Myelinolysis, Central Pontine
A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
Year introduced: 1994
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Subheadings:
Tree Number(s): C10.228.140.163.560, C10.314.500, C18.452.132.560
MeSH Unique ID: D017590
Entry Terms:
- Myelinoclasis, Central Pontine
- Central Pontine Myelinoclasis
- Central Pontine Myelinolysis
- Pontine Myelinolysis, Central
- Extrapontine Myelinolysis
- Extrapontine Myelinolyses
- Myelinolyses, Extrapontine
- Myelinolysis, Extrapontine
- Extrapontine Myelinoclasis
- Extrapontine Myelinoclases
- Myelinoclases, Extrapontine
- Myelinoclasis, Extrapontine
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