Complement C7

A 93-kDa serum glycoprotein encoded by C7 gene. It is a polypeptide chain with 28 disulfide bridges. In the formation of MEMBRANE ATTACK COMPLEX; C7 is the next component to bind the C5b-6 complex forming a trimolecular complex C5b-7 which is lipophilic, resembles an integral membrane protein, and serves as an anchor for the late complement components, C8 and C9.

Year introduced: 2006 (1975)

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Tree Number(s): D12.776.124.486.274.650

MeSH Unique ID: D003184

Entry Terms:

• C7, Complement
• C7 Complement
• Complement, C7
• Complement 7
• Complement Component 7
• Component 7, Complement

Previous Indexing:

• Chemotaxis (1966-1974)
• Complement (1968-1974)
• Neutrophils (1966-1974)

Pharmacologic Action:

• Immunologic Factors

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Proteins
Blood Proteins
Immunoproteins
Complement System Proteins
Complement C7