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Serotonin Plasma Membrane Transport Proteins

Sodium chloride-dependent neurotransmitter symporters located primarily on the PLASMA MEMBRANE of serotonergic neurons. They are different than SEROTONIN RECEPTORS, which signal cellular responses to SEROTONIN. They remove SEROTONIN from the EXTRACELLULAR SPACE by high affinity reuptake into PRESYNAPTIC TERMINALS. Regulates signal amplitude and duration at serotonergic synapses and is the site of action of the SELECTIVE SEROTONIN REUPTAKE INHIBITORS.

Year introduced: 2006(1992)

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Tree Number(s): D12.776.157.530.450.625.311, D12.776.157.530.562.374.875, D12.776.157.530.937.624, D12.776.543.585.450.625.374, D12.776.543.585.562.374.875, D12.776.543.585.937.747

MeSH Unique ID: D050486

Entry Terms:

  • Neurotransmitter Transporters, Serotonin-Specific
  • Neurotransmitter Transporters, Serotonin Specific
  • Serotonin-Specific Neurotransmitter Transporters
  • Neurotransmitter Transport Proteins, Serotonin-Specific
  • Neurotransmitter Transport Proteins, Serotonin Specific
  • Serotonin Plasma Membrane Transporter Proteins
  • SERT Proteins
  • 5-Hydroxytryptamine Plasma Membrane Transport Protein
  • 5 Hydroxytryptamine Plasma Membrane Transport Protein
  • Serotonin Transporter
  • Serotonectin
  • Serotonin Transporter, Platelets
  • Platelets Serotonin Transporter
  • Platelet Serotonin Transporter
  • Serotonin Transporter, Platelet
  • Solute Carrier Family 6, Member 4 Protein
  • SLC6A4 Protein
  • Sodium-Dependent Serotonin Transporter
  • Serotonin Transporter, Sodium-Dependent
  • Sodium Dependent Serotonin Transporter
  • Transporter, Sodium-Dependent Serotonin
  • 5HT Transporter

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