LOCUS AF082221 9016 bp DNA linear ROD 05-MAY-2003
DEFINITION Mus musculus lipocalin precursor (EP17) gene, promoter region and
complete cds.
ACCESSION AF082221
VERSION AF082221.2
KEYWORDS .
SOURCE Mus musculus (house mouse)
ORGANISM Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE 1 (bases 1 to 9016)
AUTHORS Lareyre,J.J., Winfrey,V.P., Kasper,S., Ong,D.E., Matusik,R.J.,
Olson,G.E. and Orgebin-Crist,M.C.
TITLE Gene duplication gives rise to a new 17-kilodalton lipocalin that
shows epididymal region-specific expression and testicular
factor(s) regulation
JOURNAL Endocrinology 142 (3), 1296-1308 (2001)
PUBMED 11181548
REFERENCE 2 (bases 1 to 9016)
AUTHORS Suzuki,K., Matusik,R.J. and Orgebin-Crist,M.C.
TITLE 5' flanking region of the mouse epididymal 17 kDa lipocalin (mEP17)
gene
JOURNAL Unpublished
REFERENCE 3 (bases 1 to 9016)
AUTHORS Lareyre,J.J., Ong,D.E., Matusik,R.J. and Orgebin-Crist,M.C.
TITLE Direct Submission
JOURNAL Submitted (04-AUG-1998) Obstetrics and Gynecology, Center for
Reproductive Biology Research, Vanderbilt University, 1161 21st
Avenue South, MCN Room D2303, Nashville, TN 37232-2633, USA
REFERENCE 4 (bases 1 to 9016)
AUTHORS Suzuki,K., Matusik,R.J. and Orgebin-Crist,M.C.
TITLE Direct Submission
JOURNAL Submitted (11-JAN-2002) Obstetrics and Gynecology, Center for
Reproductive Biology Research, Vanderbilt University, 1161 21st
Avenue South, MCN Room D2303, Nashville, TN 37232-2633, USA
REMARK Sequence update by submitter
COMMENT On May 5, 2003 this sequence version replaced AF082221.1.
FEATURES Location/Qualifiers
source 1..9016
/organism="Mus musculus"
/mol_type="genomic DNA"
/strain="129/SvJ"
/db_xref="taxon:10090"
/chromosome="2"
/map="2A3 to 2B"
/clone="BAC 10983"
gene 1..8383
/gene="EP17"
regulatory 1..5293
/regulatory_class="promoter"
/gene="EP17"
regulatory 5222..5225
/regulatory_class="CAAT_signal"
/gene="EP17"
regulatory 5268..5273
/regulatory_class="TATA_box"
/gene="EP17"
mRNA join(5294..5408,6337..6467,6919..6989,7285..7389,
7468..7557,7655..7680,8269..8383)
/gene="EP17"
/product="epididymal 17 kDa protein precursor"
CDS join(5316..5408,6337..6467,6919..6989,7285..7389,
7468..7557,7655..7680,8269..8280)
/gene="EP17"
/note="epididymal 17 kDa protein precursor"
/codon_start=1
/product="lipocalin precursor"
/protein_id="AAK58105.1"
/translation="MEARLLSNVCGFFLVFLLQAESTRVELVPEKIAGFWKEVAVASD
QKLVLKAQRRVEGLFLTFSGGNVTVKAVYNSSGSCVTESSLGSERDTVGEFAFPGNRE
IHVLDTDYERYTILKLTLLWQGRNFHVLKYFTRSLENEDEPGFWLFREMTADQGLYML
ARHGRCAELLKEGLV"
sig_peptide 5316..5381
/gene="EP17"
ORIGIN
1 gatatctagc atgtttccag tttctggata ttttgaataa agctactatg aacacagttg
61 agccagtgtc cttgtgggat ggtggagtat cttttgggta tatgcccagg agtgatatag
121 cagggtcttg gggtagaact atttccagtt tattgagaaa ctgccacatt gatttttcag
181 agtggttgta ccagttttta ctcccaccag caatggagga gtgttccctt gtgttccata
241 ccctgtcact tgaggtgttt ttttgttttt gttttaagat tttttttttc gagacagggt
301 ttctctgtat agtcctgtct gtcctggaac tcactttgta gactaggctg gcctagaact
361 cagaaatccg cctgcctctg cctcccaagt gctgggatta aaggcgtgcg ccaccacacc
421 cggctgtttt aagatttttt taaaaaaaga tttatttata ataataaata tctaagtaca
481 ctgtagctgt cttcagacac accagaagag ggcatcagat ctcattacag atggttgtga
541 gccaccatgt ggttgctggg atttgaactc aggatctttg gaagagcagt cagtgctctt
601 aaccactgag ccatctctac agcccatcac ttgagttttt gaatcttatc cattctgaca
661 gttgtaagat ggaatctcag agtccttttg atttgcatct ccctgataac taaggacgtt
721 gaacatttct ttaagggctt ctcagccatt cgagattcct gtttaactag gaaactcttt
781 actaactcct ttcttgcctg tcacagccac tgtgaagggt tcacacataa tcgcttctct
841 gcatcgcgta ggtcctaaga ccccagtccc caggccctca aggccttttc agacttctac
901 ccaacaatgg gtcttctggg taacatgatg gtaacaccac ccaaatcagt tactagttga
961 gctagcccac cagagcacct gcctaggtca tcccttcagt tctggagcat gtaggtctac
1021 attgcctaga cccccttcta tctccagcac cggtgaggag cccctgatgg ggataattct
1081 ctaaccagct ctgtggggat tgtaggggtg agcaggaccc aagcacctag tgggtgtgtc
1141 tgagagaaag gaggaaaatc aatgatcttc ccatgtgcgt ttctctgggt aaggaggtac
1201 tcaggtgtcc tgagtgacca gtgccaacat tctcgggcta tgtgcagggt gagttttctt
1261 ctgagcttgg gtcagcaaga tcctatccct gaaatctgtg atccctacta cctgtcgagt
1321 ctcatgctta tggttttagc ttagacatgt ctggtagaag atgccaccct ggtgtcttgg
1381 ggccatcata ataagccaag gcaaagagac agaaagaatt ctcttttagt ccaagagacc
1441 gaagtcagga atccatgtgt gtggaggcta gaggagggct cttgccaatc tgcaccccca
1501 acccccagct tctggtcttt cttctgttct gggcagtctt aatcttgact gcatcactaa
1561 tatctgcctc tttcttctgc ccatctgtgt ctgaattctt ccattcataa ggatgctgtc
1621 tttgggttag ggccatctga acctgtctgc agaaaccttg tcttcaagta agatattgtt
1681 tggaggttct gggtggggga tactattcaa tccagtgtac cccatgtttt gctaaccttt
1741 gggcccccct tctcagggct tgtaccatat ctttaattgt atcatcctgt tcccaagaac
1801 cctgaaaggg cagaactatt tttcatctac tgctccacta cagggttagg gtagaagtcc
1861 ttggcatctt gatacaggca ggttcatggg gaggcctacc caaccaaacc aatgtagaaa
1921 gctgcccaat tcctacccaa gctcattgct aacaattttg gcactcacaa agccacagta
1981 gtagatgaca tgtgagtgta taaaagtcag tggatagagg gggtgggtgt aataccgtat
2041 ggcttatcct gggatggaga ctttgtggta tttcttgttc ttttcccagc ctcctagttc
2101 tctgcatgct ggtactttgc aggtcatgat aggcctctta ttatcctttc ctcttgcctg
2161 cttaccctga atgcctgctg ttttgacagt ccatggatct aaacacctgt gctgagctta
2221 catgttctcc actatcaggt agttttgaaa acgtaagaag ttagactcaa tgtcaaatca
2281 ccctgtcatt tttcctgtta ctatggtctt ggtctctctt ctcagggcct ggcaaggctt
2341 aggggttact agtcctgtaa gaattaggga tccagaagta tggcaggtct ctatggtctc
2401 tgggaaggtg ccttggagag gcatctctag tcgggtcagt ggcagtgtgg gaagttttta
2461 ctggtttata gatgctttgg tgacaggatt atctttcctt gcctttgtgg gttggcagcc
2521 ttggggggca gtgcctagct tgtggggagt atggaggatg tttgacaaag gactggtgat
2581 ggagtgattg tgccctttta gggtaggatg aacctggagt tgccaacctc aagagtgtca
2641 ctctcactgt gatctttagg gactgagaga tcctcttggg tcccacctcc ttccgtcctg
2701 tgttccttct cttgctcttc tcctttcacc caataaacag attcagcatc cgcatggctc
2761 tttgaccctt tggagatgcc cttgggcaga tcatagtgaa ctctttcttc atcccagccc
2821 tctggccact tagggttctc ctcgagagtg ggcaggatgt ttcattcaaa tttggtgaag
2881 ggaggttgct gcatccacag ggaagactga gcacagcata tgtggtatcc acgaggtcac
2941 agtgtctttg aaaccaaggt gcctactgag gatgggttgt aggctctagg ctcccttggg
3001 tctcagaaat tgtatgtatg gatatatgaa ctggaaagca ggagggccat aatgctaggt
3061 tttgattccc atctcctcct ttgatcttgg acaaatggtt tcgacctttg ggagcctaag
3121 aaataggtca gggcagtggt cactgtgctt gaagaccttg ctaggctagc tgtcatgtga
3181 tttccatgac agacctcctg gatacacata gctagctgca tccattcttt tttctcagat
3241 tgagacactg aggcacagaa gctggacagg ttactcaagg tcacacgatg gacaaattca
3301 ggggtggcat gatgtagtct ctgtgctgct cttgaacaag atgtggggta cgggggttcc
3361 tttccaggta ttatcactgc tctcgtcttc atgtcacaga attcccattc tccagtggat
3421 ctagttctac ttcaaagtcc aggcatggaa acaggaaggg gctggttctg ctccattgct
3481 tatctgtctg tggtcctcag acaacaagaa ctggaagcaa ttagccctca tagctgctgc
3541 cctcatcctg tgccagtcac ccagagaacc aggtgccatc cacccacatc tctttccctc
3601 actccagcca aacccctctc tgtatcccca agggccctgg cttgtcagtc tgttgttggg
3661 accagcaggc cctcagcttc cctcccgatg ccccaaagtc tttggatggt tccttctagt
3721 gctcactgtg cattctctcc taactcatct cttatgccgt cctcacaggc caccctaatg
3781 tcttctgtgc ctggttccct ctggagggtg ggcttcagtg gatttcctgt gagctgtcca
3841 ggtcttgagc agctccaggt gggtccaaaa gattagactg ttcctacagg atgaggggtg
3901 ctgacctggg tagagctgtt ttggggtgcc ctgggacact caagacctat ttctctgcta
3961 cacaagttgg aggttagaga tttgggtcac aaggtgacta agtcattttg ggggtgtcag
4021 tcagggaggg ctttgcattc agggtgcttc atggtccctg tttatcctgt ttctttcctt
4081 tttatttgga ggaaatagac aattgtgaga aaaactaata tttttagttt ttttattttc
4141 ctagcgaatg ggagactttg ttttagtatc aatcacaaat aaagttgatt ttaaagataa
4201 aagttgtctg ccttaaaaaa attctctgtg gtctgagagg tgtttgtttg tttctgagag
4261 gtgtgaaaaa ccttgtcgtt ggggctggga agatagctca gctggtaaag tactttcttc
4321 agaacccata taaaagccag gcatggtggt gtgtatttga aatcacatgg tgagtgctgg
4381 acagacagag atagtgggat ctctggggct cactggctag gcagcctaga ctactcagca
4441 cgcttcaggt tagtaagaaa ctctgtctca aaaaataagt aaccagccaa ttgaccaacc
4501 aatcaataaa ctaactaact agctagctag ctagctagct aactaactaa ctaactaact
4561 aactaactaa tgaagcaaaa caaatgaaaa cacaaagtga cttgtactaa aggaacaaca
4621 cctgaggttg aactctggct tccacatcca tgtgactatt tgtatgcttt ccccaaccaa
4681 gaacaaagac atgaacacta tatacacaga gacacacaga cacacaaata ccacaaacat
4741 acacaccaca cacaaacacc acatacaaac atacatacca cacacaaata ccacaaacat
4801 atataacaca cacatacaca gataccacat acaaacatat ataacacacc acacagatag
4861 agatactata taaaaaaata tacacacaca gaatggaggg aatgcagaat gctgcaaggt
4921 ataaggtata aggttcctgg ttggagactc aggcctcctt gttcagttca atattttgtt
4981 attgttttaa gcttattgtt acaaatggag aaactgagat aaatagcttg tccagttcat
5041 agctcagagc gtggggctgg acttggttgg tgcagtctta ctgcatagtt catcactgtc
5101 cacatgctag gatggaggca gcttaactgt catcttagct tggtcctaca cctctctgga
5161 tgggggttga tagcatttga gcagaagctg agtctctgag cagctgacag ccagctttgt
5221 ccaatgacat tctctaagtg gttgcacatg cttgcacact ctccaaatat aagctcccac
5281 cttgcataaa cagaagccac aagccaggcc ctgagatgga agctaggctg ctgagcaatg
5341 tctgcggatt cttcctggtg ttcctgctac aagctgagtc taccagggtg gagcttgtac
5401 cagagaaggt gcctctttct tcttggcttc gaagccctac tggggcttaa tggaaagttg
5461 gacagggagg gagcagagtg tacaaccatt gaagtctctc ttcccttcca tctaactcct
5521 gttggttgca gcctagctgt caggggccag acctactctt ggggcctcca tccctaagac
5581 agcaggcagt gtgagtccct agtagacctc tgaggtctgt ggatctctcc cctctctgag
5641 ttctctcatg ttccacctgt cttgaggcgg agttgctgtc cacaagctgg tcacttcaag
5701 ggtccttggt gatttacaaa tttggggtcc cttcctgctt cctggttcat agggttccta
5761 agaccctatc cctgtgcact gtggagccag aagaggactt ctccagggca ggcagcttgt
5821 tgcttgaatt cttccttcta tgccccaatc ccccattctt cctgagactt ccagactcac
5881 actgtaacgt cagaggggtc aggttttggg ggatacagat tattgtctct tgtaacagta
5941 atgagtttct aaaagtttca ggtgatgtcc tgtgctctga gaacattgcc actgcaggag
6001 atcatgatcc tggggaggct gagattagta gaaccatgct tcattcagta tgaaagctgt
6061 aagcctggat gcttgctccc cacacccttg ctggaaaggt ctcctggcaa accaggagtg
6121 aacattgtgt cagtgtcttc tggaagggac atttcccctg ggaaggaaaa ctcggccgag
6181 aataagtggc ttccagtctc acgactatgg attgcccctc aagcccatcc aactgctgcc
6241 cgagcgtccc tgaaacaccc tctccagccc aggggctgga gacccagttc agcttggctg
6301 agcaaagcca gggatatctc tagttctgtt ctctagattg caggattctg gaaggaagtg
6361 gctgttgctt ctgaccaaaa actggtgctg aaggctcaaa ggagggtaga gggcttgttc
6421 ctcaccttca gtggggggaa tgtcactgtg aaagccgtgt acaacaggta agagacttgg
6481 gtcactaggg atgtggcctg ctgggaagga agagccatat atgtagttga aattagacaa
6541 ggctatacct cttataatgg tgggatcatc agtatgtggg ctagcctttt ccatgtctat
6601 ctgcttgggt cttccaactc cagagaaagc tagatcttag gctcttagat ctgcctttct
6661 accaaaatgt aagcaaagac tttagataaa gccctattgc tttataaggg agagtgggta
6721 gtagtagttg cctgactctc tgaaggagag aggctgggga gcctgtccca tgcatggccc
6781 cttctgcata gaccctagac tcctgcatgg tcatgagctt gacagcatcc tttttgaatg
6841 tgtgcagcac tcaggaatgt gcccagaagg tggaatgcag gctggcaggt tcttaacaag
6901 cactatgatg cttttcagct caggaagttg tgtgacagaa agttcactgg gttcagaaag
6961 agacactgtg ggggaatttg cttttcctgg taagtactgt tgccttgttg ctgaagttgc
7021 agctgctgtc tgagcctgga catctccccc tggcctcgtt cctgtgcctt caagattctc
7081 aggccctgga ctccagcccc ctcatctcta ctagtgtact gagttgatct tcagaatttg
7141 tcttctcaga tgtcacaggc aggtcccagc actaggcaga aatagaaagg agttagattc
7201 tgcaaatcca gccttcaagg tcagctccct ggagtgttca ggtctgagca agcctcctta
7261 accctgccac tgccactcct gaaggtaaca gggagatcca cgtgctggac acggactatg
7321 agcgctacac catcctgaag ttgaccctgc tctggcaggg tagaaacttc catgtgctca
7381 agtacttcag taagttccgc ctgggctggc tctgccctgc gactaccttc cttcaggctg
7441 ccagccccac tctgttgtgc cccacagctc ggagccttga gaacgaggat gagccaggct
7501 tctggctgtt ccgggaaatg acagcagacc aaggccttta catgttggcc cgacatggtg
7561 agtatagcat cttggggagg atgctgtacc aggctcctgt gatggggtct gatgccctcc
7621 tgactctact agctaatgct gttccatcat gcagggaggt gtgctgagct cttgaaagag
7681 gtgagtccac tacccttggt ctacactgca gttcggctcc caagaagccc ctgctggtac
7741 tactaaatcc tgatcctgga gaggagggtt catccatccc ttctctgacc aagacaacca
7801 acagccccag ctggcagctt cagatccatc tgttttgtag tctttggaaa gagcaatctg
7861 ctatgtgacc caagttatcg tgctgggctc ttgggtgtgg gacagaacta ggttagcaga
7921 gagaggtccc ttgtttgtat tgttctgtgc agcaagactg tgcaggttct gggccagctc
7981 tgacccttca tgtcctgacg gtgggatggg gtgttcagct ctgttagatc tcttggggtt
8041 tcctattctg gcaccatgct aactataacc tattcaacct caccgtcaca cccatgcatc
8101 agaagttggc actataaccc attttgcaga gagagcaagg ctcagagagc cagtgctttg
8161 ccaagctagg cagctgaagt gccaggcacc tggcttgtga cacttgacca gtgcttcagg
8221 gtccctggag gccatgcaca gccttgagct ctgctgttct gcccgcaggg actggtctga
8281 gtagctcctg cccaggcctg tggctgcagc cccatctacc tggcctctcc tgctcctgcc
8341 cgaagaacct ctgtatctgc tccaaataaa ttctgctgcc aaatgctgcc cggcgttttt
8401 cctgggggca ggaagggggc gtatgggatg tgtctgtggc ccaagtggaa ggaacagccc
8461 tgcattttct gagaatgatt gtgaatgtgc ctcacacacg gggcagccag tcctagtctc
8521 ccatgtggaa aggtcctact ccaccctgcc ctggcccact catggggcaa tggactccag
8581 tgtctcccct tctcactctg tgacagtgtc cctcctgctc ataagtgctg gtggcacccc
8641 aggatgctac aagcaaaaat gagagcagtc tggagcttgg tgggcagatg gcaaaggttt
8701 tgcagtggtt gctgtgtgaa tcttggagga taagtgtggc agcatacagt tagcaagatc
8761 ctgaaagatt tgtttatttg atcaaaacac aggaggcttt tttttttttt tttttttgca
8821 cagagacttc taagagtaca gatccttact gctggtcata cagcggccgc acaaattctg
8881 gtgccagaag tccatagctt gcttcattgg ccttcaggga tcacttccaa atcacaaatt
8941 ctagcatgag attatcagca tcaagacagc tcagttctga acagacccaa cattcttttg
9001 aggtttgcag ggagga
//