Homo sapiens sphingosine kinase 1 (SPHK1), transcript variant 3, mRNA

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Interference with sphingosine kinase-1 reduces the hydrogen peroxide-induced oxidative stress damage in melanocytes through four and a half LIM domains 2. [Gen Physiol Biophys. 2024]
Interference with sphingosine kinase-1 reduces the hydrogen peroxide-induced oxidative stress damage in melanocytes through four and a half LIM domains 2.
Liao KH, Liao KL. Gen Physiol Biophys. 2024 Jul; 43(4):321-333.
SphK1 deficiency ameliorates the development of atherosclerosis by inhibiting the S1P/S1PR3/Rhoa/ROCK pathway. [Cell Signal. 2024]
SphK1 deficiency ameliorates the development of atherosclerosis by inhibiting the S1P/S1PR3/Rhoa/ROCK pathway.
Piao J, Su Z, He J, Zhu T, Fan F, Wang X, Yang Z, Zhan H, Luo D. Cell Signal. 2024 Sep; 121:111252. Epub 2024 Jun 7.
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis. [J Transl Med. 2024]
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Liu XT, Huang Y, Liu D, Jiang YC, Zhao M, Chung LH, Han XD, Zhao Y, Chen J, Coleman P, et al. J Transl Med. 2024 Jan 10; 22(1):43. Epub 2024 Jan 10.

RefSeq alternative splicing
See 5 reference mRNA sequence splice variants for the SPHK1 gene.
RefSeq protein product
See the reference protein sequence for sphingosine kinase 1 isoform 3 (NP_001136073.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
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Annotated Genomic
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OMIM
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Ensembl [Ensembl]
Ensembl
sphingosine kinase 1 [Guide to Pharmacology]
sphingosine kinase 1
Guide to Pharmacology
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Nucleotide