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Tumor Necrosis Factor alpha-Induced Protein 3

A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.

Year introduced: 2017

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Tree Number(s): D08.811.037.750.500, D08.811.277.656.300.887.750, D08.811.464.938.750.813, D12.644.360.950, D12.776.476.938

MeSH Unique ID: D000072598

Registry Number: EC 3.4.19.12

Entry Terms:

  • Tumor Necrosis Factor alpha Induced Protein 3
  • TNFAIP3 Protein
  • Zinc Finger Protein A20

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