Adenine is an anti-inflammatory metabolite found to be more abundant in M-CSF over GM-CSF-differentiated human macrophages.
Harber KJ, Nguyen TA, Schomakers BV, Heister DAF, de Vries HE, van Weeghel M, Van den Bossche J, de Winther MPJ. Immunol Lett. 2024 Feb; 265:23-30. Epub 2023 Dec 22.