CD40 Antigens
Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Year introduced: 2018 (1988)
PubMed search builder options
Subheadings:
Tree Number(s): D12.776.465.750, D12.776.543.750.705.852.760.097, D23.050.301.264.051.140, D23.101.100.150.140
MeSH Unique ID: D019013
Entry Terms:
- Tumor Necrosis Factor Receptor Superfamily, Member 5
- TNFRSF5 Receptor
- Receptor, TNFRSF5
- CD40 Antigen
- Antigen, CD40
- Antigens, CD40
- CDw40 Antigen
- Antigen, CDw40
Previous Indexing:
See Also: