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Homo sapiens klotho beta, mRNA (cDNA clone MGC:132531 IMAGE:8143874), complete cds

GenBank: BC104871.1

FASTA Graphics 

LOCUS       BC104871                3212 bp    mRNA    linear   PRI 21-JUL-2006
DEFINITION  Homo sapiens klotho beta, mRNA (cDNA clone MGC:132531
            IMAGE:8143874), complete cds.
ACCESSION   BC104871
VERSION     BC104871.1
KEYWORDS    MGC.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3212)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
   PUBMED   12477932
REFERENCE   2  (bases 1 to 3212)
  CONSRTM   NIH MGC Project
  TITLE     Direct Submission
  JOURNAL   Submitted (13-SEP-2005) National Institutes of Health, Mammalian
            Gene Collection (MGC), Bethesda, MD 20892-2590, USA
  REMARK    NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT     Contact: MGC help desk
            Email: cgapbs-r@mail.nih.gov
            Tissue Procurement: Mike Brownstein, NIMH
            cDNA Library Preparation: British Columbia Cancer Research Center
            cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
            DNA Sequencing by: Genome Sequence Centre,
            BC Cancer Agency, Vancouver, BC, Canada
            info@bcgsc.bc.ca
            Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
            Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
            Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
            Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
            Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
            Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
            Kim MacDonald,  Mike R. Mayo, Josh Moran, Diana Palmquist, JR
            Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
            Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
            
            Clone distribution: MGC clone distribution information can be found
            through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
            Series: IRCB Plate: 3 Row: e Column: 24.
FEATURES             Location/Qualifiers
     source          1..3212
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /clone="MGC:132531 IMAGE:8143874"
                     /tissue_type="Liver, PCR rescued clones"
                     /clone_lib="NIH_MGC_291"
                     /note="Vector: pCR4-TOPO with reversed insert; Clone
                     identification sequence tag: GAAAGCCC"
     gene            1..3212
                     /gene="KLB"
                     /db_xref="GeneID:152831"
                     /db_xref="HGNC:HGNC:15527"
     CDS             22..3156
                     /gene="KLB"
                     /codon_start=1
                     /product="klotho beta"
                     /protein_id="AAI04872.1"
                     /db_xref="GeneID:152831"
                     /db_xref="HGNC:HGNC:15527"
                     /translation="MKPGCAAGSPGNEWIFFSTDEITTRYRNTMSNGGLQRSVILSAL
                     ILLRAVTGFSGDGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKK
                     DGKGPSIWDHFIHTHLKNVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFP
                     DGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIF
                     NDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKA
                     HSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNRSENTMDIFKCQQSMVSVLGWFANPI
                     HGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNV
                     SLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLD
                     EIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGF
                     SLKESTPDVQGQFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEG
                     VRLKTRPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYR
                     CVVSEGLKLGISAMVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELG
                     DLVKLWITINEPNRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSL
                     SLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGL
                     SSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRL
                     SSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGIDDQALEDDRLRKYYLGKYLQEV
                     LKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTSDFKAKSSIQFYNKVISSRGFPFENS
                     SSRCSQTQENTECTVCLFLVQKKPLIFLGCCFFSTLVLLLSIAIFQRQKRRKFWKAKN
                     LQHIPLKKGKRVVS"
ORIGIN      
        1 cagtccagca gttggtggca aatgaagcca ggctgtgcgg caggatctcc agggaatgaa
       61 tggattttct tcagcactga tgaaataacc acacgctata ggaatacaat gtccaacggg
      121 ggattgcaaa gatctgtcat cctgtcagca cttattctgc tacgagctgt tactggattc
      181 tctggagatg gaagagctat atggtctaaa aatcctaatt ttactccggt aaatgaaagt
      241 cagctgtttc tctatgacac tttccctaaa aactttttct ggggtattgg gactggagca
      301 ttgcaagtgg aagggagttg gaagaaggat ggaaaaggac cttctatatg ggatcatttc
      361 atccacacac accttaaaaa tgtcagcagc acgaatggtt ccagtgacag ttatattttt
      421 ctggaaaaag acttatcagc cctggatttt ataggagttt ctttttatca attttcaatt
      481 tcctggccaa ggcttttccc cgatggaata gtaacagttg ccaacgcaaa aggtctgcag
      541 tactacagta ctcttctgga cgctctagtg cttagaaaca ttgaacctat agttacttta
      601 taccactggg atttgccttt ggcactacaa gaaaaatatg gggggtggaa aaatgatacc
      661 ataatagata tcttcaatga ctatgccaca tactgtttcc agatgtttgg ggaccgtgtc
      721 aaatattgga ttacaattca caacccatat ctagtggctt ggcatgggta tgggacaggt
      781 atgcatgccc ctggagagaa gggaaattta gcagctgtct acactgtggg acacaacttg
      841 atcaaggctc actcgaaagt ttggcataac tacaacacac atttccgccc acatcagaag
      901 ggttggttat cgatcacgtt gggatctcat tggatcgagc caaaccggtc ggaaaacacg
      961 atggatatat tcaaatgtca acaatccatg gtttctgtgc ttggatggtt tgccaaccct
     1021 atccatgggg atggcgacta tccagagggg atgagaaaga agttgttctc cgttctaccc
     1081 attttctctg aagcagagaa gcatgagatg agaggcacag ctgatttctt tgccttttct
     1141 tttggaccca acaacttcaa gcccctaaac accatggcta aaatgggaca aaatgtttca
     1201 cttaatttaa gagaagcgct gaactggatt aaactggaat acaacaaccc tcgaatcttg
     1261 attgctgaga atggctggtt cacagacagt cgtgtgaaaa cagaagacac cacggccatc
     1321 tacatgatga agaatttcct cagccaggtg cttcaagcaa taaggttaga tgaaatacga
     1381 gtgtttggtt atactgcctg gtctctcctg gatggctttg aatggcagga tgcttacacc
     1441 atccgccgag gattatttta tgtggatttt aacagtaaac agaaagagcg gaaacctaag
     1501 tcttcagcac actactacaa acagatcata cgagaaaatg gtttttcttt aaaagagtcc
     1561 acgccagatg tgcagggcca gtttccctgt gacttctcct ggggtgtcac tgaatctgtt
     1621 cttaagcccg agtctgtggc ttcgtcccca cagttcagcg atcctcatct gtacgtgtgg
     1681 aacgccactg gcaacagact gttgcaccga gtggaagggg tgaggctgaa aacacgaccc
     1741 gctcaatgca cagattttgt aaacatcaaa aaacaacttg agatgttggc aagaatgaaa
     1801 gtcacccact accggtttgc tctggattgg gcctcggtcc ttcccactgg caacctgtcc
     1861 gcggtgaacc gacaggccct gaggtactac aggtgcgtgg tcagtgaggg gctgaagctt
     1921 ggcatctccg cgatggtcac cctgtattat ccgacccacg cccacctagg cctccccgag
     1981 cctctgttgc atgccgacgg gtggctgaac ccatcgacgg ccgaggcctt ccaggcctac
     2041 gctgggctgt gcttccagga gctgggggac ctggtgaagc tctggatcac catcaacgag
     2101 cctaaccggc taagtgacat ctacaaccgc tctggcaacg acacctacgg ggcggcgcac
     2161 aacctgctgg tggcccacgc cctggcctgg cgcctctacg accggcagtt caggccctca
     2221 cagcgcgggg ccgtgtcgct gtcgctgcac gcggactggg cggaacccgc caacccctat
     2281 gctgactcgc actggagggc ggccgagcgc ttcctgcagt tcgagatcgc ctggttcgcc
     2341 gagccgctct tcaagaccgg ggactacccc gcggccatga gggaatacat tgcctccaag
     2401 caccgacggg ggctttccag ctcggccctg ccgcgcctca ccgaggccga aaggaggctg
     2461 ctcaagggca cggtcgactt ctgcgcgctc aaccacttca ccactaggtt cgtgatgcac
     2521 gagcagctgg ccggcagccg ctacgactcg gacagggaca tccagtttct gcaggacatc
     2581 acccgcctga gctcccccac gcgcctggct gtgattccct ggggggtgcg caagctgctg
     2641 cggtgggtcc ggaggaacta cggcgacatg gacatttaca tcaccgccag tggcatcgac
     2701 gaccaggctc tggaggatga ccggctccgg aagtactacc tagggaagta ccttcaggag
     2761 gtgctgaaag catacctgat tgataaagtc agaatcaaag gctattatgc attcaaactg
     2821 gctgaagaga aatctaaacc cagatttgga ttcttcacat ctgattttaa agctaaatcc
     2881 tcaatacaat tttacaacaa agtgatcagc agcaggggct tcccttttga gaacagtagt
     2941 tctagatgca gtcagaccca agaaaataca gagtgcactg tctgcttatt ccttgtgcag
     3001 aagaaaccac tgatattcct gggttgttgc ttcttctcca ccctggttct actcttatca
     3061 attgccattt ttcaaaggca gaagagaaga aagttttgga aagcaaaaaa cttacaacac
     3121 ataccattaa agaaaggcaa gagagttgtt agctaaactg atctgtctgc atgatagaca
     3181 gtttaaaaat tcatcccagt tccatatgct gg
//
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Reference sequence information

  • RefSeq mRNA
    See reference mRNA sequence for the KLB gene (NM_175737.4).

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