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GenBank: J03798.1
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LOCUS HUMSNRNPD 1633 bp mRNA linear PRI 03-AUG-1993 DEFINITION Human autoantigen small nuclear ribonucleoprotein Sm-D mRNA, complete cds. ACCESSION J03798 VERSION J03798.1 KEYWORDS autoantigen; ribonucleoprotein. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1633) AUTHORS Rokeach,L.A., Haselby,J.A. and Hoch,S.O. TITLE Molecular cloning of a cDNA encoding the human Sm-D autoantigen JOURNAL Proc. Natl. Acad. Sci. U.S.A. 85 (13), 4832-4836 (1988) PUBMED 3260384 COMMENT Original source text: Human B-lymphocyte, cDNA to mRNA, clone D45-2. Draft entry and computer-readable sequence [1] kindly submitted by L.Rokeach 20-JUL-1988. The Sm-D protein coded by cDNA D45-2, being a snRNP, is evidently involved in the mRNA splicing of highter eukaryotes; in the autoimmune disease systemic lupus erythematosus, antinuclear antibodies are developed with Sm specificity. FEATURES Location/Qualifiers source 1..1633 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" regulatory 143..149 /regulatory_class="ribosome_binding_site" /note="ribosome binding site" CDS 151..510 /note="small nuclear riboprotein Sm-D" /codon_start=1 /protein_id="AAA36620.1" /translation="MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVK MTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGR GRGRGRGRGRGRGGPRR" ORIGIN 1 bp upstream of EcoRI site. 1 gaattccccc ccccccccca gtgctccgcg cgctcttgac gtccggagcc cctggagtag 61 gcgcttccgg ccattcatac tgcagtcggt cagtgttcgg ttgaaggatt ctgtgtgctg 121 tcggacccag agggtgacgg cgccgctagg atgaagctcg tgagattttt gatgaaattg 181 agtcatgaaa ctgtaaccat tgaattgaag aacggaacac aggtccatgg aacaatcaca 241 ggtgtggatg tcagcatgaa tacacatctt aaagctgtga aaatgaccct gaagaacaga 301 gaacctgtac agctggaaac gctgagtatt cgaggaaata acattcggta ttttattcta 361 ccagacagtt tacctctgga tacactactt gtggatgttg aacctaaggt gaaatctaag 421 aaaagggaag ctgttgcagg aagaggcaga ggaagaggaa gaggaagagg acgtggccgt 481 ggcagaggaa gagggggtcc taggcgataa tgtctctcaa gatttcaaag tcatatgaga 541 tttgggatat tttttgtaca ggttgtgttt gtttatgtca gtttttaata aacataaatg 601 tgggacagag ctgtctattt agtatatcaa agttttagta gtttcctcca cattcacgaa 661 attaccacag tgagagctaa gcatttctac tgggcagttt catttttagt tgatcaggtt 721 ttaagttttt gaactaaaat ttttcttttt ctttttatga tgaataaggt taaaataaaa 781 gccttagaca aattaaattt ggcagagttt aattgagcaa aggacaattc acaaatcagg 841 tagcccctga accataatag gctcagaggc ttcagcccag ctgcatagtt gaagatttat 901 ggacagaagg aaagtgatgt atggaaaatg gaagtgagat acagcaacag ccggattagt 961 tacagttcag cgtttgcctt atttgaatat ggtttgaaca gttcgctgtc tttggttggc 1021 tgaaacttag tgattgccac aagagtaggg taccgtctgt ttacacgtcc agttaggcta 1081 cagttctatg tactgagaaa cctttaagct gaacttgaga tatgtaaaga gactttaggc 1141 taaacttaac aatatatata ggaatatatc ccttctactt cacatgcact gaatatgcat 1201 tttattgctt tactcttcat tctgtggcac ctacccacag gggaagtaag aagtttgttt 1261 tggtatttcg gaaactaaag tccttatggg atggggtcta gaattgattc tcctttcctg 1321 agttttactc cacggagtct taggtacctg gtaaaaagtt gtcttctaaa ttaagggtca 1381 ttgctttgtt gtctagctgc taatgtctta cttttgtttc ttttgctttt taatcagttc 1441 ttaataggat atagttttat gttttccaag ttataacttg gagttaatgg tcactagatt 1501 atcagttatg agcagtgtta aaatctccta ttaatgtgta atgtacctgt cagtgcctcc 1561 tttattaagg ggttctttga gaataaaaga gaaaagacct actttatttg acagcaaaaa 1621 aaaaaaggaa ttc //
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