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NCBI Reference Sequence: NG_046145.1
FASTA Graphics
LOCUS NG_046145 504 bp DNA linear CON 13-MAR-2023 DEFINITION Homo sapiens nonconserved acetylation island sequence 104 enhancer (LOC106799844) on chromosome X. ACCESSION NG_046145 REGION: 101..604 VERSION NG_046145.1 DBLINK BioProject: PRJNA343958 KEYWORDS RefSeq; RefSeqFE. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 504) AUTHORS Roh TY, Wei G, Farrell CM and Zhao K. TITLE Genome-wide prediction of conserved and nonconserved enhancers by histone acetylation patterns JOURNAL Genome Res 17 (1), 74-81 (2007) PUBMED 17135569 REFERENCE 2 (bases 1 to 504) AUTHORS Roh TY, Cuddapah S and Zhao K. TITLE Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping JOURNAL Genes Dev 19 (5), 542-552 (2005) PUBMED 15706033 COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC112497.4. Summary: This region, which is not conserved between human and mouse at the sequence level, can function as an enhancer in human Jurkat T cells. Its chromatin structure represents a histone acetylation island in human T cells based on the diacetylation of histone H3 at lysines 9 and 14. [provided by RefSeq, Nov 2015]. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-704 AC112497.4 94480-95183 c FEATURES Location/Qualifiers source 1..504 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" /chromosome="X" /map="Xp22.2" misc_feature 1..504 /standard_name="nonconserved acetylation island sequence 104 enhancer" /note="Region: biological region" /db_xref="GeneID:106799844" regulatory 1..504 /regulatory_class="enhancer" /experiment="EXISTENCE:reporter gene assay evidence [ECO:0000049][PMID:17135569]" /note="nonconserved acetylation island sequence 104" /function="activates a minimal heat-shock promoter by reporter assays in Jurkat T cells {active_cell/tissue: Jurkat}" /db_xref="GeneID:106799844" ORIGIN 1 gaggagtgtg cttactccat gtatctccct agcatttaaa gtccgctgac tttaaatggg 61 ctggaaggaa cacggttcca gtttatctcc atatcgggtt aaaggacatg aaacctagct 121 agaaggaaca ttgctccacc actggcccat cagttctgtt tcctactcgg tttttgctta 181 acgagttgtg gtgtttagag ttgggagata catggagaaa gtcacttttt aggagaggat 241 cagagatccg caggctcatt tcactctata aatgccgcgg acatctggtt ccaggacctg 301 gacagtcctc tctggagact ggtgggcccc tccaacacct ccgtggcttc ccgggatcaa 361 gtatcgcacc taaaaggagc gcagagagcg tgcaactggc gggagaggcg tgaccagagt 421 ggaaccaaaa gtgggtggcc tgggaaccta acgcgtgacc agaagtgaag gtaggtaagt 481 gcgcatgcgc aggatgcgag tggc //
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