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GenBank: AY198406.1
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LOCUS AY198406 1509 bp mRNA linear PRI 26-FEB-2003 DEFINITION Homo sapiens proline 4-hydroxylase (PH-4) mRNA, complete cds. ACCESSION AY198406 VERSION AY198406.1 KEYWORDS . SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 1509) AUTHORS Oehme,F., Ellinghaus,P., Kolkhof,P., Smith,T.J., Ramakrishnan,S., Hutter,J., Schramm,M. and Flamme,I. TITLE Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors JOURNAL Biochem. Biophys. Res. Commun. 296 (2), 343-349 (2002) PUBMED 12163023 REFERENCE 2 (bases 1 to 1509) AUTHORS Oehme,F., Ellinghaus,P., Kolkhof,P., Smith,T.J., Ramakrishnan,S., Hutter,J., Schramm,M. and Flamme,I. TITLE Direct Submission JOURNAL Submitted (17-DEC-2002) Target Discovery, Lion Bioscience Research Incorporated, 141 Portland Street 10th Floor, Cambridge, MA 02139, USA FEATURES Location/Qualifiers source 1..1509 /organism="Homo sapiens" /mol_type="mRNA" /db_xref="taxon:9606" gene 1..1509 /gene="PH-4" CDS 1..1509 /gene="PH-4" /function="modulates activity of hypoxia-inducible transcription factors" /codon_start=1 /product="proline 4-hydroxylase" /protein_id="AAO43431.1" /translation="MAAAAVTGQRPETAAAEEASRPQWAPPDHCQAQAAAGLGDGEDA PVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGDESSDPGPQHRAQGP GPEPTLGPLTRLEGIKVGHERKVQLVTDRDHFIRTLSLKPLLFEIPGFLTDEECRLII HLAQMKGLQRSQILPTEEYEEAMSTMQVSQLDLFRLLDQNRDGHLQLREVLAQTRLGN GWWMTPESIQEMYAAIKADPDADGVLSLQEFSNMDLRDFHKYMRSHKAESSELVRNSH HTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPV YPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQ DDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGT KWIANNWINVDPSRARQALFQQEMARLAREGGTDSQPEWALDRAYRDARVEL" ORIGIN 1 atggcggcag cggcggtgac aggccagcgg cctgagaccg cggcggccga ggaggcctcg 61 aggccgcagt gggcgccgcc agaccactgc caggctcagg cggcggccgg gctgggcgac 121 ggcgaggacg caccggtgcg tccgctgtgc aagccccgcg gcatctgctc gcgcgcctac 181 ttcctggtgc tgatggtgtt cgtgcacctg tacctgggta acgtgctggc gctgctgctc 241 ttcgtgcact acagcaacgg cgacgaaagc agcgatcccg ggccccaaca ccgtgcccag 301 ggccccgggc ccgagcccac cttaggtccc ctcacccggc tggagggcat caaggtgggg 361 cacgagcgta aggtccagct ggtcaccgac agggatcact tcatccgaac cctcagcctc 421 aagccgctgc tcttcgaaat ccccggcttc ctgactgatg aagagtgtcg gctcatcatc 481 catctggcgc agatgaaggg gttacagcgc agccagatcc tgcctactga agagtatgaa 541 gaggcaatga gcactatgca ggtcagccag ctggacctct tccggctgct ggaccagaac 601 cgtgatgggc accttcagct ccgtgaggtt ctggcccaga ctcgcctggg aaatggatgg 661 tggatgactc cagagagcat tcaggagatg tacgccgcga tcaaggctga ccctgatgct 721 gacggagtgc tgagtctgca ggagttctcc aacatggacc ttcgggactt ccacaagtac 781 atgaggagcc acaaggcaga gtccagtgag ctggtgcgga acagccacca tacctggctc 841 taccagggtg agggtgccca ccacatcatg cgtgccatcc gccagagggt gctgcgcctc 901 actcgcctgt cgcctgagat cgtggagctc agcgagccgc tgcaggttgt tcgatatggt 961 gaggggggcc actaccatgc ccacgtggac agtgggcctg tgtacccaga gaccatctgc 1021 tcccatacca agctggtagc caacgagtct gtacccttcg agacctcctg ccgctacatg 1081 acagtgctgt tttatttgaa caacgtcact ggtgggggcg agactgtttt ccctgtagca 1141 gataacagaa cctacgatga aatgagtctg attcaggatg acgtggacct ccgtgacaca 1201 cggaggcact gtgacaaggg aaacctgcgt gtcaagcccc aacagggcac agcagtcttc 1261 tggtacaact acctgcctga tgggcaaggt tgggtgggtg acgtagacga ctactcgctg 1321 cacgggggct gcctggtcac gcgcggcacc aagtggattg ccaacaactg gattaatgtg 1381 gaccccagcc gagcgcggca agcgctgttc caacaggaga tggcccgcct tgcccgagaa 1441 gggggcaccg actcacagcc cgagtgggct ctggaccggg cctaccgcga tgcgcgcgtg 1501 gaactctga //
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