LOCUS BC018142 2621 bp mRNA linear PRI 03-OCT-2003
DEFINITION Homo sapiens caspase recruitment domain family, member 14, mRNA
(cDNA clone MGC:9539 IMAGE:3847282), complete cds.
ACCESSION BC018142
VERSION BC018142.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2621)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2621)
AUTHORS Strausberg,R.
TITLE Direct Submission
JOURNAL Submitted (03-DEC-2001) National Institutes of Health, Mammalian
Gene Collection (MGC), Cancer Genomics Office, National Cancer
Institute, 31 Center Drive, Room 11A03, Bethesda, MD 20892-2590,
USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 20 Row: i Column: 3
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 16507953.
FEATURES Location/Qualifiers
source 1..2621
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:9539 IMAGE:3847282"
/tissue_type="Colon, adenocarcinoma"
/clone_lib="NIH_MGC_65"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..2621
/gene="CARD14"
/gene_synonym="BIMP2"
/gene_synonym="CARMA2"
/db_xref="GeneID:79092"
/db_xref="MIM:607211"
CDS 178..2400
/gene="CARD14"
/gene_synonym="BIMP2"
/gene_synonym="CARMA2"
/codon_start=1
/product="CARD14 protein"
/protein_id="AAH18142.1"
/db_xref="GeneID:79092"
/db_xref="MIM:607211"
/translation="MGELCRRDSALTALDEETLWEMMESHRHRIVRCICPSRLTPYLR
QAKVLCQLDEEEVLHSPRLTNSAMRAGHLLDLLKTRGKNGAIAFLESLKFHNPDVYTL
VTGLQPDVDFSNFSGLMETSKLTECLAGAIGSLQEELNQEKGQKEVLLRRCQQLQEHL
GLAETRAEGLHQLEADHSRMKREVSAHFHEVLRLKDEMLSLSLHYSNALQEKELAASR
CRSLQEELYLLKQELQRANMVSSCELELQEQSLRTASDQESGDEELNRLKEENEKLRS
LTFSLAEKDILEQSLDEARGSRQELVERIHSLRERAVAAERQREQYWEEKEQTLLQFQ
KSKMACQLYREKVNALQAQVCELQKERDQAYSARDSAQREISQSLVEKDSLRRQVFEL
TDQVCELRTQLRQLQAEPPGVLKQEARTREPCPREKQRLVRMHAICPRDDSDCSLVSS
TESQLLSDLSATSSRELVDSFRSSSPAPPSQQSLYKRVAEDFGEEPWSFSSCLEIPEG
DPGALPGAKAGDPHLDYELLDTADLPQLESSLQPVSPGRLDVSESGVLMRRRPARRIL
SQVTMLAFQGDALLEQISVIGGNLTGIFIHRVTPGSAADQMALRPGTQIVMVDYEASE
PLFKAVLEDTTLEEAVGLLRRVDGFCCLSVKVNTDGYKRLLQDLEAKVATSGDSFYIR
VNLAMEGRAKGELQVHCNEVLHVTDTMFQGCGCWHAHRVNSYTMKDTAAHGTIPNYSR
"
misc_feature 1150..1404
/gene="CARD14"
/gene_synonym="BIMP2"
/gene_synonym="CARMA2"
/note="Myosin_tail; Region: Myosin tail. The myosin
molecule is a multi-subunit complex made up of two heavy
chains and four light chains it is a fundamental
contractile protein found in all eukaryote cell types.
This family consists of the coiled-coil myosin heavy chain
tail region. The coiled-coil is composed of the tail from
two molecules of myosin. These can then assemble into the
macromolecular thick filament. The coiled-coil region
provides the structural backbone the thick filament"
/db_xref="CDD:pfam01576"
misc_feature 1924..2142
/gene="CARD14"
/gene_synonym="BIMP2"
/gene_synonym="CARMA2"
/note="PDZ; Region: Domain present in PSD-95, Dlg, and
ZO-1/2. Also called DHR (Dlg homologous region) or GLGF
(relatively well conserved tetrapeptide in these domains).
Some PDZs have been shown to bind C-terminal polypeptides"
/db_xref="CDD:smart00228"
ORIGIN
1 tgacttcagg ctcttccttc tgcccagctc cgtcccaccc agcagcccgc agagaaagga
61 ggcagctggc accacactgg gctttggaga cactgcgggg actgtggacc ccaccctgct
121 gcacggagct cctgcaaaag caaacctgag aaccttgggt cctcccagcg cccagccatg
181 ggggaactgt gccgcaggga ctccgcactc acggcactgg acgaggagac actgtgggag
241 atgatggaga gccaccgcca caggatcgta cgctgcatct gccccagccg cctcaccccc
301 tacctgcgcc aggccaaggt gctgtgccag ctggacgagg aggaggtgct gcacagcccc
361 cggctcacca acagcgccat gcgggccggg cacttgctgg atttgctgaa gactcgaggg
421 aagaacgggg ccatcgcctt cctggagagc ctgaagttcc acaaccctga cgtctacacc
481 ctggtcaccg ggctgcagcc tgatgttgac ttcagtaact ttagcggtct catggagaca
541 tccaagctga ccgagtgcct ggctggggcc atcggcagcc tgcaggagga gctgaaccag
601 gaaaaggggc agaaggaggt gctgctgcgg cggtgccagc agctgcagga gcacctgggc
661 ctggccgaga cccgtgccga gggcctgcac cagctggagg ctgaccacag ccgcatgaag
721 cgtgaggtta gcgcacactt ccatgaggtg ctgaggctga aggacgagat gctcagcctc
781 tcgctgcact atagcaatgc gctgcaggaa aaggagctgg ccgcctcacg ctgccgcagc
841 ctgcaggagg agctgtatct actgaagcag gagctgcagc gagccaacat ggtttcctcc
901 tgtgagctgg aattgcaaga gcagtccctg aggacagcca gcgaccagga gtccggggat
961 gaggagctga accgcctgaa ggaggagaat gagaaactgc gctcgctgac tttcagcctg
1021 gcggagaagg acattctgga gcagagcctg gacgaggcgc gggggagccg acaggagctg
1081 gtggagcgca tccactcgct gcgggagcgg gccgtggctg ccgagaggca gcgagagcag
1141 tactgggaag agaaggaaca gaccctgctg cagttccaga agagtaagat ggcctgccaa
1201 ctctacaggg agaaggtgaa tgcgctgcag gcccaggtgt gcgagctgca gaaggagcga
1261 gaccaggcgt actccgcgag ggacagtgct cagagggaga tttcccagag cctggtggag
1321 aaggactccc tccgcaggca ggtgttcgag ctgacggacc aggtctgcga gctgcgcaca
1381 cagcttcgcc agctgcaggc agagcctccg ggtgtgctca agcaggaagc caggaccagg
1441 gagccctgtc cacgggagaa gcagcggctg gtgcggatgc atgccatctg ccccagagac
1501 gacagcgact gcagcctcgt cagctccaca gagtctcagc tcttgtcgga cctgagtgcc
1561 acgtccagcc gcgagctggt ggacagcttc cgctccagca gccccgcgcc ccccagccag
1621 cagtccctgt acaagcgggt ggccgaggac ttcggggaag aaccctggtc tttcagcagc
1681 tgcctggaga tcccggaggg agacccggga gccctgccgg gagctaaggc aggcgaccca
1741 cacctggatt atgagctcct agacacggca gaccttccgc agctggaaag cagcctgcag
1801 ccagtctccc ctggaaggct tgatgtctcg gagagcggcg tcctcatgcg gcggaggcca
1861 gcccgcagga tcctgagcca ggtcaccatg ctggcgttcc agggggatgc attgctggag
1921 cagatcagcg tcatcggcgg gaacctcacg ggcatcttca tccaccgggt caccccgggc
1981 tcggcggcgg accagatggc cttgcgcccg ggcacccaga ttgtgatggt tgattacgaa
2041 gcctcagagc ccttgttcaa ggcagtcctg gaggacacga ccctggagga ggccgtgggg
2101 cttctcagga gggtggacgg cttctgctgc ctgtctgtga aggtcaacac ggacggttat
2161 aagaggctac tccaggacct ggaggccaaa gtggcgacct cgggggactc attctacatc
2221 cgggtcaacc tggccatgga gggcagggcc aaaggggagc tgcaggtgca ttgcaacgag
2281 gtcctgcacg tcaccgacac catgttccag ggctgcggct gctggcatgc ccaccgcgtg
2341 aactcttaca ccatgaagga tactgccgcg cacggcacca tccccaacta ctccaggtga
2401 gcagctgcct cgagctcggt gcgtccccag agaggcccac agggaaatgg cacccagcct
2461 gcctcggctt cctcctcctg cccagcaata gagggtgggc gtggtgagac ccccctaagg
2521 agggaagcct gccaagatca ctgctgaaga tgttgtttct ttgtgatgga tgctttatat
2581 attgcaaatg aaatgttcat tctagaaaaa aaaaaaaaaa a
//