Homo sapiens serine peptidase inhibitor, Kunitz type 2 (SPINT2), trans - Nucleotide

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SPINT2 mutations in the Kunitz domain 2 found in SCSD patients inactivate HAI-2 as prostasin inhibitor via abnormal protein folding and N-glycosylation. [Hum Mol Genet. 2024]
SPINT2 mutations in the Kunitz domain 2 found in SCSD patients inactivate HAI-2 as prostasin inhibitor via abnormal protein folding and N-glycosylation.
Huang N, Wang Q, Bernard RB, Chen CY, Hu JM, Wang JK, Chan KS, Johnson MD, Lin CY. Hum Mol Genet. 2024 Apr 18; 33(9):752-767.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling. [Int J Mol Sci. 2022]
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling.
Kouranti I, Abdel Khalek W, Mazurkiewicz S, Loisel-Ferreira I, Gautreau AM, Pintard L, Jeunemaitre X, Clauser E. Int J Mol Sci. 2022 May 5; 23(9). Epub 2022 May 5.
Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling. [Cell Oncol (Dordr). 2022]
Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling.
Bernhard SV, Seget-Trzensiok K, Kuffer C, Krastev DB, Stautmeister LM, Theis M, Keuper K, Boekenkamp JE, Kschischo M, Buchholz F, et al. Cell Oncol (Dordr). 2022 Feb; 45(1):103-119. Epub 2021 Dec 28.

RefSeq alternative splicing
See the other reference mRNA sequence splice variant for the SPINT2 gene (NM_021102.4).
RefSeq protein product
See the reference protein sequence for kunitz-type protease inhibitor 2 isoform b precursor (NP_001159575.1).

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Protein sequence from Nucleotide coding region
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Nucleotide