The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs.
Liu L, Lucas RM, Nanson JD, Li Y, Whitfield J, Curson JEB, Tuladhar N, Alexandrov K, Mobli M, Sweet MJ, et al. J Biol Chem. 2022 May; 298(5):101857. Epub 2022 Mar 22.