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NCBI Reference Sequence: NC_060934.1
FASTA Graphics
LOCUS NC_060934 4440 bp DNA linear CON 26-AUG-2024 DEFINITION Homo sapiens isolate CHM13 chromosome 10, alternate assembly T2T-CHM13v2.0. ACCESSION NC_060934 REGION: 87903926..87908365 VERSION NC_060934.1 DBLINK BioProject: PRJNA807723 BioSample: SAMN03255769 Assembly: GCF_009914755.1 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. COMMENT REFSEQ INFORMATION: The reference sequence is identical to CP068268.2. Assembly name: T2T-CHM13v2.0 The genomic sequence for this RefSeq record is from the whole-genome assembly released by the T2T Consortium on 2022/01/24. ##Genome-Assembly-Data-START## Assembly Date :: 23-APR-2021 Assembly Method :: T2T assembly pipeline + rDNA (see manuscript for details) v. 04/23/2021 Assembly Name :: T2T-CHM13v2.0 Genome Representation :: Full Expected Final Version :: No Genome Coverage :: 30.0x Sequencing Technology :: PacBio Sequel II HiFi; Oxford Nanopore MinION; Illumina NovaSeq ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_009914755.1-RS_2024_08 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; RefSeqFE; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 08/23/2024 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..4440 /organism="Homo sapiens" /mol_type="genomic DNA" /isolate="CHM13" /db_xref="taxon:9606" /chromosome="10" /sex="female" /cell_line="CHM13htert" /tissue_type="hydatidiform mole" /note="haploid cell line" misc_feature <1..20 /standard_name="H3K4me1 hESC enhancer GRCh37_chr10:88779570-88780070" /note="Region: biological region; Derived by automated computational analysis using gene prediction method: RefSeqFE." /db_xref="GeneID:127818708" regulatory <1..20 /regulatory_class="enhancer" /experiment="EXISTENCE:reporter gene assay evidence [ECO:0000049][PMID:30033119]" /note="H3K4me1 hESC enhancer chr10:88779570-88780070 (GRCh37/hg19 assembly coordinates)" /function="activates a minimal SCP1, AML or CMV promoter by ChIP-STARR-seq in naive H9 embryonic stem cells {active_cell/tissue: H9 hESC(naive)}" /db_xref="GeneID:127818708" gene 1..4440 /gene="FAM25A" /gene_synonym="bA96C23.5" /note="family with sequence similarity 25 member A; Derived by automated computational analysis using gene prediction method: BestRefSeq." /db_xref="GeneID:643161" /db_xref="HGNC:HGNC:23436" mRNA join(1..104,2021..2083,4251..4440) /gene="FAM25A" /gene_synonym="bA96C23.5" /product="family with sequence similarity 25 member A" /inference="similar to RNA sequence, mRNA (same species):RefSeq:NM_001146157.3" /exception="annotated by transcript or proteomic data" /note="The RefSeq transcript has 1 substitution compared to this genomic sequence; Derived by automated computational analysis using gene prediction method: BestRefSeq." /transcript_id="NM_001146157.3" /db_xref="GeneID:643161" /db_xref="HGNC:HGNC:23436" misc_feature 21..521 /standard_name="H3K4me1 hESC enhancer GRCh37_chr10:88780071-88780571" /note="Region: biological region; Derived by automated computational analysis using gene prediction method: RefSeqFE." /db_xref="GeneID:127818709" regulatory 21..521 /regulatory_class="enhancer" /experiment="EXISTENCE:reporter gene assay evidence [ECO:0000049][PMID:30033119]" /note="H3K4me1 hESC enhancer chr10:88780071-88780571 (GRCh37/hg19 assembly coordinates)" /function="activates a minimal SCP1, AML or CMV promoter by ChIP-STARR-seq in naive H9 embryonic stem cells {active_cell/tissue: H9 hESC(naive)}" /db_xref="GeneID:127818709" CDS join(32..104,2021..2083,4251..4384) /gene="FAM25A" /gene_synonym="bA96C23.5" /note="Derived by automated computational analysis using gene prediction method: BestRefSeq." /codon_start=1 /product="protein FAM25A" /protein_id="NP_001139629.1" /db_xref="GeneID:643161" /db_xref="HGNC:HGNC:23436" /translation="MLGGLGKLAAEGLAHRTEKATEGAIHAVEEVVKEVVGHAKETGE KAIAEAIKKAQESGDKKMKEITETVTNTVTNAITHAAESLDKLGQ" misc_feature 4223..>4440 /standard_name="OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:88784270-88785122" /note="Region: biological region; Derived by automated computational analysis using gene prediction method: RefSeqFE." /db_xref="GeneID:127818710" regulatory 4223..>4440 /regulatory_class="enhancer" /experiment="EXISTENCE:reporter gene assay evidence [ECO:0000049][PMID:30033119]" /note="OCT4-NANOG-H3K27ac hESC enhancer chr10:88784270-88785122 (GRCh37/hg19 assembly coordinates)" /function="activates a minimal SCP1, AML or CMV promoter by ChIP-STARR-seq in naive H9 embryonic stem cells {active_cell/tissue: H9 hESC(naive)}" /db_xref="GeneID:127818710" ORIGIN 1 atcctagttc accactgtct gctgccacac gatgctggga ggcctgggga agctggctgc 61 cgaaggcctg gcccaccgca ccgagaaggc caccgaggga gccagtgagg acctggggct 121 cctttctacc tgggctgggg ggatctgggg cagactgggt ctgtgggagg cggatctaag 181 taggcaggtg aggacctggg aggaggcctt ggcccctcag gaaccctggt cccctgctct 241 accaagtcag cacggagttg aggggtgcag acctggggag gtctcctggg ggcagggcat 301 gagtcctggt gctgggtgaa cactggcagc ttggaccctt ccctctggaa atctggggag 361 cctttcttgt caaaacagcc tattctgaat aacctatgca ggaaaaggaa gacggatttt 421 tatttttacc ataactttaa agcttcaaag atttctaaac aagtcaccaa gtctgttcaa 481 agtcaaaaag ggcattttca atttcatcca agtcccctga agcatgttta tttttatttt 541 tatttgtatt tgaaatggag tcttgctctg gcacccaggc tggagtgtag tggtgcgatc 601 tcggctcact gtaacctctg cctcctgggt tcaaagtgat tctcatgcct tagcctcctg 661 agtgtctggg attacaggca cccaccacca tgcccaacta atttttatat ttttagcaga 721 gacagggttt cgccatgttg gccaggctgg tctcaaactc ctgacctcaa gtgatccatt 781 cctcttggcc tcccaaagtg ctgggattgc aggcgtgaac caccgcacct ggtcccgaag 841 tgtatgttgt attcagaggt cagcagctat gtgtggggag gcccagccag gagccactca 901 tgggtcatcg tgtgaaaaac agtcttgcct gagtttgtgt cctctttcta aatggcagca 961 gacgcgtatt ttgtttttga ctctgcagct ggtgtggacc acctgcttta acctttcact 1021 agcctctgag ttttgtatga ttcctgttgg gagaaaagct gagtattggg agagaagctg 1081 aggcagggct tgctagattg gctggctcct tgcttctagc actcccattc tctcaagtag 1141 ccgtatgttt ctcattcact tgatacaccg tttcctttca accgccacat cctcaccacc 1201 tgtttctttg ttagatcacc aataaatagc atgggttccc agaactccgg gccttcgcag 1261 cctccacact cgcgatggcg ccccgctccc attttctctc tcaaactgtc tctttctcat 1321 tcctttgact cctctggact tgccgccccc gcgacctggt gttgggtctc atcaccccaa 1381 cagattccca ttctaaagat gagggaacca agaggtggaa ggtagagtta gaataagaac 1441 catttcttct gactctgaaa tccttcagtt ctagcatgct accacctaca ctttaaaaaa 1501 ctctgaagta ggcagagaat tcccttttgt tggaggaatt gctttgagag acctggtttt 1561 actggatgag gctttggaaa ccaacctgag gcaggcgcta gcacatcctg agaggggtgt 1621 gacctggcac agaggcccag cctgggcttc atgtctcagc tggcaagatg gcctgctcat 1681 tgccattcca ggccgggcag ggccaagggg cttcagggac ccatgccctc atggggctca 1741 ctgagctcgt ctcccggcag ccaaggccct ggcgtctccg aaggaagcca gctgtggggg 1801 aaggtccttc tcatgagcca gtctgtcctg gctgggggtg gcatcccaga gccccatcta 1861 ggatgtccag ggatgtatag gtccattgtg aggataagcc agcactgagc cctcaccctg 1921 gactgggagg gcagtgggcc tgctctgagc cctcaccctg gactgggagg gcagcggctc 1981 tgctctgagc cctcaccctg gacttgtctc ctctgttcag ttcatgccgt ggaagaagtg 2041 gtgaaggagg tggtgggaca tgccaaggag actggagaga aaggtacagc tggctgaggt 2101 cgggcaggga aggagggagg gagcaaggga agctaggtgc tgggccaacc tgttctttga 2161 ctaaccaggt caaactctgc ccccaatgtt gcagcctttc agagcctctt ggctggggca 2221 gttatctatg ctcatcagag gccacagact gtactgcgtt agggcactgt ctagatggtt 2281 ctgtctgtgg aataagaaga caaagtcaca caagactatg tgacagcaca ctgggacaaa 2341 acatttaaca tggcagggcg cggtggctca cgcctgtaat cccagccctt tgggaggctg 2401 aggagggtgg atcacgaggt caggagattg agaccatcct ggctaacacg gtgaaacccc 2461 atctctacta aaaatacata aaaattagcc gggcatggtg gtgggtgcct atagtcccag 2521 ctacttggga ggctgaggca ggagaatggt gtgtacctgg gaggcagagc ttgcagtgag 2581 cctagatcat gccactgcac tccagcctgg gctacagagt gagactcggt ctcaaaaaaa 2641 aaaaaagaaa aaaaaaattg ctgggtgtgg tggctcacgc ctgtgatccc agcactttgg 2701 gagcctgagg tgggcggatc acgaggtcag gagatccaga ccacggtgaa accccatctc 2761 tactaaaaat acaaaaaatt agctgggcac ggtggcgggt gcctgtagtc ccagctactc 2821 gggaggctga ggcaggagaa tggcgtgaac ccggaaggcg gagcttgcag tgagccgaga 2881 tcgtgccact gcactccagc ctgggcgaca gtgtgatact ccgtctcaaa aaaaaaaaaa 2941 aatttaacat gtaaaattct atgttaaatg ttaaattgat gtgtgtgagc tatgagtaga 3001 actatgtaca aagcatatgt atatctcatt ccttttcaac aaaatagatt ccaggtagat 3061 gaaggactta aatttacata aatgaattta ttaacttact aggagataac catcttagct 3121 caggctgcta ttataaaata ccataggcca ggtgcagtgg ctcacgcctg taatcctagc 3181 ccttcgggag gccaaggtgg gtgggccacc tgaggtcagg agttcaagac cagcctgacc 3241 aatatggtga aaccccgttg ctactaaaaa tacgaaaacc agctgggcgt ggtggcacat 3301 gcctgtaatc ccagctactc aggagtctga ggcaggatac tcccttgaac ctgggaggcg 3361 gaggttgcag tgagctgaga ttgcaccact gcaccccagc cttggtgaca gagcaagact 3421 ctgtctcaaa aacaaaaaca aaccataaac tgggcgactt agaaacaaca gaaatttatt 3481 tctcacactc ctggaggatg ggaagtccaa gatcaaggaa ggcactggca gatttggcat 3541 ctggtgaggg agtctttctg gttcgtggat gggcccagct ctgtcctcac atggtggaag 3601 gagctagctc tctgtggtct cttttatgtg ggtgctaatt tcaacctccc aaaggcccca 3661 cctcttaata tcattacatt aagactgagg atttcaacgt atgagttttg agggggaaga 3721 catcataaac atttagacat agtaataaca taaaagactt tggcctaatc ttggagaggg 3781 gagaatcttt agaaccatga caaaaaaatc agcgccataa aggaaatatt aagtaaattt 3841 gacaatccaa aactgaaatt ttctatagcc aaaaaaaaaa aactataaac caagccaaaa 3901 gaaaaattac acactgatga aaaatatttg tcataaaaat gataatccaa tataacaacc 3961 caatataaaa atggtcaaaa gacataagca ggcattttcc agaaaaaagg ataagcaggc 4021 aatgtaccca tgagtagatg ctcagtctca ctcacagttg aagaaatgca agttgttggg 4081 gaaattaaaa ccaaattcaa attcattctg cagtaatcct gctgcccttg gtcccatcgg 4141 gccactccag agactaatcc attaagatgg ccacatccca caggccactc aaggggacac 4201 aagttcagcg ggtggatcac taggacattc ttcctctttc tttccaacag ccattgctga 4261 agccataaag aaagcccaag agtcagggga caaaaagatg aaggaaatca ctgagacagt 4321 gaccaacaca gtcacaaatg ccatcaccca tgcagcagag agtctggaca aacttggaca 4381 gtgagtgcac ctgctaccac ggcccttccc cagtctcaat aaaaagccat gacatgtgta //
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