Steroid 11-beta-Hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
Year introduced: 2003 (1978)
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Tree Number(s): D08.244.453.484.750, D08.244.453.915.750, D08.811.682.690.708.170.425.750, D08.811.682.690.708.170.915.750, D12.776.422.220.453.484.750, D12.776.422.220.453.915.750
MeSH Unique ID: D013252
Registry Number: EC 1.14.15.4
Entry Terms:
- Steroid 11 beta Hydroxylase
- Cytochrome P-450(11 beta)
- Steroid 11 Hydroxylase
- Steroid-11-Hydroxylase
- Steroid 11-Hydroxylase
- CYP11B1
- Steroid 11-beta-Monooxygenase
- Steroid 11 beta Monooxygenase
- CYP 11B1
- Cytochrome P450 11B1
- 11 beta-Hydroxylase
- 11 beta Hydroxylase
- Cytochrome P-450 CYP11B1
- Cytochrome P 450 CYP11B1
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