Homo sapiens phospholipase C, gamma 2 (phosphatidylinositol-specific), - Nucleotide

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Articles about the PLCG2 gene

The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation. [Biochim Biophys Acta Mol Basis...]
The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation.
Bull D, Matte JC, Navarron CM, McIntyre R, Whiting P, Katan M, Ducotterd F, Magno L. Biochim Biophys Acta Mol Basis Dis. 2024 Feb; 1870(2):166978. Epub 2023 Dec 6.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. [Cell. 2023]
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, et al. Cell. 2023 Oct 26; 186(22):4898-4919.e25. Epub 2023 Oct 11.
PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants. [J Allergy Clin Immunol. 2024]
PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants.
Baysac K, Sun G, Nakano H, Schmitz EG, Cruz AC, Fisher C, Bailey AC, PLCG2-Immune Dysregulation Working Group, Mace E, Milner JD, et al. J Allergy Clin Immunol. 2024 Jan; 153(1):230-242. Epub 2023 Sep 26.

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Reference sequence information

RefSeq alternative splicing
See 4 reference mRNA sequence splice variants for the PLCG2 gene.

More about the PLCG2 gene

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bis...
Also Known As: APLAID, FCAS3, PLC-IV, ...

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Homo sapiens phospholipase C, gamma 2 (phosphatidylinositol-specific), mRNA (cDNA clone MGC:1680 IMAGE:2989389), complete cds

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Articles about the PLCG2 gene

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