Mus musculus sodium channel, voltage-gated, type VIII, alpha (Scn8a), - Nucleotide

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy. [JCI Insight. 2024]
Parvalbumin interneuron impairment causes synaptic transmission deficits and seizures in SCN8A developmental and epileptic encephalopathy.
Miralles RM, Boscia AR, Kittur S, Hanflink JC, Panchal PS, Yorek MS, Deutsch TCJ, Reever CM, Vundela SR, Wengert ER, et al. JCI Insight. 2024 Oct 22; 9(20). Epub 2024 Oct 22.
Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy. [Neurobiol Dis. 2024]
Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy.
Yu W, Hill SF, Zhu L, Demetriou Y, Reger F, Mattis J, Meisler MH. Neurobiol Dis. 2024 Sep; 199:106591. Epub 2024 Jul 3.
Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6. [Sci Rep. 2024]
Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of Na(V)1.2 and Na(V)1.6.
Arratia LM, Bermudes-Contreras JD, Juarez-Monroy JA, Romero-Macías EA, Luna-Rojas JC, López-Hidalgo M, Vega AV, Zamorano-Carrillo A. Sci Rep. 2024 Mar 21; 14(1):6761. Epub 2024 Mar 21.

RefSeq alternative splicing
See 12 reference mRNA sequence splice variants for the Scn8a gene.
RefSeq protein product
See the reference protein sequence for sodium channel protein type 8 subunit alpha isoform 1 (NP_001070967.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
GEO Profiles
GEO Profile records associated with Nucleotide record

Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
Nav1.6 [Guide to Pharmacology]
Nav1.6
Guide to Pharmacology
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide