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Human autoantigen small nuclear ribonucleoprotein Sm-D mRNA, complete cds

GenBank: J03798.1

FASTA Graphics 

LOCUS       HUMSNRNPD               1633 bp    mRNA    linear   PRI 03-AUG-1993
DEFINITION  Human autoantigen small nuclear ribonucleoprotein Sm-D mRNA,
            complete cds.
ACCESSION   J03798
VERSION     J03798.1
KEYWORDS    autoantigen; ribonucleoprotein.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1633)
  AUTHORS   Rokeach,L.A., Haselby,J.A. and Hoch,S.O.
  TITLE     Molecular cloning of a cDNA encoding the human Sm-D autoantigen
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 85 (13), 4832-4836 (1988)
   PUBMED   3260384
COMMENT     Original source text: Human B-lymphocyte, cDNA to mRNA, clone
            D45-2.
            Draft entry and computer-readable sequence [1] kindly submitted by
            L.Rokeach 20-JUL-1988.
            The Sm-D protein coded by cDNA D45-2, being a snRNP, is evidently
            involved in the mRNA splicing of highter eukaryotes; in the
            autoimmune disease systemic lupus erythematosus, antinuclear
            antibodies are developed with Sm specificity.
FEATURES             Location/Qualifiers
     source          1..1633
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     regulatory      143..149
                     /regulatory_class="ribosome_binding_site"
                     /note="ribosome binding site"
     CDS             151..510
                     /note="small nuclear riboprotein Sm-D"
                     /codon_start=1
                     /protein_id="AAA36620.1"
                     /translation="MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVK
                     MTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGR
                     GRGRGRGRGRGRGGPRR"
ORIGIN      1 bp upstream of EcoRI site.
        1 gaattccccc ccccccccca gtgctccgcg cgctcttgac gtccggagcc cctggagtag
       61 gcgcttccgg ccattcatac tgcagtcggt cagtgttcgg ttgaaggatt ctgtgtgctg
      121 tcggacccag agggtgacgg cgccgctagg atgaagctcg tgagattttt gatgaaattg
      181 agtcatgaaa ctgtaaccat tgaattgaag aacggaacac aggtccatgg aacaatcaca
      241 ggtgtggatg tcagcatgaa tacacatctt aaagctgtga aaatgaccct gaagaacaga
      301 gaacctgtac agctggaaac gctgagtatt cgaggaaata acattcggta ttttattcta
      361 ccagacagtt tacctctgga tacactactt gtggatgttg aacctaaggt gaaatctaag
      421 aaaagggaag ctgttgcagg aagaggcaga ggaagaggaa gaggaagagg acgtggccgt
      481 ggcagaggaa gagggggtcc taggcgataa tgtctctcaa gatttcaaag tcatatgaga
      541 tttgggatat tttttgtaca ggttgtgttt gtttatgtca gtttttaata aacataaatg
      601 tgggacagag ctgtctattt agtatatcaa agttttagta gtttcctcca cattcacgaa
      661 attaccacag tgagagctaa gcatttctac tgggcagttt catttttagt tgatcaggtt
      721 ttaagttttt gaactaaaat ttttcttttt ctttttatga tgaataaggt taaaataaaa
      781 gccttagaca aattaaattt ggcagagttt aattgagcaa aggacaattc acaaatcagg
      841 tagcccctga accataatag gctcagaggc ttcagcccag ctgcatagtt gaagatttat
      901 ggacagaagg aaagtgatgt atggaaaatg gaagtgagat acagcaacag ccggattagt
      961 tacagttcag cgtttgcctt atttgaatat ggtttgaaca gttcgctgtc tttggttggc
     1021 tgaaacttag tgattgccac aagagtaggg taccgtctgt ttacacgtcc agttaggcta
     1081 cagttctatg tactgagaaa cctttaagct gaacttgaga tatgtaaaga gactttaggc
     1141 taaacttaac aatatatata ggaatatatc ccttctactt cacatgcact gaatatgcat
     1201 tttattgctt tactcttcat tctgtggcac ctacccacag gggaagtaag aagtttgttt
     1261 tggtatttcg gaaactaaag tccttatggg atggggtcta gaattgattc tcctttcctg
     1321 agttttactc cacggagtct taggtacctg gtaaaaagtt gtcttctaaa ttaagggtca
     1381 ttgctttgtt gtctagctgc taatgtctta cttttgtttc ttttgctttt taatcagttc
     1441 ttaataggat atagttttat gttttccaag ttataacttg gagttaatgg tcactagatt
     1501 atcagttatg agcagtgtta aaatctccta ttaatgtgta atgtacctgt cagtgcctcc
     1561 tttattaagg ggttctttga gaataaaaga gaaaagacct actttatttg acagcaaaaa
     1621 aaaaaaggaa ttc
//
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