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Rat pancreatic cationic trypsinogen mRNA, comlete cds

GenBank: M16624.1

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LOCUS       RATPTRY                  821 bp    mRNA    linear   ROD 27-APR-1993
DEFINITION  Rat pancreatic cationic trypsinogen mRNA, comlete cds.
ACCESSION   M16624
VERSION     M16624.1
KEYWORDS    trypsin; trypsinogen.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Fletcher,T.S., Alhadeff,M., Craik,C.S. and Largman,C.
  TITLE     Isolation and characterization of a cDNA encoding rat cationic
            trypsinogen
  JOURNAL   Biochemistry 26 (11), 3081-3086 (1987)
   PUBMED   3607011
COMMENT     Original source text: Rat pancreas, cDNA to mRNA.
            Draft entry and computer-readable copy of sequence [1] kindly
            provided by T.S.Fletcher, 05-AUG-1987.
            An activation peptide is located at positions 46 to 70. It contains
            5 aspartic acid residues in contrast to the 4 reported for all
            other trypsinogen activation peptides.
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
     mRNA            1..821
                     /product="trypsinogen mRNA"
     CDS             1..744
                     /note="trypsinogen (EC 3.4.21.4)"
                     /codon_start=1
                     /protein_id="AAA41985.1"
                     /translation="MKALIFLAFLGAAVALPLDDDDDKIVGGYTCQKNSLPYQVSLNA
                     GYHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVVEGGEQFIDAAKIIRHPSYNA
                     NTFDNDIMLIKLNSPATLNSRVSTVSLPRSCGSSGTKCLVSGWGNTLSSGTNYPSLLQ
                     CLDAPVLSDSSCKSSYPGKITSNMFCLGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG
                     YGCAQKGKPGVYTKVCNYVNWIQQTVAAN"
     sig_peptide     1..45
                     /note="trypsinogen signal peptide"
     mat_peptide     70..741
                     /product="trypsin mature peptide"
ORIGIN      Unreported.
        1 atgaaggcct taattttcct tgctttcctt ggagctgctg ttgctctccc tctggatgat
       61 gatgatgaca agattgttgg aggctacacc tgccagaaga attctctccc ataccaggtg
      121 tctctgaatg ctggctacca tttttgtgga ggctccctca tcaattccca gtgggttgtt
      181 tcagccgctc actgctacaa atcccgaatt caggtgcgcc tgggagaaca caacattgat
      241 gtcgttgagg gtggtgagca attcattgat gcagctaaaa tcatccgcca ccccagttat
      301 aatgcaaaca cctttgacaa tgatattatg ttgattaagc tgaattcacc tgccaccctc
      361 aattctcgag tgtccactgt ctctctgcca agatcttgtg gatcatctgg tactaagtgc
      421 cttgtgtctg gctggggcaa caccctgagc tctggcacga actacccttc actgcttcag
      481 tgtcttgatg cccctgtcct ctctgacagt tcttgcaaaa gttcttaccc aggcaagatc
      541 actagcaaca tgttctgtct gggctttctg gagggcggaa aggactcctg ccagggtgac
      601 tctggtggcc ctgtagtctg caatggccag ctccagggtg ttgtttcctg gggttatggc
      661 tgtgctcaga aaggaaaacc tggtgtctat accaaggtat gcaactacgt gaactggatt
      721 cagcagaccg tcgctgccaa ctaaaacgcc tttatgtctt tatactttgt agtcaaatcc
      781 accttctttg tatgccccaa gtcattctca caagaaaaac a
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the Prss3b gene (NM_173127.1).

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