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NCBI Reference Sequence: NG_131924.1
FASTA Graphics
LOCUS NG_131924 519 bp DNA linear CON 08-APR-2023 DEFINITION Homo sapiens NANOG hESC enhancer GRCh37_chr15:81585795-81586313 (LOC127830442) on chromosome 15. ACCESSION NG_131924 REGION: 101..619 VERSION NG_131924.1 DBLINK BioProject: PRJNA343958 KEYWORDS RefSeq; RefSeqFE. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 519) AUTHORS Barakat TS, Halbritter F, Zhang M, Rendeiro AF, Perenthaler E, Bock C and Chambers I. TITLE Functional Dissection of the Enhancer Repertoire in Human Embryonic Stem Cells JOURNAL Cell Stem Cell 23 (2), 276-288 (2018) PUBMED 30033119 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC103858.2. Summary: This genomic region was validated as an active enhancer by the ChIP-STARR-seq massively parallel reporter assay in naive human embryonic stem cells. This enhancer associates with the NANOG transcription factor. [provided by RefSeq, Nov 2022]. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-719 AC103858.2 109023-109741 FEATURES Location/Qualifiers source 1..519 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" /chromosome="15" /map="15" misc_feature 1..519 /standard_name="NANOG hESC enhancer GRCh37_chr15:81585795-81586313" /note="Region: biological region" /db_xref="GeneID:127830442" regulatory 1..519 /regulatory_class="enhancer" /experiment="EXISTENCE:reporter gene assay evidence [ECO:0000049][PMID:30033119]" /note="NANOG hESC enhancer chr15:81585795-81586313 (GRCh37/hg19 assembly coordinates)" /function="activates a minimal SCP1, AML or CMV promoter by ChIP-STARR-seq in naive H9 embryonic stem cells {active_cell/tissue: H9 hESC(naive)}" /db_xref="GeneID:127830442" ORIGIN 1 gcactttggg aggctgagcc gggtggatca tgagctcagg agttcaagac cagcctggcc 61 aagatggtga aaccctgtct ctactaacaa tacaaaaatt agccgggtat ggtggcaggt 121 gcctgtaatc ccagctacgc aggaggctga ggcagggaat tgcttaaacc cgggaggagt 181 ggctccttcc aagggctatt gtgaggatta aaggtaacca cttaaggcaa gtacctgaca 241 gcatctcagg catattagca ttcattgcca tgatctttcc ccatcaggcc ccttaaagcc 301 ctcctttcca ccccttgcat aaaaggcaga ctgactgaca gacagctgct gtgtctagaa 361 ccattttatg cgcaggctaa ccacactgag tactttcatg tacattgtgt caattaaatc 421 ttacaaccac ctgatggtga gagtcccagt tgtgcaaaga gggaactgag aaactcgctc 481 aagttcacat tgctagtggg tcacagttac ccactatgc //
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