MeSH

Precursor of epinephrine that is secreted by the ADRENAL MEDULLA and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers, and of the diffuse projection system in the brain that arises from the LOCUS CERULEUS. It is also found in plants and is used pharmacologically as a sympathomimetic.

Year introduced: 1993 (1963)

Drugs that selectively bind to and activate alpha adrenergic receptors.

Year introduced: 1995

Drugs used to cause constriction of the blood vessels.

Year introduced: 1967(1965)

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Organic compounds composed exclusively of carbon and hydrogen forming a closed ring that may be either alicyclic or aromatic.

Year introduced: 1998

Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant and Hackh's Chemical Dictionary, 5th ed)

A group of compounds derived from ammonia by substituting organic radicals for the hydrogens. (From Grant and Hackh's Chemical Dictionary, 5th ed)

Compounds possessing both a hydroxyl (-OH) and an amino group (-NH2).

Organic compounds derived from BENZENE.

Year introduced: 1968

A group of naturally occurring amines derived by enzymatic decarboxylation of the natural amino acids. Many have powerful physiological effects (e.g., histamine, serotonin, epinephrine, tyramine). Those derived from aromatic amino acids, and also their synthetic analogs (e.g., amphetamine), are of use in pharmacology.

Year introduced: 1973(1971)

A general class of ortho-dihydroxyphenylalkylamines derived from TYROSINE.

A group of 1,2-benzenediols that contain the general formula R-C6H5O2.

Year introduced: 1975

AMINO ALCOHOLS containing the ETHANOLAMINE; (-NH2CH2CHOH) group and its derivatives.

Year introduced: 1973

Organic compounds that primarily contain carbon and hydrogen atoms with the carbon atoms forming a linear or circular structure.

Organic compounds containing carbon and hydrogen in the form of an unsaturated, usually hexagonal ring structure. The compounds can be single ring, or double, triple, or multiple fused rings.

Year introduced: 1998

A broad class of substances containing carbon and its derivatives. Many of these chemicals will frequently contain hydrogen with or without oxygen, nitrogen, sulfur, phosphorus, and other elements. They exist in either carbon chain or carbon ring form.

Year introduced: 1998

Benzene derivatives that include one or more hydroxyl groups attached to the ring structure.

Biogenic amines having only one amine moiety. Included in this group are all natural monoamines formed by the enzymatic decarboxylation of natural amino acids.

Year introduced: 1989

Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.

Year introduced: 2004

Drugs that act principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. (From Smith and Reynard, Textbook of Pharmacology, 1991, p75)

Year introduced: 1998