Homo sapiens methyl-CpG binding domain protein 4 variant mRNA, complet - Nucleotide

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Familial uveal melanoma and other tumors in 25 families with monoallelic germline MBD4 variants. [J Natl Cancer Inst. 2024]
Familial uveal melanoma and other tumors in 25 families with monoallelic germline MBD4 variants.
Villy MC, Le Ven A, Le Mentec M, Masliah-Planchon J, Houy A, Bièche I, Vacher S, Vincent-Salomon A, Dubois d'Enghien C, Schwartz M, et al. J Natl Cancer Inst. 2024 Apr 5; 116(4):580-587.
MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density. [J Exp Clin Cancer Res. 2023]
MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density.
Papin C, Ibrahim A, Sabir JSM, Le Gras S, Stoll I, Albiheyri RS, Zari AT, Bahieldin A, Bellacosa A, Bronner C, et al. J Exp Clin Cancer Res. 2023 Nov 14; 42(1):301. Epub 2023 Nov 14.
Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis. [Cell Rep. 2022]
Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.
Li H, Zhang J, Ke JR, Yu Z, Shi R, Gao SS, Li JF, Gao ZX, Ke CS, Han HX, et al. Cell Rep. 2022 Dec 20; 41(12):111834.

RefSeq alternative splicing
See 9 reference mRNA sequence splice variants for the MBD4 gene.

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Nucleotide