Cathepsin B
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.
Year introduced: 1987
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Subheadings:
Tree Number(s): D08.811.277.656.224.125, D08.811.277.656.262.500.133, D08.811.277.656.300.200.133
MeSH Unique ID: D002401
Registry Number: EC 3.4.22.1
Entry Terms:
- Cathepsin B1
- Cathepsin B-Like Proteinase
- Cathepsin B Like Proteinase
- Proteinase, Cathepsin B-Like
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