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NCBI Reference Sequence: NG_182521.1
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LOCUS NG_182521 260 bp DNA linear CON 17-MAY-2023 DEFINITION Homo sapiens ATAC-STARR-seq lymphoblastoid silent region 20576 (LOC130003075) on chromosome 9. ACCESSION NG_182521 VERSION NG_182521.1 DBLINK BioProject: PRJNA343958 KEYWORDS RefSeq; RefSeqFE. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 260) AUTHORS Hansen TJ and Hodges E. TITLE ATAC-STARR-seq reveals transcription factor-bound activators and silencers across the chromatin accessible human genome JOURNAL Genome Res 32 (8), 1529-1541 (2022) PUBMED 35858748 REMARK Publication Status: Available-Online prior to print COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL807752.10. Summary: This genomic sequence represents an accessible chromatin region that was validated as a silencer based on its ability to repress an origin of replication minimal core promoter by the ATAC-STARR-seq (assay for transposase-accessible chromatin with self-transcribing active regulatory region sequencing) massively parallel reporter assay (MPRA) in GM12878 lymphoblastoid cells. [provided by RefSeq, May 2023]. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-260 AL807752.10 147572-147831 FEATURES Location/Qualifiers source 1..260 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" /chromosome="9" /map="9" misc_feature 101..160 /standard_name="ATAC-STARR-seq lymphoblastoid silent region 20576" /note="Region: biological region" /db_xref="GeneID:130003075" regulatory 101..160 /regulatory_class="silencer" /experiment="EXISTENCE:reporter gene assay evidence [ECO:0000049][PMID:35858748]" /note="silent region_20576" /function="represses an Ori minimal core promoter by ATAC-STARR-seq in GM12878 lymphoblastoid cells {active_cell/tissue: GM12878}" /db_xref="GeneID:130003075" CONTIG join(AL807752.10:147572..147831) //
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