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Drosophila melanogaster suppressor of variegation 3-3, transcript variant C (Su(var)3-3), mRNA

NCBI Reference Sequence: NM_001275171.1

FASTA Graphics 

LOCUS       NM_001275171            3555 bp    mRNA    linear   INV 26-DEC-2023
DEFINITION  Drosophila melanogaster suppressor of variegation 3-3, transcript
            variant C (Su(var)3-3), mRNA.
ACCESSION   NM_001275171
VERSION     NM_001275171.1
DBLINK      BioProject: PRJNA164
            BioSample: SAMN02803731
KEYWORDS    RefSeq.
SOURCE      Drosophila melanogaster (fruit fly)
  ORGANISM  Drosophila melanogaster
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora.
REFERENCE   1  (bases 1 to 3555)
  AUTHORS   Matthews,B.B., Dos Santos,G., Crosby,M.A., Emmert,D.B., St
            Pierre,S.E., Gramates,L.S., Zhou,P., Schroeder,A.J., Falls,K.,
            Strelets,V., Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: Impact of
            High-Throughput Data
  JOURNAL   G3 (Bethesda) 5 (8), 1721-1736 (2015)
   PUBMED   26109357
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3555)
  AUTHORS   Crosby,M.A., Gramates,L.S., Dos Santos,G., Matthews,B.B., St
            Pierre,S.E., Zhou,P., Schroeder,A.J., Falls,K., Emmert,D.B.,
            Russo,S.M. and Gelbart,W.M.
  CONSRTM   FlyBase Consortium
  TITLE     Gene Model Annotations for Drosophila melanogaster: The
            Rule-Benders
  JOURNAL   G3 (Bethesda) 5 (8), 1737-1749 (2015)
   PUBMED   26109356
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3555)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Wan,K.H., Park,S., Mendez,I.,
            Galle,S.E., Booth,B.W., Pfeiffer,B.D., George,R.A., Svirskas,R.,
            Krzywinski,M., Schein,J., Accardo,M.C., Damia,E., Messina,G.,
            Mendez-Lago,M., de Pablos,B., Demakova,O.V., Andreyeva,E.N.,
            Boldyreva,L.V., Marra,M., Carvalho,A.B., Dimitri,P., Villasante,A.,
            Zhimulev,I.F., Rubin,G.M., Karpen,G.H. and Celniker,S.E.
  TITLE     The Release 6 reference sequence of the Drosophila melanogaster
            genome
  JOURNAL   Genome Res 25 (3), 445-458 (2015)
   PUBMED   25589440
REFERENCE   4  (bases 1 to 3555)
  AUTHORS   Hoskins,R.A., Carlson,J.W., Kennedy,C., Acevedo,D., Evans-Holm,M.,
            Frise,E., Wan,K.H., Park,S., Mendez-Lago,M., Rossi,F.,
            Villasante,A., Dimitri,P., Karpen,G.H. and Celniker,S.E.
  TITLE     Sequence finishing and mapping of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1625-1628 (2007)
   PUBMED   17569867
REFERENCE   5  (bases 1 to 3555)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  TITLE     The Release 5.1 annotation of Drosophila melanogaster
            heterochromatin
  JOURNAL   Science 316 (5831), 1586-1591 (2007)
   PUBMED   17569856
  REMARK    Erratum:[Science. 2007 Sep 7;317(5843):1325]
REFERENCE   6  (bases 1 to 3555)
  AUTHORS   Quesneville,H., Bergman,C.M., Andrieu,O., Autard,D., Nouaud,D.,
            Ashburner,M. and Anxolabehere,D.
  TITLE     Combined evidence annotation of transposable elements in genome
            sequences
  JOURNAL   PLoS Comput Biol 1 (2), 166-175 (2005)
   PUBMED   16110336
REFERENCE   7  (bases 1 to 3555)
  AUTHORS   Hoskins,R.A., Smith,C.D., Carlson,J.W., Carvalho,A.B., Halpern,A.,
            Kaminker,J.S., Kennedy,C., Mungall,C.J., Sullivan,B.A.,
            Sutton,G.G., Yasuhara,J.C., Wakimoto,B.T., Myers,E.W.,
            Celniker,S.E., Rubin,G.M. and Karpen,G.H.
  TITLE     Heterochromatic sequences in a Drosophila whole-genome shotgun
            assembly
  JOURNAL   Genome Biol 3 (12), RESEARCH0085 (2002)
   PUBMED   12537574
REFERENCE   8  (bases 1 to 3555)
  AUTHORS   Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J.,
            Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E.,
            Rubin,G.M., Ashburner,M. and Celniker,S.E.
  TITLE     The transposable elements of the Drosophila melanogaster
            euchromatin: a genomics perspective
  JOURNAL   Genome Biol 3 (12), RESEARCH0084 (2002)
   PUBMED   12537573
REFERENCE   9  (bases 1 to 3555)
  AUTHORS   Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S.,
            Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E.,
            Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L.,
            Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D.,
            Drysdale,R.A., Harris,N.L., Richter,J., Russo,S., Schroeder,A.J.,
            Shu,S.Q., Stapleton,M., Yamada,C., Ashburner,M., Gelbart,W.M.,
            Rubin,G.M. and Lewis,S.E.
  TITLE     Annotation of the Drosophila melanogaster euchromatic genome: a
            systematic review
  JOURNAL   Genome Biol 3 (12), RESEARCH0083 (2002)
   PUBMED   12537572
REFERENCE   10 (bases 1 to 3555)
  AUTHORS   Celniker,S.E., Wheeler,D.A., Kronmiller,B., Carlson,J.W.,
            Halpern,A., Patel,S., Adams,M., Champe,M., Dugan,S.P., Frise,E.,
            Hodgson,A., George,R.A., Hoskins,R.A., Laverty,T., Muzny,D.M.,
            Nelson,C.R., Pacleb,J.M., Park,S., Pfeiffer,B.D., Richards,S.,
            Sodergren,E.J., Svirskas,R., Tabor,P.E., Wan,K., Stapleton,M.,
            Sutton,G.G., Venter,C., Weinstock,G., Scherer,S.E., Myers,E.W.,
            Gibbs,R.A. and Rubin,G.M.
  TITLE     Finishing a whole-genome shotgun: release 3 of the Drosophila
            melanogaster euchromatic genome sequence
  JOURNAL   Genome Biol 3 (12), RESEARCH0079 (2002)
   PUBMED   12537568
REFERENCE   11 (bases 1 to 3555)
  AUTHORS   Adams,M.D., Celniker,S.E., Holt,R.A., Evans,C.A., Gocayne,J.D.,
            Amanatides,P.G., Scherer,S.E., Li,P.W., Hoskins,R.A., Galle,R.F.,
            George,R.A., Lewis,S.E., Richards,S., Ashburner,M., Henderson,S.N.,
            Sutton,G.G., Wortman,J.R., Yandell,M.D., Zhang,Q., Chen,L.X.,
            Brandon,R.C., Rogers,Y.H., Blazej,R.G., Champe,M., Pfeiffer,B.D.,
            Wan,K.H., Doyle,C., Baxter,E.G., Helt,G., Nelson,C.R., Gabor,G.L.,
            Abril,J.F., Agbayani,A., An,H.J., Andrews-Pfannkoch,C., Baldwin,D.,
            Ballew,R.M., Basu,A., Baxendale,J., Bayraktaroglu,L., Beasley,E.M.,
            Beeson,K.Y., Benos,P.V., Berman,B.P., Bhandari,D., Bolshakov,S.,
            Borkova,D., Botchan,M.R., Bouck,J., Brokstein,P., Brottier,P.,
            Burtis,K.C., Busam,D.A., Butler,H., Cadieu,E., Center,A.,
            Chandra,I., Cherry,J.M., Cawley,S., Dahlke,C., Davenport,L.B.,
            Davies,P., de Pablos,B., Delcher,A., Deng,Z., Mays,A.D., Dew,I.,
            Dietz,S.M., Dodson,K., Doup,L.E., Downes,M., Dugan-Rocha,S.,
            Dunkov,B.C., Dunn,P., Durbin,K.J., Evangelista,C.C., Ferraz,C.,
            Ferriera,S., Fleischmann,W., Fosler,C., Gabrielian,A.E., Garg,N.S.,
            Gelbart,W.M., Glasser,K., Glodek,A., Gong,F., Gorrell,J.H., Gu,Z.,
            Guan,P., Harris,M., Harris,N.L., Harvey,D., Heiman,T.J.,
            Hernandez,J.R., Houck,J., Hostin,D., Houston,K.A., Howland,T.J.,
            Wei,M.H., Ibegwam,C., Jalali,M., Kalush,F., Karpen,G.H., Ke,Z.,
            Kennison,J.A., Ketchum,K.A., Kimmel,B.E., Kodira,C.D., Kraft,C.,
            Kravitz,S., Kulp,D., Lai,Z., Lasko,P., Lei,Y., Levitsky,A.A.,
            Li,J., Li,Z., Liang,Y., Lin,X., Liu,X., Mattei,B., McIntosh,T.C.,
            McLeod,M.P., McPherson,D., Merkulov,G., Milshina,N.V., Mobarry,C.,
            Morris,J., Moshrefi,A., Mount,S.M., Moy,M., Murphy,B., Murphy,L.,
            Muzny,D.M., Nelson,D.L., Nelson,D.R., Nelson,K.A., Nixon,K.,
            Nusskern,D.R., Pacleb,J.M., Palazzolo,M., Pittman,G.S., Pan,S.,
            Pollard,J., Puri,V., Reese,M.G., Reinert,K., Remington,K.,
            Saunders,R.D., Scheeler,F., Shen,H., Shue,B.C., Siden-Kiamos,I.,
            Simpson,M., Skupski,M.P., Smith,T., Spier,E., Spradling,A.C.,
            Stapleton,M., Strong,R., Sun,E., Svirskas,R., Tector,C., Turner,R.,
            Venter,E., Wang,A.H., Wang,X., Wang,Z.Y., Wassarman,D.A.,
            Weinstock,G.M., Weissenbach,J., Williams,S.M., WoodageT,
            Worley,K.C., Wu,D., Yang,S., Yao,Q.A., Ye,J., Yeh,R.F.,
            Zaveri,J.S., Zhan,M., Zhang,G., Zhao,Q., Zheng,L., Zheng,X.H.,
            Zhong,F.N., Zhong,W., Zhou,X., Zhu,S., Zhu,X., Smith,H.O.,
            Gibbs,R.A., Myers,E.W., Rubin,G.M. and Venter,J.C.
  TITLE     The genome sequence of Drosophila melanogaster
  JOURNAL   Science 287 (5461), 2185-2195 (2000)
   PUBMED   10731132
REFERENCE   12 (bases 1 to 3555)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Pfeiffer,B., Frise,E., George,R.,
            Hoskins,R., Stapleton,M., Pacleb,J., Park,S., Svirskas,R.,
            Smith,E., Yu,C. and Rubin,G.
  CONSRTM   Berkeley Drosophila Genome Project
  TITLE     Drosophila melanogaster release 4 sequence
  JOURNAL   Unpublished
REFERENCE   13 (bases 1 to 3555)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   14 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (13-DEC-2023) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   15 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2022) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   16 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (19-OCT-2022) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   17 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (20-APR-2020) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   18 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (22-APR-2019) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   19 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (24-MAY-2018) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   20 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-DEC-2016) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   21 (bases 1 to 3555)
  CONSRTM   FlyBase
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2015) FlyBase, Harvard University, Biological
            Laboratories, 16 Divinity Ave, Cambridge, MA 02138, USA
REFERENCE   22 (bases 1 to 3555)
  AUTHORS   Celniker,S., Carlson,J., Kennedy,C., Wan,K., Frise,E., Hoskins,R.,
            Park,S., Svirskas,R. and Karpen,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One #Cyclotron RoadOne
            Cyclotron Road, MS 64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   23 (bases 1 to 3555)
  AUTHORS   Celniker,S., Carlson,J., Wan,K., Frise,E., Hoskins,R., Park,S.,
            Svirskas,R. and Rubin,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2006) Berkeley Drosophila Genome Project,
            Lawrence Berkeley National Laboratory, One Cyclotron Road, MS
            64-121, Berkeley, CA 94720, USA
  REMARK    Direct Submission
REFERENCE   24 (bases 1 to 3555)
  AUTHORS   Smith,C.D., Shu,S., Mungall,C.J. and Karpen,G.H.
  CONSRTM   Drosophila Heterochromatin Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2006) Drosophila Heterochromatin Genome Project,
            Ernest Orlando Lawrence Berkeley National Laboratory, 1 Cyclotron
            Road, Mailstop 64-121, Berkeley, CA 94720, USA
REFERENCE   25 (bases 1 to 3555)
  AUTHORS   Adams,M.D., Celniker,S.E., Gibbs,R.A., Rubin,G.M. and Venter,C.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAR-2000) Celera Genomics, 45 West Gude Drive,
            Rockville, MD 20850, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by FlyBase. This
            record is derived from an annotated genomic sequence (NT_037436).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: FlyBase
            Annotation Status   :: Full annotation
            Annotation Version  :: Release 6.54
            URL                 :: http://flybase.org
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3555
                     /organism="Drosophila melanogaster"
                     /mol_type="mRNA"
                     /db_xref="taxon:7227"
                     /chromosome="3L"
                     /genotype="y[1]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2]
                     bw[1] sp[1]; LysC[1] MstProx[1] GstD5[1] Rh6[1]"
     gene            1..3555
                     /gene="Su(var)3-3"
                     /locus_tag="Dmel_CG17149"
                     /gene_synonym="CG17149; dLsd1; dLSD1; Dmel/HDM; Dmel/LSD1;
                     Dmel\CG17149; Dmel\LSD1; Hdm; lsd1; Lsd1; LSD1;
                     Su(Var)3-3; SU(VAR)3-3; Su-var(3)3; Suvar(3)3"
                     /note="Suppressor of variegation 3-3"
                     /map="77A3-77A3"
                     /db_xref="FLYBASE:FBgn0260397"
                     /db_xref="GeneID:40217"
     CDS             370..2982
                     /gene="Su(var)3-3"
                     /locus_tag="Dmel_CG17149"
                     /gene_synonym="CG17149; dLsd1; dLSD1; Dmel/HDM; Dmel/LSD1;
                     Dmel\CG17149; Dmel\LSD1; Hdm; lsd1; Lsd1; LSD1;
                     Su(Var)3-3; SU(VAR)3-3; Su-var(3)3; Suvar(3)3"
                     /EC_number="1.-.-.-"
                     /EC_number="1.14.99.66"
                     /note="CG17149 gene product from transcript CG17149-RC;
                     CG17149-PC; Su(var)3-3-PC; lysine-specific demethylase 1;
                     histone demethylase; histone lysine-specific demethylase
                     1; flavoprotein"
                     /codon_start=1
                     /product="suppressor of variegation 3-3, isoform C"
                     /protein_id="NP_001262100.1"
                     /db_xref="FLYBASE:FBpp0304939"
                     /db_xref="GeneID:40217"
                     /db_xref="FLYBASE:FBgn0260397"
                     /translation="MKPTQFGGSSSKMTEPIEYVTLISDDSDGEPTPKRNVNHPPSAL
                     SAPNPGQKQKHPDEDSNDAPATSDERRTSRRNRPKVDYSNRPSGSGDTASNDKSGSAS
                     MGPNNQQAERRSQSQTRKSEANATSSSVSGPSAGNSRPSQNGDSKDRDAGTPTVLSGQ
                     EGAVFQSRLPFNKMTPNEEACFPDISRSGILGHRVFLNIRNSLLHMWVDNPKIQLSFE
                     IALKNLPPPFDSEPSLRLKPIPAKKLGKVIVIGAGISGLAVAHQLQQFGMDVIVLEAR
                     DRVGGRISTFRKNSYIADVGAMVVTGVYGNPMTILSKQIGMDLVPIQQTCPLYGPDGK
                     PVPKEKDDVIEREFNRLLESASYLSHRLDFNYAGDCPVSLGDALEWIISMQEMQVMHK
                     RGQHMQEIIATQTKIIEQRRRLKTLRDTIGKLKNEHLAMINQRKPKGTDGDLKYCYQE
                     FNIRNTQIKMEETISTFHDLHAEEKQMLAKLHELEQNRPSDVYLSSRDRLILDWHFAN
                     LEFANATRLNNLSLKHWDQDDDFEFIGHHTTVRNGYSCVPVALTENLDIRVNSAVKEI
                     KYGTKGVEVVAENLKTSNSQMTYKADLVVCTLTLGVLKVAVAHKESQQSNTVKFDPPL
                     PDWKQQAIKRLGFGNLNKVVLCFDRIFWDPNANLFGHVGSTTASRGEMFLFWSISSSP
                     VLLALVAGMAANLVESVTDDIIIGRCMSVLKNIFGNTSVPQPKETVVTRWRSDPWARG
                     SYSYVSVGSSGSDYDLLAAPVIPPSSKDAEGLPRLFFAGEHTIRNYPATVHGAYLSGL
                     REAGRIADYYLGYPEGTPPDIGYSVAEAANLVSVGNVVKLRDLSPNLSDSSPSSKKSE
                     ENSNSNTADSTELQ"
ORIGIN      
        1 aagagatgtt ggtggcgttg tgcggctgcc acaccgccag aacggtataa acaattttta
       61 tattttgcac ttttaaatgt cggaaaatca atctgtgagc caacctaata tgaaaagcga
      121 cgcatggatc agctgataca gcatttgata ataatacttc attgtcatca gagaagcagg
      181 gagtttagac caaaaaaaaa aactacaccc gcagtccgat cctcaaaacg tgtgataata
      241 aaatcacgga acaatcagaa aaatatcgaa agaataatgc ggcaatattc cggtttggtg
      301 gactaaagaa ttcgtgattt tcgaacggcc aacttttcag tgtcccggtg gcagttccat
      361 aatccggaga tgaaacccac ccagttcgga ggcagtagct ccaagatgac cgagccaatt
      421 gagtatgtga cgctaattag cgacgattcc gatggtgagc ccacgcccaa aagaaacgtc
      481 aatcacccgc cgtcggcatt gtcagcaccc aatcctggtc agaaacaaaa gcacccggat
      541 gaggactcaa atgacgcacc tgccaccagc gatgagcgac gcacaagtag gcgcaatcgg
      601 ccaaaagtgg attatagtaa caggcctagt ggaagtggag acaccgcctc caatgacaag
      661 tcaggatcgg catccatggg acctaacaac cagcaagcag agcgtcgcag ccaaagccaa
      721 acccgcaagt cagaagccaa tgctacctcc tcctccgtgt ccggacccag tgccggaaat
      781 tccagaccgt cccagaacgg agattccaag gaccgggatg ccggcacgcc cacggttttg
      841 tctggccaag agggcgccgt cttccaatct cgcctgccat ttaacaaaat gacacccaac
      901 gaagaggcct gctttccgga catcagtcgc tcgggcattc tcggccatcg ggtattcctc
      961 aacattcgta acagcctctt gcacatgtgg gtggacaatc ccaagatcca gctgagcttc
     1021 gagatcgccc tgaagaacct gccgccgcca ttcgacagcg agcccagttt gcgacttaag
     1081 cctatacccg ccaaaaagct gggcaaagtc atagtgattg gggcagggat ctccggctta
     1141 gcagtggcac accagttgca gcagttcggc atggatgtga tcgtcttgga agcgcgggat
     1201 cgggtagggg gacggatatc tacgtttcgg aagaacagct atattgccga tgtgggagca
     1261 atggtggtta ccggcgtcta tggcaatcca atgacgatcc tcagcaagca gatcggtatg
     1321 gacctagttc ccatccagca gacatgtcca ctttacggcc cagatggaaa gcccgtgccc
     1381 aaggagaagg atgacgtgat cgagagagaa tttaaccgac tgctggaatc agccagctac
     1441 ctgtcccacc gccttgattt taactacgcc ggcgattgcc cagtttcgct gggcgatgcc
     1501 ttggagtgga taatcagtat gcaggagatg caggtgatgc acaaacgggg gcagcacatg
     1561 caggagatca tagccaccca aacgaagatc attgaacagc gtcgtcgact gaaaaccctt
     1621 agagatacca tcggcaaact aaagaatgag cacttggcaa tgatcaacca gcggaaaccc
     1681 aaaggcacgg atggcgatct gaaatactgt taccaagagt ttaacattcg gaacacccag
     1741 atcaaaatgg aggaaacgat cagtacgttt cacgatctcc atgccgagga aaagcagatg
     1801 ttagccaaac tccacgaact ggagcagaac cgacctagcg atgtgtacct ctcgtcccgc
     1861 gaccgcctga tcttggactg gcattttgcc aacttggaat ttgctaatgc cacccgacta
     1921 aataacctgt cgttgaagca ctgggatcag gacgatgact tcgagtttat tggccaccac
     1981 acaactgtgc ggaacggtta ttcatgtgtg cctgtagctc ttactgaaaa cctggacatc
     2041 cgtgtcaata gcgccgtcaa ggagataaag tacggcacca aaggtgtgga agtagtggct
     2101 gaaaacttga agacatccaa ttcgcagatg acatacaagg cagaccttgt cgtctgcaca
     2161 cttactctgg gcgtcctcaa agtggcggta gcacataagg agtcacagca gagtaacaca
     2221 gtcaagttcg acccgccatt gccggactgg aaacagcagg ccatcaaaag gctgggattt
     2281 gggaatctca ataaggttgt gctctgcttc gatcgcattt tttgggatcc caacgctaat
     2341 ctcttcggac acgtgggcag cacgacggcg agtagaggag aaatgtttct gttctggagt
     2401 ataagctcat ctccggtgtt gctcgctcta gtcgccggaa tggcagcgaa tctggtggag
     2461 agcgtgacgg atgacatcat aatcgggcgt tgtatgtcgg tgctaaaaaa catcttcggg
     2521 aatacctctg ttccacaacc caaggaaaca gtggtaacgc gttggcgcag cgatccctgg
     2581 gcccgtgggt cgtacagcta cgtatccgtt ggttcctcgg gcagtgacta cgatctgctg
     2641 gcggcgccgg tcattccgcc gtccagtaag gatgcggaag gattgccacg gctattcttc
     2701 gcgggtgagc atacgatacg gaattatccg gccactgtgc atggagcgta cttgagcgga
     2761 ttgcgcgagg cgggacgtat tgcggattac tatctcggct atccagaggg aacaccgccg
     2821 gacattggct actcggtggc tgaggcggcc aatctggtgt ccgtgggaaa tgttgtcaag
     2881 ctgcgcgacc tctcgcccaa tctatctgac tcctccccgt cgtcaaagaa gtcggaggag
     2941 aattcaaact caaacactgc cgactctacg gagctacagt aacaatgtat ttagcgtgat
     3001 ggatttggtc cccagcagtt actcctagag cgtttagttt tgtatcatac aactggggct
     3061 cgctgtttaa aacgaagcta ggccgctgta aatacctaag actattcaac taagcataga
     3121 ccactttcat tcaaccaatt ataaattaag ataaaaagca ataacaccca acaaagcaaa
     3181 tcctcttcag tgtttccttc agatcaaagt aaaccaacct ctgtgcgcct ataattgatc
     3241 aacaaatgca atcatctatc ataactttcc gtaccactta cccgccaatg aggagtatat
     3301 cttttaagta tattatcgcc tataagattg ttttcaataa gtattttgta aattaaattt
     3361 gaaaatagta aattaaattg acgccgatat ttttaattag gttaatttaa tttaagtaca
     3421 aatttcatat tacttccaac ttaaaaacac tttcaatttt tttaatatct tattgttatc
     3481 ttgataaaat acgatgtaga aaaatgtgta cgcaaatcat ggcataaatt gagttttaaa
     3541 atataatgta agctt
//
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