U.S. flag

An official website of the United States government

Pseudomonas aeruginosa PAO1, complete genome

NCBI Reference Sequence: NC_002516.2

FASTA Graphics 

LOCUS       NC_002516                903 bp    DNA     linear   CON 24-JAN-2019
DEFINITION  Pseudomonas aeruginosa PAO1, complete genome.
ACCESSION   NC_002516 REGION: 1373945..1374847
VERSION     NC_002516.2
DBLINK      BioProject: PRJNA57945
            Assembly: GCF_000006765.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa PAO1
  ORGANISM  Pseudomonas aeruginosa PAO1
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (bases 1 to 903)
  AUTHORS   Winsor,G.L., Van Rossum,T., Lo,R., Khaira,B., Whiteside,M.D.,
            Hancock,R.E. and Brinkman,F.S.
  TITLE     Pseudomonas Genome Database: facilitating user-friendly,
            comprehensive comparisons of microbial genomes
  JOURNAL   Nucleic acids Res. 37 (DATABASE ISSUE), D483-D488 (2009)
   PUBMED   18978025
REFERENCE   2  (bases 1 to 903)
  AUTHORS   Cirz,R.T., O'Neill,B.M., Hammond,J.A., Head,S.R. and Romesberg,F.E.
  TITLE     Defining the Pseudomonas aeruginosa SOS response and its role in
            the global response to the antibiotic ciprofloxacin
  JOURNAL   J. Bacteriol. 188 (20), 7101-7110 (2006)
   PUBMED   17015649
REFERENCE   3  (bases 1 to 903)
  AUTHORS   Palmer,K.L., Mashburn,L.M., Singh,P.K. and Whiteley,M.
  TITLE     Cystic fibrosis sputum supports growth and cues key aspects of
            Pseudomonas aeruginosa physiology
  JOURNAL   J. Bacteriol. 187 (15), 5267-5277 (2005)
   PUBMED   16030221
REFERENCE   4  (bases 1 to 903)
  AUTHORS   Salunkhe,P., Smart,C.H., Morgan,J.A., Panagea,S., Walshaw,M.J.,
            Hart,C.A., Geffers,R., Tummler,B. and Winstanley,C.
  TITLE     A cystic fibrosis epidemic strain of Pseudomonas aeruginosa
            displays enhanced virulence and antimicrobial resistance
  JOURNAL   J. Bacteriol. 187 (14), 4908-4920 (2005)
   PUBMED   15995206
REFERENCE   5  (bases 1 to 903)
  AUTHORS   Filiatrault,M.J., Wagner,V.E., Bushnell,D., Haidaris,C.G.,
            Iglewski,B.H. and Passador,L.
  TITLE     Effect of anaerobiosis and nitrate on gene expression in
            Pseudomonas aeruginosa
  JOURNAL   Infect. Immun. 73 (6), 3764-3772 (2005)
   PUBMED   15908409
REFERENCE   6  (bases 1 to 903)
  AUTHORS   Rasmussen,T.B., Bjarnsholt,T., Skindersoe,M.E., Hentzer,M.,
            Kristoffersen,P., Kote,M., Nielsen,J., Eberl,L. and Givskov,M.
  TITLE     Screening for quorum-sensing inhibitors (QSI) by use of a novel
            genetic system, the QSI selector
  JOURNAL   J. Bacteriol. 187 (5), 1799-1814 (2005)
   PUBMED   15716452
REFERENCE   7  (bases 1 to 903)
  AUTHORS   Winsor,G.L., Lo,R., Sui,S.J., Ung,K.S., Huang,S., Cheng,D.,
            Ching,W.K., Hancock,R.E. and Brinkman,F.S.
  TITLE     Pseudomonas aeruginosa Genome Database and PseudoCap: facilitating
            community-based, continually updated, genome annotation
  JOURNAL   Nucleic acids Res. 33 (DATABASE ISSUE), D338-D343 (2005)
   PUBMED   15608211
REFERENCE   8  (bases 1 to 903)
  AUTHORS   Wagner,V.E., Bushnell,D., Passador,L., Brooks,A.I. and
            Iglewski,B.H.
  TITLE     Microarray analysis of Pseudomonas aeruginosa quorum-sensing
            regulons: effects of growth phase and environment
  JOURNAL   J. Bacteriol. 185 (7), 2080-2095 (2003)
   PUBMED   12644477
REFERENCE   9  (bases 1 to 903)
  AUTHORS   Schuster,M., Lostroh,C.P., Ogi,T. and Greenberg,E.P.
  TITLE     Identification, timing, and signal specificity of Pseudomonas
            aeruginosa quorum-controlled genes: a transcriptome analysis
  JOURNAL   J. Bacteriol. 185 (7), 2066-2079 (2003)
   PUBMED   12644476
REFERENCE   10 (bases 1 to 903)
  AUTHORS   Stover,C.K., Pham,X.Q., Erwin,A.L., Mizoguchi,S.D., Warrener,P.,
            Hickey,M.J., Brinkman,F.S., Hufnagle,W.O., Kowalik,D.J., Lagrou,M.,
            Garber,R.L., Goltry,L., Tolentino,E., Westbrock-Wadman,S., Yuan,Y.,
            Brody,L.L., Coulter,S.N., Folger,K.R., Kas,A., Larbig,K., Lim,R.,
            Smith,K., Spencer,D., Wong,G.K., Wu,Z., Paulsen,I.T., Reizer,J.,
            Saier,M.H., Hancock,R.E., Lory,S. and Olson,M.V.
  TITLE     Complete genome sequence of Pseudomonas aeruginosa PA01, an
            opportunistic pathogen
  JOURNAL   Nature 406 (6799), 959-964 (2000)
   PUBMED   10984043
REFERENCE   11 (bases 1 to 903)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-OCT-2010) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   12 (bases 1 to 903)
  AUTHORS   Winsor,G.L., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (08-SEP-2010) Department of Molecular Biology and
            Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
            British Columbia V5A 1S6, Canada
  REMARK    protein update by submitter
REFERENCE   13 (bases 1 to 903)
  AUTHORS   Winsor,G.L., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (02-OCT-2008) Department of Molecular Biology and
            Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
            British Columbia V5A 1S6, Canada
  REMARK    protein update by submitter
REFERENCE   14 (bases 1 to 903)
  AUTHORS   Winsor,G.L., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUL-2006) Department of Molecular Biology and
            Biochemisry, Simon Fraser University, 8888 University Dr., Burnaby,
            British Columbia V5A 1S6, Canada
  REMARK    Sequence update by submitter
REFERENCE   15 (bases 1 to 903)
  AUTHORS   Ung,K.S., Hancock,R.E. and Brinkman,F.S.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (04-FEB-2003) Department of Molecular Biology and
            Biochemistry, Simon Fraser University, 8888 University Dr.,
            Burnaby, British Columbia V5A 1S6, Canada
REFERENCE   16 (bases 1 to 903)
  AUTHORS   Stover,C.K., Pham,X.-Q.T., Erwin,A.L., Mizoguchi,S.D., Warrener,P.,
            Hickey,M.J., Brinkman,F.S.L., Hufnagle,W.O., Kowalik,D.J.,
            Lagrou,M., Garber,R.L., Goltry,L., Tolentino,E.,
            Westbrock-Wadman,S., Yuan,Y., Brody,L.L., Coulter,S.N.,
            Folger,K.R., Kas,A., Larbig,K., Lim,R.M., Smith,K.A., Spencer,D.H.,
            Wong,G.K.-S., Wu,Z., Paulsen,I.T., Reizer,J., Saier,M.H.,
            Hancock,R.E.W., Lory,S. and Olson,M.V.
  CONSRTM   Pseudomonas aeruginosa Community Annotation Project (PseudoCap)
  TITLE     Direct Submission
  JOURNAL   Submitted (16-MAY-2000) Department of Medicine and Genetics,
            University of Washington Genome Center, University Of Washington,
            Box 352145, Seattle, WA 98195, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence is identical to AE004091.
            
            On Jul 24, 2006 this sequence version replaced NC_002516.1.
            RefSeq Category: Reference Genome
                        FGS: First Genome sequenced
                        MOD: Model Organism
                        UPR: UniProt Genome
            -----------------------------------------------------------------
            This represents the Sept 08, 2010 version of the continually
            updated, reviewed, Pseudomonas aeruginosa PAO1 genome annotation
            from PseudoCap (see http://www.pseudomonas.com for the latest
            updates and links to alternate annotations). This update includes
            updated base pair coordinates and new features. PseudoCap is
            coordinated by Fiona S.L. Brinkman (Simon Fraser University,
            Canada) and Robert E.W. Hancock (University of British Columbia,
            Canada) with database development by Geoff Winsor (Simon Fraser
            University). We welcome submission through
            www.pseudomonas.com of any proposed changes.
            'protein name confidence' is used to rate our confidence of the
            accuracy of the protein name.
            class 1: Function experimentally demonstrated in P. aeruginosa.
            class 2: Function of highly similar gene experimentally
            demonstrated in another organism (and gene context consistent in
            terms of pathways its involved in, if known).
            class 3: Function proposed based on presence of conserved amino
            acid motif, structural feature or limited sequence similarity to an
            experimentally studied gene.
            class 4: Homologs of previously reported genes of unknown function,
            or no similarity to any previously reported sequences.
            ------------------------------------------------------------------.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..903
                     /organism="Pseudomonas aeruginosa PAO1"
                     /mol_type="genomic DNA"
                     /strain="PAO1"
                     /db_xref="taxon:208964"
     gene            1..903
                     /locus_tag="PA1265"
                     /db_xref="GeneID:881343"
     CDS             1..903
                     /locus_tag="PA1265"
                     /note="'Product name confidence: class 4 (Homologs of
                     previously reported genes of unknown function, or no
                     similarity to any previously reported sequences)'"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_249956.1"
                     /db_xref="GeneID:881343"
                     /translation="MRATTCTPRAMPGATRLLAVQLGMVLAWSSGFVGYRYAMEQAPV
                     FLTSFWRFAVCLALLLPFAWAGLRRLSARQWRRQALIGALAYAGYIAPIAKAIELGVS
                     PGVAALMADLLPLLVALLALVLPGQRTRPGQWPGIALGVAGVLWAGHAALALGRAPGW
                     AYGLPLLGMLALALATLLQKRWDDAPGSLAVVLFVQIGAALPAFAGLALAEGSLRPPL
                     SGGFLFGLAWLVLLPTFGGYGLYWLGLRHLSAQGGSAALYLSPALTLLWAHWMFAEPL
                     TPMLLGGLLLSLAGLGWLYRAERR"
     gene            complement(900..>903)
                     /locus_tag="PA1266"
                     /db_xref="GeneID:881372"
     CDS             complement(900..>903)
                     /locus_tag="PA1266"
                     /note="'Product name confidence: class 3 (Function
                     proposed based on presence of conserved amino acid motif,
                     structural feature or limited sequence similarity to an
                     experimentally studied gene)'"
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_249957.1"
                     /db_xref="GeneID:881372"
                     /translation="MSADYDLLIVGAGPAGLAAALAAAPSGARIALVDDNPAAGGQIW
                     RDGPRASLPPRAHQMRQRLAGQANVEHFPATRVVACGPGRRLLLEDPQRGWQVGYRRL
                     VLCTGARELLLPFPGWTLPGVTGAGGLQALAKGGLPLAGQRLVVAGSGPLLLASAASA
                     SQCGARLLRVAEQAPARTLAAFAVRLPRWPGKLWQAAGLFARSYRADSYVLAALGEER
                     LEAVRLREGGRVREIACERLACGFGLVPNVQLGQALGYRLDGPALAVDEWQAGSLPDH
                     YAAGECTGFGGSELALVEGAIAGHAAVDERDAARRLWPRRRRWQGFADTLARHFALRA
                     ELRQLAEADTLVCRCEDVPLAALAGHAGWTEAKLHSRCGMGACQGRICGSAAQFLFGW
                     TPPAPRPPFSPARLETLARWQGDAG"
ORIGIN      
        1 atgcgcgcga ccacctgcac cccgcgagcg atgcccgggg cgacccgcct gctggccgtg
       61 caactgggca tggtactggc ctggagttcc ggcttcgtcg gctaccgcta tgccatggaa
      121 caggcgccgg tgttcctcac cagcttctgg cgcttcgccg tttgcctggc gctgctgctg
      181 cccttcgcct gggccgggct gcgccggttg tcggcgcgcc agtggcggcg ccaggcgctg
      241 atcggggcgt tggcctacgc gggctacatc gcgccgatcg ccaaggccat cgaactcggc
      301 gtctcgccgg gcgtggcggc gctgatggcc gacctgttgc cgctgctggt ggccttgctg
      361 gcgctggtcc tgccggggca gcgaacgcgg ccggggcagt ggccggggat cgccctgggc
      421 gtcgccgggg tgctctgggc cgggcatgcg gcgctggcgc tggggcgggc gccgggctgg
      481 gcctacggcc tgccgctgct gggcatgctg gcgctggccc tggccaccct gttgcagaag
      541 cgctgggacg atgcgccggg atcgctggcc gtggtgctgt tcgtgcagat cggcgccgcg
      601 ctgccggcgt tcgccggcct ggcgctggcg gagggtagcc tgcggccgcc gctgtccggc
      661 ggattcctgt tcgggctcgc ctggctggtg ctgctgccca ccttcggcgg ctacggcctg
      721 tactggctgg gcctgcgcca tctttccgca cagggtggca gcgcggcgct gtacctgagc
      781 ccggcgctga ccctgctatg ggcgcactgg atgttcgccg agccgctgac acccatgctg
      841 ctgggtggtc tgctgctgtc gctggccggc ctcggctggc tgtatcgcgc cgagcgtcgc
      901 tag
//
Feature
Display: FASTA GenBank Help
Details

Supplemental Content

Change region shown



Customize view

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
External link. Please review our privacy policy.