Sequence 63395 from Patent EP2199304

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Acute multi-sgRNA knockdown of KEOPS complex genes reproduces the microcephaly phenotype of the stable knockout zebrafish model. [PLoS One. 2018]
Acute multi-sgRNA knockdown of KEOPS complex genes reproduces the microcephaly phenotype of the stable knockout zebrafish model.
Jobst-Schwan T, Schmidt JM, Schneider R, Hoogstraten CA, Ullmann JFP, Schapiro D, Majmundar AJ, Kolb A, Eddy K, Shril S, et al. PLoS One. 2018; 13(1):e0191503. Epub 2018 Jan 18.
Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly. [Nat Genet. 2017]
Mutations in KEOPS-complex genes cause nephrotic syndrome with primary microcephaly.
Braun DA, Rao J, Mollet G, Schapiro D, Daugeron MC, Tan W, Gribouval O, Boyer O, Revy P, Jobst-Schwan T, et al. Nat Genet. 2017 Oct; 49(10):1529-1538. Epub 2017 Aug 14.
RFX transcription factors are essential for hearing in mice. [Nat Commun. 2015]
RFX transcription factors are essential for hearing in mice.
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, et al. Nat Commun. 2015 Oct 15; 6:8549. Epub 2015 Oct 15.