEVGIEDIYD
                     HLSEIIFTNQGKNNIMDTSWINLILEIGYEFTSSVEECKNHLCSRERERAELQSKDVA
                     KIVGLMCRRHSSLLDCNVNLPTPANFWPGQGQGGGSNSSGSSQTQITPQQQNPGSSNN
                     NDGSDGNSSSDKKDKKETTEATQTWKPDVFVQALKEVVPQLNWKDVCMELDHPEFVLK
                     DRIGLELLLTILRLATGSNIFPHPECIYRHWANTEGQLSLIATMLKNPDLFSFADFVF
                     SQPALDVLKTAPDADNKEISSWKSLHLVEVLLSIADKGYYTQVHELFKFPAQNCPDVL
                     FLALLNTSPPMTPLRQDLFNQLIPTFLGNHPNSNVILASAWSSNNFQLRSNIMNAMSE
                     WYLRGNEFDQVKLSRILDLAQDLKALSALLNARSFLFIIDLACLASRREYLKLEKWLT
                     DKIREHGEPFMQAIIKVLHRRCPQVINAKVPEDQLPPKQAQLLPETVTTMINCLQTCI
                     NNCMQPEMVEVIMQMTANVAIMANKARAQQQQQPGLVPPPPPTILRGHRGMDLPGGIV
                     PPPPQQPFSGNLNAQMFGPGMDPLTNMSNNLAGLNLSGPNGAFNFGNMLTSPSRLMTP
                     GANPYPLNLMQMPQAPPPPNVGNLGRMLPGGPQQQTPTPTPTAPNPNNPVMADLQIPV
                     SKEVEDEVNSYFQRIYNHQPNPTLSIDEVLDILQRFKESSNRREQEVFLCMLRNLFEE
                     YRFFCQYPEKELQITAQLFGGIIDRNLVPTFVALGLSLRCVLDALRKPDGSKLYYFGV
                     TALDRFRTRLHTYNKYCEHIRSIPHFSDFPPHLIQYVEYGMHGQEPPPQKLIGLSNTI
                     PSAISSGPGTEPIYRNSSMLGNMPAATPGSGPKSNAAVSHATRMKSIANATNIDTLLV
                     ANQEEKVTVPPEPVQDKTAFIFNNLSQLNIPQKCDEIKEIMTKEYWPWLAQYLVLKRA
                     SMEFNFHTLYYNFLDALKNGEINRFVTKETLRNIKVLLRSDKGVINFSDRSLLKNLGH
                     WLGMMTLGRNRPILQLDLDLKSLLAEAYHKGQQELLFVVPFVAKILESSAKSRIFRSP
                     NPWTMGIMYVLAELHQEPDLKLNLKFEIEVLCKTLNLELAKLRQVIYLKDPNRTHRIE
                     EQMSQPKPKQLEPVASAPALPREQQSPAQPPPPPQQQQPPQQQVPPPPSSADVDAQNA
                     AAMMMAAGGANSTPGSVSSPNLPTDSSQVALPPPEPRYSYVDVNVSNFQLIGQQLVLP
                     PNTPFLHANPGIKHMVVNAVERTITDWLQPIVDRSIRIACATTEQIIRKDFALDADEN
                     RMRTAAHQMVRNLAAGMAMITGKDEIARAISQNLHKALLSGLNGMPSMAEIQAAAMQL
                     ASENVELVCAFIQKTSAEKAAAEIDRRLSTDFETRKIAREEGNRFVDAQILTYQQERL
                     PEAVRIKVGAAPATLYAVYSEFARSIPGFQQMSDRDIALFVPKPTDLSQPNVFANDDS
                     MVYGELASKMEAFMNTAIGVPTLQIQASKMHMLLNALIATRRLRDQESAFNLLTRAVE
                     GLTEGLVNMHENMEQMKMYQNIHLRILGLLNNSFGAPNTERAVTKCFFDIREEVRYNV
                     EAARALITSHFVNLNQFDGMLRDCMDNGNNYVAISFGIALLERLIMDDRVINIVSDNE
                     FMATVELLGRLTQHRHRYPECIVNAIDTLWSGNFNSSSDYSPFNGNDRYLSGASHYIH
                     SGMHHVRSCDTDDPPGLQEKTEFLLKDWVALYTQQNQQSTRDARNFGAFVQKMNTYGI
                     LKTDDLITRFFRQATHICTDVVYRMFAEPSLPINQAKNKIFQWIDAFVHLIAMLVRHS
                     GEAGNPTTKINLLNKVLGIVLGTLIKDHEMRGVSFQQVGYHRFFMMLFMELCTADVIL
                     ESLMHSIVSAFAYTYHLLNPSVAPGFCFAWLELISHRVFLGRILVQIPGQKGWPLYAQ
                     LLQDLFKYLAPFLRNTELGKPVQLLYKGTLRVLLVLLHDFPEFLCDYHFGFCDTIPPN
                     CVQMRNIILSAFPRNMRLPDPFTPNLKVDMLSDSSNAPKVLSSYIMNIQPANFKKDLD
                     SYLKARAPVTFLSELRGHLQVTSEPGTRYNMALMNALVMYVGTQAIALIRNKNFVPNT
                     SNIAHSAHMDIFQNLAVDLDTEGRYLFLNAIANQLRYPNSHTHYFSCAVLHLFAEANS
                     EAIQEQITRVLLERLIVNRPHPWGLLITFIELIKNPIYKFWDHDFVHCAPEITKLFES
                     VARSCLAKSNVTQQLNMPVVDGEGQEVATIN"
ORIGIN      
        1 gttactttac atcttgccct gtatccgtaa acacatatcc aattgtacag agaaaagttg
       61 agacactcac agaacataat agaacctgtc aaaatttcca agtttgcgat gaaaatcaca
      121 taaaaaaaaa tcccggtcac cgcagaatct gaggaatcgt ttgaaacata cactgtccct
      181 tatacagtga tatgtgtccc agattgcggg cagtcgctgt caaggcactt atattggctt
      241 ccaaacccta cgcaatgcag ctctttgatt ctaaaccata cattactgat agcatttacg
      301 acatcttgca gttcgttaaa gagcacggcc tggaagcgga tcgcagcagc ctgcgccacc
      361 tgttctccgt gatcaacttc agcgatctcg tgccatcagt tacggtccag ctgcaggcga
      421 agctcctggg catccagttg gagcgtcagc ttcacagttc atcgtttgtg tccaacatct
      481 gctacgcttt tgaccagttc ttcgccagca accagaagca gtccctgaag cctgttgcgg
      541 tagcggatct cgttggccag gtcgcccgac tgaccggcat caacaaggtt tgtgagtgcg
      601 tctttgcctt ggccttgacc cactcctcgt acacagaact caaacattct gccaggaaca
      661 acctaaaagg tagcctcagc gaacttatag actcttactt gggtaataaa ggcaccggcc
      721 cagccgacag cggtctccgg gagatctcct tcgatctact gcagtatttg ttgtgctgcc
      781 ttagcgagta cgtacaaccg caggtggaag cacagttttt gatcaagctt cgtgaggagt
      841 ttccgcgcca ggcggtaccg ctggttctag cgccgttcct ttacggctcg acgacggcga
      901 cgattgcggg agcaggtgcc agcgaaacgg atgcggaggc cgaagcgacg actaatagca
      961 acagctccag tttcgaagca gatgctttga acgaggtggg aatcgaggat atttatgacc
     1021 atttaagcga gataatattc accaaccagg gcaaaaataa tattatggac acatcttgga
     1081 ttaatctaat ccttgaaatc ggttatgaat ttacatcgag cgttgaagag tgtaagaatc
     1141 atttgtgttc ccgcgagcga gaacgcgctg agctccagtc caaagatgtc gccaagatcg
     1201 tgggtcttat gtgccgacgg cactcctccc tgctcgattg taatgtgaat ctaccgacgc
     1261 cggcgaactt ctggcctggt cagggacagg gcggtggcag caacagcagt ggctcttcgc
     1321 agacacaaat cactccgcag caacagaacc cgggcagcag taacaacaac gatggcagcg
     1381 atggcaattc gtccagtgat aagaaggaca agaaggagac gacggaggcc acgcaaactt
     1441 ggaagccaga tgtctttgtg caggcgctca aggaggtggt gcctcagctc aactggaagg
     1501 acgtgtgcat ggaacttgat catcccgagt tcgtgctgaa ggatcgcatc ggtttggagc
     1561 ttttgctcac catccttcgg ctggccactg gctctaacat atttccacat ccagaatgca
     1621 tttaccgtca ctgggcaaac acggaaggtc agctgtcgct tatcgcgaca atgctgaaga
     1681 acccggatct cttttccttc gccgactttg tatttagcca gccagcgttg gatgtgctta
     1741 agacggctcc ggatgcggac aataaggaga tctcgtcctg gaagtcgctt cacctggtgg
     1801 aggtgctgct ctccattgcg gacaagggat actatacgca ggtccatgag ctattcaagt
     1861 tcccagcgca gaactgtccc gatgtgctat ttttggcctt attgaacaca agtccgccta
     1921 tgacgccact gcgtcaggat ctgtttaacc aactgatacc aacgttcctt ggcaaccatc
     1981 ccaactcgaa cgtgatcttg gccagcgcct ggagctcgaa caacttccaa cttcgttcca
     2041 atatcatgaa tgctatgtcc gagtggtatc tccgaggcaa tgagttcgat caggtgaaac
     2101 tgtcgcgcat cctggatctt gcccaggatt taaaagcgct atcagcgctg ctcaacgccc
     2161 gttcattttt attcattatc gacctggctt gccttgcctc tcggcgcgag tacctgaagc
     2221 tggaaaagtg gcttaccgat aaaattcgcg aacatggaga gccttttatg caggctataa
     2281 tcaaggttct gcaccgccgc tgcccgcagg ttatcaacgc aaaagtgcca gaggatcagc
     2341 tgcctcccaa gcaggcgcag cttttgcccg agacagttac caccatgatc aactgtctgc
     2401 aaacgtgcat caataactgc atgcagccgg agatggtcga agtcatcatg caaatgaccg
     2461 cgaacgtggc gattatggct aacaaggcgc gtgcccaaca gcagcagcag ccaggattgg
     2521 ttccgccgcc tccaccaaca attctgcgcg gccatcgtgg tatggatctg cctggaggca
     2581 tagtccctcc gccaccgcag caaccgttct ccggaaacct caacgcgcag atgtttggac
     2641 caggaatgga tccgctaacg aatatgtcca acaacttagc cggcctcaac ctcagcggcc
     2701 cgaacggagc atttaatttt ggaaacatgc taacttctcc atcgcgtctg atgactccgg
     2761 gagccaatcc ctatccgctg aacctcatgc agatgccgca ggctccgcca ccacccaacg
     2821 taggaaacct aggccgcatg ctgccagggg gtccacaaca gcagactcca acgccgactc
     2881 caacggcccc caatccaaac aaccctgtga tggccgatct ccagatacct gtgtcaaagg
     2941 aagttgaaga cgaggtcaac tcatactttc agcgcatcta caaccaccag ccgaatccaa
     3001 cgctgtccat cgatgaagtg ctggacattt tgcaaagatt taaagagtca agtaaccggc
     3061 gcgagcagga agtctttttg tgcatgctgc gcaatctgtt cgaggaatat cgctttttct
     3121 gtcaataccc agagaaagag ctacagatta ctgcgcagct atttggtggc attattgatc
     3181 gtaacctggt gcccactttt gttgcactgg gcctttctct gcgctgtgtc ttggatgccc
     3241 tccgcaagcc cgatggatct aagctttact atttcggtgt gacggcactg gacagattca
     3301 gaactcgatt gcacacctac aacaaatact gcgagcatat ccgctccatt cctcacttct
     3361 ctgacttccc gccgcacctt attcagtatg tggaatacgg aatgcacggc caggagccgc
     3421 cgccgcagaa gttgattgga ctcagcaata cgattccttc ggcgatatct agcggaccag
     3481 gaacggaacc aatttacagg aatagctcca tgttaggtaa tatgcccgct gccaccccgg
     3541 gatcgggacc gaaatcaaac gctgctgtat cgcatgccac gagaatgaag tccatcgcca
     3601 atgccaccaa tatcgacaca cttttggtgg ccaaccagga agagaaagtg actgtgccac
     3661 cagagcctgt gcaggacaaa actgccttta ttttcaacaa cttgagccag ctgaacatac
     3721 cgcagaagtg cgatgagata aaggagatta tgaccaagga gtattggccg tggctagcgc
     3781 aatatctggt cctcaaacgc gcatcaatgg agttcaactt ccacacacta tattacaact
     3841 ttttggatgc ccttaaaaac ggcgagatca accgattcgt aaccaaagag accctacgca
     3901 acatcaaggt actcttgcgc tccgataagg gagttattaa tttctccgat cgaagtctgt
     3961 tgaagaacct cggacactgg ttgggcatga tgaccttagg tcgcaatcgc cccatcctgc
     4021 agttggatct ggatcttaaa tcccttttgg ctgaggctta ccacaagggc cagcaggaac
     4081 tgctttttgt ggttcctttc gtagccaaga tccttgagtc atccgccaag tctcgcatct
     4141 tccgatcgcc caatccatgg acaatgggta tcatgtacgt gcttgctgag cttcaccagg
     4201 agccagacct taagctgaac ctgaagtttg aaatcgaagt actctgtaaa acacttaatc
     4261 tggagttggc caagttgcga caagtgatct acctgaagga tcccaatcga actcaccgga
     4321 ttgaagagca gatgtcgcaa ccaaaaccga aacaacttga gccagtggct tctgcgccag
     4381 ctctaccgcg tgaacagcaa tccccggcac aacctccgcc accaccacaa cagcagcaac
     4441 caccgcagca gcaggtacct ccaccgccat cctctgcgga cgtggacgct caaaatgcgg
     4501 ccgctatgat gatggcagcg ggcggagcta atagtactcc tggatcggta tcttcgccca
     4561 atctacccac cgattccagc caggtggcac taccgccacc agagccgcgc tattcatacg
     4621 tggacgtaaa cgtgagcaac ttccagctta ttggtcagca gttggtactg ccacccaata
     4681 ctccgttcct gcacgccaat cccggaatca aacacatggt cgtcaacgcc gtggagcgca
     4741 cgataaccga ctggttgcag cctattgtgg accgaagcat ccgcattgcc tgtgccacca
     4801 ccgagcagat catccgcaag gacttcgccc tggatgctga cgagaaccga atgcgcactg
     4861 ccgctcatca gatggtacga aaccttgccg ccggcatggc catgattacc ggtaaggatg
     4921 agatagcgcg tgctattagc cagaatctgc acaaggcctt gctgtcgggt ctaaatggga
     4981 tgcccagcat ggctgagatc caagctgctg ctatgcagtt agccagcgaa aatgttgagc
     5041 tagtttgcgc tttcattcag aaaacatctg ctgaaaaggc agccgcagag atcgataggc
     5101 gtctaagcac cgatttcgag accagaaaaa ttgctcgtga agagggcaac cgctttgtgg
     5161 acgcccagat cctcacctat caacaggagc gtcttccaga agcagtgcgc atcaaggtgg
     5221 gcgcggctcc agctacactt tatgctgtgt actcggagtt cgctagaagc atacctggct
     5281 tccagcagat gagcgatcgc gatattgccc tgtttgtgcc caagccgacg gatttgtctc
     5341 agccaaatgt gtttgctaat gatgatagca tggtatacgg ggaactggct agcaaaatgg
     5401 aggccttcat gaacacggca atcggagtgc cgacactcca gatccaggct agcaagatgc
     5461 acatgctact caacgccctg atagcgacgc gtcgactgcg tgaccaagag tctgccttta
     5521 atctgctgac ccgcgcggtc gagggtttga ccgaaggatt ggtcaatatg catgaaaaca
     5581 tggagcaaat gaagatgtac caaaacatcc atctccgtat ccttggcttg ctgaacaata
     5641 gtttcggtgc tccaaacaca gagcgagcgg taacaaagtg tttcttcgat atccgagagg
     5701 aggtgcgata taacgtggag gcagctcgcg ctttgattac gtcgcacttt gtcaatctga
     5761 atcagtttga cggaatgcta cgcgactgca tggacaacgg aaacaattat gtggccatat
     5821 cgttcggtat cgcactgctg gagcgcctca tcatggacga tcgagtgatt aatattgttt
     5881 cggacaacga attcatggca actgttgagc tgctaggtag gctcactcag catcgccatc
     5941 ggtatccaga atgcattgtg aatgctattg atacgctctg gagcggaaac tttaactcga
     6001 gcagcgacta cagcccgttc aacggcaatg atcgttactt gtcgggagcc tcccattaca
     6061 tccactccgg catgcatcac gtaaggtcat gcgatacaga tgatccgccg ggcttacaag
     6121 agaagacgga gtttctgctt aaggattggg ttgcactgta cacgcaacag aaccagcagt
     6181 caacgcgcga tgcacgcaac ttcggtgcat ttgttcagaa gatgaacaca tatggtatcc
     6241 tgaaaacgga cgacttgatc acccgttttt tccgccaggc cacacacatt tgcacggatg
     6301 tggtgtacag aatgttcgcc gagccgagtt taccaatcaa ccaggccaaa aacaagatat
     6361 tccagtggat cgatgcgttc gtccatctga ttgcaatgct cgtgcgacac tcaggcgaag
     6421 caggtaatcc aaccaccaag atcaacctgt taaacaaggt gctgggcatt gtgctgggaa
     6481 cgctgattaa ggaccatgag atgcgtggcg ttagcttcca gcaggttggc taccatcgct
     6541 tcttcatgat gctgttcatg gagctgtgca cggccgatgt gattctcgag tccctgatgc
     6601 acagtattgt gtcggccttc gcctacacat atcacttgtt gaatcccagc gtggctccgg
     6661 gattctgctt tgcttggttg gagctcattt cgcatcgcgt cttcctgggc cgcatcctgg
     6721 tccaaattcc cgggcaaaag ggctggccac tttacgctca gttgctgcag gaccttttta
     6781 aatatcttgc gcccttctta cgcaacactg agctcggcaa accagtccag cttttgtaca
     6841 aggggacgct acgtgttctg ctcgttctgc ttcacgactt cccggagttc ttgtgcgact
     6901 atcattttgg gttctgtgac accatcccgc ccaattgcgt ccagatgcgt aacatcatcc
     6961 tgtcggcgtt tccgcgcaac atgcgcttgc ccgatccctt cacgcccaac ctaaaagtgg
     7021 acatgctgtc ggacagtagt aatgcgccta aggtgctcag tagctacatt atgaacatcc
     7081 agcccgcgaa ctttaagaag gatttggact cgtacctcaa ggcccgggcg ccagttactt
     7141 ttctatcgga attacgtggt cacttgcagg tgacaagcga gccaggaact cgttacaaca
     7201 tggcactgat gaatgctctg gtcatgtatg tgggaactca ggcgattgct ttgatcagaa
     7261 acaaaaactt tgtgcccaac acctcgaaca tagcacacag cgcccacatg gatatcttcc
     7321 agaatcttgc tgttgacttg gatacggagg gtcgctatct gttcttgaat gcgattgcga
     7381 accagttgcg ctatcccaac agccacacgc actacttcag ctgtgcggtg ctgcatctgt
     7441 ttgccgaggc caactcggag gcaattcagg agcagatcac tcgcgtactt ctggaacgat
     7501 tgatcgtgaa ccgcccgcat ccttggggac tgttgatcac ttttattgag ctgatcaaaa
     7561 atcccatcta caagttctgg gaccatgact ttgtgcactg tgcgccagag atcaccaagc
     7621 tctttgaatc ggtggcccgt tcctgtctgg ccaagtcgaa cgtcacccag cagttgaaca
     7681 tgcccgtcgt cgatggcgag ggccaggagg tagccaccat caactgagaa aacgccaccg
     7741 tccgacgctt ctgcctggag gtctgcgcga gacccagacg caggcagtag ctgcctgggc
     7801 agcacaccac caccaccacc cacaacacca cacagtacag cgttcattga attctactaa
     7861 ccattactgt gtttagttct tagcaaatcg ttttaaggag acagtgaaat cagcaacagc
     7921 acacacaaac attaacaaaa caaccgcaac aataagcata gggaagggaa acagcaggcc
     7981 aagccaattg gtgtgctgtg ccggaaaccg aaattcgaca tgtatttaaa cgaacggaag
     8041 cgatatttta aatgcctccc ccttcgtcgg ggaatgttac aaatttttaa ttgagttgta
     8101 ttataaatgg tagatgaagg cgttaaagtg ttgatgacag atactgtgta aagaaatcaa
     8161 tcaaacagat aaaaacagaa aagcgaaaaa c
//
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