The complex allosteric and redox regulation of the fumarate hydratase and malate dehydratase reactions of Arabidopsis thaliana Fumarase 1 and 2 gives clues for understanding the massive accumulation of fumarate.
Zubimendi JP, Martinatto A, Valacco MP, Moreno S, Andreo CS, Drincovich MF, Tronconi MA. FEBS J. 2018 Jun; 285(12):2205-2224. Epub 2018 May 13.