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Homo sapiens proline 4-hydroxylase (PH-4) mRNA, complete cds

GenBank: AY198406.1

FASTA Graphics 

LOCUS       AY198406                1509 bp    mRNA    linear   PRI 26-FEB-2003
DEFINITION  Homo sapiens proline 4-hydroxylase (PH-4) mRNA, complete cds.
ACCESSION   AY198406
VERSION     AY198406.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Oehme,F., Ellinghaus,P., Kolkhof,P., Smith,T.J., Ramakrishnan,S.,
            Hutter,J., Schramm,M. and Flamme,I.
  TITLE     Overexpression of PH-4, a novel putative proline 4-hydroxylase,
            modulates activity of hypoxia-inducible transcription factors
  JOURNAL   Biochem. Biophys. Res. Commun. 296 (2), 343-349 (2002)
   PUBMED   12163023
REFERENCE   2  (bases 1 to 1509)
  AUTHORS   Oehme,F., Ellinghaus,P., Kolkhof,P., Smith,T.J., Ramakrishnan,S.,
            Hutter,J., Schramm,M. and Flamme,I.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2002) Target Discovery, Lion Bioscience Research
            Incorporated, 141 Portland Street 10th Floor, Cambridge, MA 02139,
            USA
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
     gene            1..1509
                     /gene="PH-4"
     CDS             1..1509
                     /gene="PH-4"
                     /function="modulates activity of hypoxia-inducible
                     transcription factors"
                     /codon_start=1
                     /product="proline 4-hydroxylase"
                     /protein_id="AAO43431.1"
                     /translation="MAAAAVTGQRPETAAAEEASRPQWAPPDHCQAQAAAGLGDGEDA
                     PVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGDESSDPGPQHRAQGP
                     GPEPTLGPLTRLEGIKVGHERKVQLVTDRDHFIRTLSLKPLLFEIPGFLTDEECRLII
                     HLAQMKGLQRSQILPTEEYEEAMSTMQVSQLDLFRLLDQNRDGHLQLREVLAQTRLGN
                     GWWMTPESIQEMYAAIKADPDADGVLSLQEFSNMDLRDFHKYMRSHKAESSELVRNSH
                     HTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPV
                     YPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQ
                     DDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGT
                     KWIANNWINVDPSRARQALFQQEMARLAREGGTDSQPEWALDRAYRDARVEL"
ORIGIN      
        1 atggcggcag cggcggtgac aggccagcgg cctgagaccg cggcggccga ggaggcctcg
       61 aggccgcagt gggcgccgcc agaccactgc caggctcagg cggcggccgg gctgggcgac
      121 ggcgaggacg caccggtgcg tccgctgtgc aagccccgcg gcatctgctc gcgcgcctac
      181 ttcctggtgc tgatggtgtt cgtgcacctg tacctgggta acgtgctggc gctgctgctc
      241 ttcgtgcact acagcaacgg cgacgaaagc agcgatcccg ggccccaaca ccgtgcccag
      301 ggccccgggc ccgagcccac cttaggtccc ctcacccggc tggagggcat caaggtgggg
      361 cacgagcgta aggtccagct ggtcaccgac agggatcact tcatccgaac cctcagcctc
      421 aagccgctgc tcttcgaaat ccccggcttc ctgactgatg aagagtgtcg gctcatcatc
      481 catctggcgc agatgaaggg gttacagcgc agccagatcc tgcctactga agagtatgaa
      541 gaggcaatga gcactatgca ggtcagccag ctggacctct tccggctgct ggaccagaac
      601 cgtgatgggc accttcagct ccgtgaggtt ctggcccaga ctcgcctggg aaatggatgg
      661 tggatgactc cagagagcat tcaggagatg tacgccgcga tcaaggctga ccctgatgct
      721 gacggagtgc tgagtctgca ggagttctcc aacatggacc ttcgggactt ccacaagtac
      781 atgaggagcc acaaggcaga gtccagtgag ctggtgcgga acagccacca tacctggctc
      841 taccagggtg agggtgccca ccacatcatg cgtgccatcc gccagagggt gctgcgcctc
      901 actcgcctgt cgcctgagat cgtggagctc agcgagccgc tgcaggttgt tcgatatggt
      961 gaggggggcc actaccatgc ccacgtggac agtgggcctg tgtacccaga gaccatctgc
     1021 tcccatacca agctggtagc caacgagtct gtacccttcg agacctcctg ccgctacatg
     1081 acagtgctgt tttatttgaa caacgtcact ggtgggggcg agactgtttt ccctgtagca
     1141 gataacagaa cctacgatga aatgagtctg attcaggatg acgtggacct ccgtgacaca
     1201 cggaggcact gtgacaaggg aaacctgcgt gtcaagcccc aacagggcac agcagtcttc
     1261 tggtacaact acctgcctga tgggcaaggt tgggtgggtg acgtagacga ctactcgctg
     1321 cacgggggct gcctggtcac gcgcggcacc aagtggattg ccaacaactg gattaatgtg
     1381 gaccccagcc gagcgcggca agcgctgttc caacaggaga tggcccgcct tgcccgagaa
     1441 gggggcaccg actcacagcc cgagtgggct ctggaccggg cctaccgcga tgcgcgcgtg
     1501 gaactctga
//
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