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Sequence 357 from Patent EP2225397

GenBank: HI574220.1

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LOCUS       HI574220                5243 bp    DNA     linear   PAT 28-OCT-2010
DEFINITION  Sequence 357 from Patent EP2225397.
ACCESSION   HI574220
VERSION     HI574220.1
KEYWORDS    .
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1
  AUTHORS   Sekaly,R., Haddad,E., Walker,B. and Eichbaum,Q.
  TITLE     Pd-1 modulation and uses thereof
  JOURNAL   Patent: EP 2225397-A1 357 08-SEP-2010;
            UNIV MONTREAL [CA]
FEATURES             Location/Qualifiers
     source          1..5243
                     /organism="Homo sapiens"
                     /mol_type="unassigned DNA"
                     /db_xref="taxon:9606"
     CDS             2783..4597
                     /note="unnamed protein product"
                     /codon_start=1
                     /protein_id="CBX47599.1"
                     /translation="MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVP
                     VSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSV
                     NNLEATSQPTFPSSVTNSTHSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRS
                     SYHCAMNNENARLLTFQTWPLTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPK
                     DNAMSEHLRHFPKCPFIENQLQDTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQL
                     ASAGFYYVGNSDDVKCFCCDGGLRCWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQV
                     QASYPHLLEQLLSTSDSPGDENAESSIIHFEPGEDHSEDAIMMNTPVINAAVEMGFSR
                     SLVKQTVQRKILATGENYRLVNDLVLDLLNAEDEIREEERERATEEKESNDLLLIRKN
                     RMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTILVKGNIAAT
                     VFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVS
                     IVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRTFLS"
ORIGIN      
        1 agcgtgagac tcgcgccctc cggcacggaa aaggccaggc gacaggtgtc gcttgaaaag
       61 actgggcttg tccttgctgg tgcatgcgtc gtcggcctct gggcagcagg tttacaaagg
      121 aggaaaacga cttcttctag attttttttt cagtttcttc tataaatcaa aacatctcaa
      181 aatggagacc taaaatcctt aaagggactt agtctaatct cgggaggtag ttttgtgcat
      241 gggtaaacaa attaagtatt aactggtgtt ttactatcca aagaatgcta attttataaa
      301 catgatcgag ttatataagg tataccataa tgagtttgat tttgaatttg atttgtggaa
      361 ataaaggaaa agtgattcta gctggggcat attgttaaag catttttttc agagttggcc
      421 aggcagtctc ctactggcac attctcccat tatgtagaat agaaatagta cctgtgtttg
      481 ggaaagattt taaaatgagt gacagttatt tggaacaaag agctaataat caatccactg
      541 caaattaaag aaacatgcag atgaaagttt tgacacatta aaatacttct acagtgacaa
      601 agaaaaatca agaacaaagc tttttgatat gtgcaacaaa tttagaggaa gtaaaaagat
      661 aaatgtgatg attggtcaag aaattatcca gttatttaca aggccactga tattttaaac
      721 gtccaaaagt ttgtttaaat gggctgttac cgctgagaat gatgaggatg agaatgatgg
      781 ttgaaggtta cattttagga aatgaagaaa cttagaaaat taatataaag acagtgatga
      841 atacaaagaa gatttttata acaatgtgta aaatttttgg ccagggaaag gaatattgaa
      901 gttagataca attacttacc tttgagggaa ataattgttg gtaatgagat gtgatgtttc
      961 tcctgccacc tggaaacaaa gcattgaagt ctgcagttga aaagcccaac gtctgtgaga
     1021 tccaggaaac catgcttgca aaccactggt aaaaaaaaaa aaaaaaaaaa aaaaaagcca
     1081 cagtgacttg cttattggtc attgctagta ttatcgactc agaacctctt tactaatggc
     1141 tagtaaatca taattgagaa attctgaatt ttgacaaggt ctctgctgtt gaaatggtaa
     1201 atttattatt ttttttgtca tgataaattc tggttcaagg tatgctatcc atgaaataat
     1261 ttctgaccaa aactaaattg atgcaatttg attatccatc ttagcctaca gatggcatct
     1321 ggtaactttt gactgtttta aaaaataaat ccactatcag agtagatttg atgttggctt
     1381 cagaaacatt tagaaaaaca aaagttcaaa aatgttttca ggaggtgata agttgaataa
     1441 ctctacaatg ttagttcttt gagggggaca aaaaatttaa aatctttgaa aggtcttatt
     1501 ttacagccat atctaaatta tcttaagaaa atttttaaca aagggaatga aatatatatc
     1561 atgattctgt ttttccaaaa gtaacctgaa tatagcaatg aagttcagtt ttgttattgg
     1621 tagtttgggc agagtctctt tttgcagcac ctgttgtcta ccataattac agaggacatt
     1681 tccatgttct agccaagtat actattagaa taaaaaaact taacattgag ttgcttcaac
     1741 agcatgaaac tgagtccaaa agaccaaatg aacaaacaca ttaatctctg attatttatt
     1801 ttaaatagaa tatttaattg tgtaagatct aatagtatca ttatacttaa gcaatcatat
     1861 tcctgatgat ctatgggaaa taactattat ttaattaata ttgaaaccag gttttaagat
     1921 gtgttagcca gtcctgttac tagtaaatct ctttatttgg agagaaattt tagattgttt
     1981 tgttctcctt attagaagga ttgtagaaag aaaaaaatga ctaattggag aaaaattggg
     2041 gatatatcat atttcactga attcaaaatg tcttcagttg taaatcttac cattatttta
     2101 cgtacctcta agaaataaaa gtgcttctaa ttaaaatatg atgtcattaa ttatgaaata
     2161 cttcttgata acagaagttt taaaatagcc atcttagaat cagtgaaata tggtaatgta
     2221 ttattttcct cctttgagtt aggtcttgtg cttttttttc ctggccacta aatttcacaa
     2281 tttccaaaaa gcaaaataaa catattctga atatttttgc tgtgaaacac ttgacagcag
     2341 agctttccac catgaaaaga agcttcatga gtcacacatt acatctttgg gttgattgaa
     2401 tgccactgaa acattctagt agcctggaga agttgaccta cctgtggaga tgcctgccat
     2461 taaatggcat cctgatggct taatacacat cactcttctg tgaagggttt taattttcaa
     2521 cacagcttac tctgtagcat catgtttaca ttgtatgtat aaagattata caaaggtgca
     2581 attgtgtatt tcttccttaa aatgtatcag tataggattt agaatctcca tgttgaaact
     2641 ctaaatgcat agaaataaaa ataataaaaa atttttcatt ttggcttttc agcctagtat
     2701 taaaactgat aaaagcaaag ccatgcacaa aactacctcc ctagagaaag gctagtccct
     2761 tttcttcccc attcatttca ttatgaacat agtagaaaac agcatattct tatcaaattt
     2821 gatgaaaagc gccaacacgt ttgaactgaa atacgacttg tcatgtgaac tgtaccgaat
     2881 gtctacgtat tccacttttc ctgctggggt tcctgtctca gaaaggagtc ttgctcgtgc
     2941 tggtttctat tacactggtg tgaatgacaa ggtcaaatgc ttctgttgtg gcctgatgct
     3001 ggataactgg aaaagaggag acagtcctac tgaaaagcat aaaaagttgt atcctagctg
     3061 cagattcgtt cagagtctaa attccgttaa caacttggaa gctacctctc agcctacttt
     3121 tccttcttca gtaacaaatt ccacacactc attacttccg ggtacagaaa acagtggata
     3181 tttccgtggc tcttattcaa actctccatc aaatcctgta aactccagag caaatcaaga
     3241 tttttctgcc ttgatgagaa gttcctacca ctgtgcaatg aataacgaaa atgccagatt
     3301 acttactttt cagacatggc cattgacttt tctgtcgcca acagatctgg caaaagcagg
     3361 cttttactac ataggacctg gagacagagt ggcttgcttt gcctgtggtg gaaaattgag
     3421 caattgggaa ccgaaggata atgctatgtc agaacacctg agacattttc ccaaatgccc
     3481 atttatagaa aatcagcttc aagacacttc aagatacaca gtttctaatc tgagcatgca
     3541 gacacatgca gcccgcttta aaacattctt taactggccc tctagtgttc tagttaatcc
     3601 tgagcagctt gcaagtgcgg gtttttatta tgtgggtaac agtgatgatg tcaaatgctt
     3661 ttgctgtgat ggtggactca ggtgttggga atctggagat gatccatggg ttcaacatgc
     3721 caagtggttt ccaaggtgtg agtacttgat aagaattaaa ggacaggagt tcatccgtca
     3781 agttcaagcc agttaccctc atctacttga acagctgcta tccacatcag acagcccagg
     3841 agatgaaaat gcagagtcat caattatcca ttttgaacct ggagaagacc attcagaaga
     3901 tgcaatcatg atgaatactc ctgtgattaa tgctgccgtg gaaatgggct ttagtagaag
     3961 cctggtaaaa cagacagttc agagaaaaat cctagcaact ggagagaatt atagactagt
     4021 caatgatctt gtgttagact tactcaatgc agaagatgaa ataagggaag aggagagaga
     4081 aagagcaact gaggaaaaag aatcaaatga tttattatta atccggaaga atagaatggc
     4141 actttttcaa catttgactt gtgtaattcc aatcctggat agtctactaa ctgccggaat
     4201 tattaatgaa caagaacatg atgttattaa acagaagaca cagacgtctt tacaagcaag
     4261 agaactgatt gatacgattt tagtaaaagg aaatattgca gccactgtat tcagaaactc
     4321 tctgcaagaa gctgaagctg tgttatatga gcatttattt gtgcaacagg acataaaata
     4381 tattcccaca gaagatgttt cagatctacc agtggaagaa caattgcgga gactacaaga
     4441 agaaagaaca tgtaaagtgt gtatggacaa agaagtgtcc atagtgttta ttccttgtgg
     4501 tcatctagta gtatgcaaag attgtgctcc ttctttaaga aagtgtccta tttgtaggag
     4561 tacaatcaag ggtacagttc gtacatttct ttcatgaaga agaaccaaaa catcgtctaa
     4621 actttagaat taatttatta aatgtattat aactttaact tttatcctaa tttggtttcc
     4681 ttaaaatttt tatttattta caactcaaaa aacattgttt tgtgtaacat atttatatat
     4741 gtatctaaac catatgaaca tatatttttt agaaactaag agaatgatag gcttttgttc
     4801 ttatgaacga aaaagaggta gcactacaaa cacaatattc aatcaaaatt tcagcattat
     4861 tgaaattgta agtgaagtaa aacttaagat atttgagtta acctttaaga attttaaata
     4921 ttttggcatt gtactaatac cgggaacatg aagccaggtg tggtggtatg tgcctgtagt
     4981 cccaggctga ggcaagagaa ttacttgagc ccaggagttt gaatccatcc tgggcagcat
     5041 actgagaccc tgcctttaaa aacaaacaga acaaaaacaa aacaccaggg acacatttct
     5101 ctgtcttttt tgatcagtgt cctatacatc gaaggtgtgc atatatgttg aatgacattt
     5161 tagggacatg gtgtttttat aaagaattct gtgagaaaaa atttaataaa gcaacaaaaa
     5221 ttactcttaa aaaaaaaaaa aaa
//
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